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pro vyhledávání: '"Socheata, Lim"'
Publikováno v:
Biomolecular NMR Assignments. 16:317-323
Publikováno v:
Biomolecular NMR assignments. 16(2)
The ring-shaped E. coli β-clamp protein is an 81 kDa head-to-tail homodimer, which serves as a processivity factor anchoring the replicative polymerase to DNA, thereby increasing replication processivity and speed. In addition, it facilitates numero
Autor:
Melissa Lizette Liriano, Alessandro A. Rizzo, Kevin Jeanne Dit Fouque, Bilyana N. Koleva, G. Andrés Cisneros, Hatice Gökcan, Dmitry M. Korzhnev, Francisco Fernandez-Lima, Socheata Lim, Penny J. Beuning, Angelina Choy
Publikováno v:
Biophys J
The ring-shaped sliding clamp proteins have crucial roles in the regulation of DNA replication, recombination, and repair in all organisms. We previously showed that the Escherichia coli β-clamp is dynamic in solution, transiently visiting conformat
Autor:
Socheata Lim, Dmitry M. Korzhnev, Zuleyha Ozen, Alessandro A. Rizzo, M. Kyle Hadden, Radha Charan Dash
Publikováno v:
Journal of chemical information and modeling. 58(11)
Translesion synthesis (TLS) is a mechanism of replication past damaged DNA through which multiple forms of human cancer survive and acquire resistance to first-line genotoxic chemotherapies. As such, TLS is emerging as a promising target for the deve
Autor:
Judith Helena Prieto, Socheata Lim
Publikováno v:
Biophysical Journal. 108(2):55a-56a
Plasmodium falciparum is the cause of human malaria and is one of two malaria parasites known to have drug resistance. Since there are no preventative vaccinations against malaria, the control of this disease is heavily dependent upon the use of anti