Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues.

Autor: Sobhi HF; Center for Organic Synthesis, Department of Natural Sciences, Coppin State University, Baltimore, Maryland, USA. Electronic address: hsobhi@coppin.edu., Mercer KE; Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA; Arkansas Children's Nutrition Center, Little Rock, Arkansas, USA., Lan RS; Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA; Arkansas Children's Nutrition Center, Little Rock, Arkansas, USA., Yeruva L; Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA; Arkansas Children's Nutrition Center, Little Rock, Arkansas, USA; USDA-ARS Southeast Area, Microbiome and Metabolism Research Unit, Arkansas Children's Nutrition Center, Little Rock, Arkansas, USA., Ten Have GAM; Center for Translational Research in Aging and Longevity, Department of Health and Kinesiology, Texas A & M University, College Station, Texas, USA., Deutz NEP; Center for Translational Research in Aging and Longevity, Department of Health and Kinesiology, Texas A & M University, College Station, Texas, USA., Piccolo BD; Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA; Arkansas Children's Nutrition Center, Little Rock, Arkansas, USA., Debédat J; Department of Surgery, University of California Davis School of Medicine, Sacramento, California, USA; Center for Alimentary and Metabolic Science, University of California Davis School of Medicine, Sacramento, California, USA., Pack LM; Arkansas Children's Nutrition Center, Little Rock, Arkansas, USA., Adams SH; Department of Surgery, University of California Davis School of Medicine, Sacramento, California, USA; Center for Alimentary and Metabolic Science, University of California Davis School of Medicine, Sacramento, California, USA. Electronic address: shadams@ucdavis.edu.

Publikováno v: Journal of lipid research [J Lipid Res] 2024 Oct; Vol. 65 (10), pp. 100632. Date of Electronic Publication: 2024 Aug 27.

T3P-Promoted Synthesis of a Series of 2-Aryl-3-phenyl-2,3-dihydro-4 H -pyrido[3,2- e ][1,3]thiazin-4-ones and Their Activity against the Kinetoplastid Parasite Trypanosoma brucei .

Autor: Silverberg LJ; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Mal TK; Department of Chemistry, Pennsylvania State University, 104 Chemistry Building, Room 08, University Park, State College, PA 16802, USA., Pacheco CN; Department of Chemistry, Pennsylvania State University, 104 Chemistry Building, Room 08, University Park, State College, PA 16802, USA.; Chemistry and Environmental Science, New Jersey Institute of Technology, Tiernan Hall, Room B006, University Heights, Newark, NJ 07102, USA., Povelones ML; Mendel Science Center, Department of Biology, Villanova University, 800 Lancaster Avenue, Villanova, PA 19085, USA., Malfara MF; Mendel Science Center, Department of Biology, Villanova University, 800 Lancaster Avenue, Villanova, PA 19085, USA., Lagalante AF; Mendel Science Center, Department of Chemistry, Villanova University, 800 Lancaster Avenue, Villanova, PA 19085, USA., Olsen MA; Mendel Science Center, Department of Chemistry, Villanova University, 800 Lancaster Avenue, Villanova, PA 19085, USA., Yennawar HP; Department of Biochemistry and Molecular Biology, Pennsylvania State University, 8 Althouse Laboratory, University Park, State College, PA 16802, USA., Sobhi HF; Center for Organic Synthesis Coppin State University, Room-229, 2500 West North Avenue, Baltimore, MD 21216, USA., Baney KR; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Bozeman RL; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Eroh CS; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Fleming MJ; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Garcia TL; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Gregory CL; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Hahn JE; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Hatter AM; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Johns LL; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Klinger TL; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Li JJ; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Menig AJ; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Muench GC; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Ramirez ME; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Reilly J; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Sacco N; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Sheidy AM; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Stoner MM; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Thompson EN; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA., Yazdani SF; Schuylkill Campus, Pennsylvania State University, 200 University Drive, Schuylkill Haven, PA 17972, USA.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2021 Oct 09; Vol. 26 (20). Date of Electronic Publication: 2021 Oct 09.

