Allogeneic B cell immunomodulatory therapy in amyotrophic lateral sclerosis.

Autor: Sîrbulescu RF; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Sean M. Healey and AMG Center for ALS, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Nicholson K; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Sean M. Healey and AMG Center for ALS, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Kawai K; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Hilton OM; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Sobell D; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Jin G; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Verrill DE; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Dwyer LJ; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Xiong Y; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Bachanová P; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Kim SE; Sean M. Healey and AMG Center for ALS, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Gallup S; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Gelevski D; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Daley H; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Hernandez Rodriguez DE; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Negre H; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Sturtevant O; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Nikiforow S; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Ritz J; Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Chen YB; The Connell and O'Reilly Families Cell Manipulation Core Facility, Dana-Farber Cancer Center, Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, USA., Reeves PM; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Sluder AE; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Berry JD; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Sean M. Healey and AMG Center for ALS, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Sadri-Vakili G; Sean M. Healey and AMG Center for ALS, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Cudkowicz M; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Sean M. Healey and AMG Center for ALS, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Poznansky MC; Vaccine and Immunotherapy Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; The Connell and O'Reilly Families Cell Manipulation Core Facility, Dana-Farber Cancer Center, Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, USA.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Jul 15; Vol. 38 (13), pp. e23796.

B cells support the repair of injured tissues by adopting MyD88-dependent regulatory functions and phenotype.

Autor: Sîrbulescu RF; Vaccine and Immunotherapy Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Mamidi A; Vaccine and Immunotherapy Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; School of Chemical and Biochemical Engineering, Nanyang Technological University, Singapore, Singapore., Chan SC; Vaccine and Immunotherapy Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Jin G; Vaccine and Immunotherapy Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Neuroscience Center, Department of Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Boukhali M; Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Sobell D; Vaccine and Immunotherapy Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Ilieş I; Healthcare Systems Engineering Institute, Department of Mechanical and Industrial Engineering, Northeastern University, Boston, Massachusetts, USA., Chung JY; Neuroscience Center, Department of Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Haas W; Center for Cancer Research, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Whalen MJ; Neuroscience Center, Department of Pediatrics, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Sluder AE; Vaccine and Immunotherapy Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Poznansky MC; Vaccine and Immunotherapy Center, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Dec; Vol. 35 (12), pp. e22019.

Harnessing CXCL12 signaling to protect and preserve functional β-cell mass and for cell replacement in type 1 diabetes.

Autor: Alagpulinsa DA; Vaccine and Immunotherapy Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA., Cao JJL; Vaccine and Immunotherapy Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA; Department of Pathology and School of Clinical Medicine, University of Cambridge, Cambridge, CB2 1TN, UK., Sobell D; Vaccine and Immunotherapy Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA., Poznansky MC; Vaccine and Immunotherapy Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA. Electronic address: mark_poznansky@dfci.harvard.edu.

Publikováno v: Pharmacology & therapeutics [Pharmacol Ther] 2019 Jan; Vol. 193, pp. 63-74. Date of Electronic Publication: 2018 Aug 24.

Breg-Mediated Immunoregulation in the Skin.

Autor: Zheremyan, Elina A.¹ (AUTHOR), Ustiugova, Alina S.¹ (AUTHOR), Karamushka, Nina M.^1,2 (AUTHOR), Uvarova, Aksinya N.¹ (AUTHOR), Stasevich, Ekaterina M.¹ (AUTHOR), Bogolyubova, Apollinariya V.³ (AUTHOR), Kuprash, Dmitry V.^1,2 (AUTHOR), Korneev, Kirill V.^1,3 (AUTHOR) kirkorneev@gmail.com

Publikováno v: International Journal of Molecular Sciences. Jan2024, Vol. 25 Issue 1, p583. 15p.

SOCS3 inhibits the mesenchymal stromal cell secretory factor SDF-1-mediated improvement of islet function in non-obese diabetic mice.

Autor: Sui, Mingxing¹ (AUTHOR), Li, Tuo² (AUTHOR), Lu, Hanlan¹ (AUTHOR), Li, Yanhua¹ (AUTHOR), Huang, Juan¹ (AUTHOR), Zhang, Pei¹ (AUTHOR), Wang, Shusen³ (AUTHOR) shusen@vip.163.com, Zeng, Li¹ (AUTHOR) shchyysyz@smmu.edu.cn

Publikováno v: Stem Cell Research & Therapy. 7/3/2023, Vol. 14 