Identification and regulation of the xenometabolite derivatives cis - and trans -3,4-methylene-heptanoylcarnitine in plasma and skeletal muscle of exercising humans.

Autor: Sobhi HF; Department of Natural Sciences, Center for Organic Synthesis, Coppin State University, Baltimore, Maryland., Zhao X; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Dalian, China., Plomgaard P; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark.; The Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Department of Infectious Diseases and CMRC, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hoene M; Institute for Clinical Chemistry and Pathobiochemistry, University Hospital, Tuebingen, Germany., Hansen JS; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen, Denmark.; The Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Department of Infectious Diseases and CMRC, Rigshospitalet, Copenhagen, Denmark., Karus B; Department for Sports Medicine, University Hospital, Tuebingen, Germany., Niess AM; Department for Sports Medicine, University Hospital, Tuebingen, Germany., Häring HU; Institute for Diabetes Research and Metabolic Diseases, Helmholtz Zentrum Muenchen, University of Tuebingen, Tuebingen, Germany.; German Center for Diabetes Research, Oberschleissheim, Germany., Lehmann R; Institute for Clinical Chemistry and Pathobiochemistry, University Hospital, Tuebingen, Germany.; Institute for Diabetes Research and Metabolic Diseases, Helmholtz Zentrum Muenchen, University of Tuebingen, Tuebingen, Germany.; German Center for Diabetes Research, Oberschleissheim, Germany., Adams SH; Arkansas Children's Nutrition Center, Little Rock, Arkansas.; Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas., Xu G; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Dalian, China., Weigert C; Institute for Clinical Chemistry and Pathobiochemistry, University Hospital, Tuebingen, Germany.; Institute for Diabetes Research and Metabolic Diseases, Helmholtz Zentrum Muenchen, University of Tuebingen, Tuebingen, Germany.; German Center for Diabetes Research, Oberschleissheim, Germany.

Publikováno v: American journal of physiology. Endocrinology and metabolism [Am J Physiol Endocrinol Metab] 2020 May 01; Vol. 318 (5), pp. E701-E709. Date of Electronic Publication: 2020 Feb 26.

The mechanism of Intralipid®-mediated cardioprotection complex IV inhibition by the active metabolite, palmitoylcarnitine, generates reactive oxygen species and activates reperfusion injury salvage kinases.

Autor: Lou PH; Postdoctoral Fellow, Cardiovascular Research Centre, University of Alberta, Edmonton, AB, Canada., Lucchinetti E; Research Associate, Department of Anesthesiology & Pain Medicine, University of Alberta, Edmonton, AB, Canada., Zhang L; Research Associate, Department of Anesthesiology & Pain Medicine, University of Alberta, Edmonton, AB, Canada., Affolter A; Research Associate, Department of Clinical Chemistry, University Children's Hospital Zurich, Zurich, Switzerland., Schaub MC; Professor, Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland., Gandhi M; Research Associate, Department of Pharmacology, University of Alberta, Edmonton, AB, Canada., Hersberger M; Head of the Department of Clinical Chemistry, University Children's Hospital Zurich, Zurich, Switzerland., Warren BE; Undergraduate student, Campus Saint-Jean, University of Alberta, Edmonton, AB, Canada., Lemieux H; Assistant Professor, Campus Saint-Jean, University of Alberta, Edmonton, AB, Canada., Sobhi HF; Assistant Professor and Director of Coppin Center for Organic Synthesis, Coppin State University, Baltimore, Maryland, United States of America., Clanachan AS; Professor, Department of Pharmacology, University of Alberta, Edmonton, AB, Canada., Zaugg M; Professor, Department of Anesthesiology & Pain Medicine, University of Alberta, Edmonton, AB, Canada.

Publikováno v: PloS one [PLoS One] 2014 Jan 30; Vol. 9 (1), pp. e87205. Date of Electronic Publication: 2014 Jan 30 (Print Publication: 2014).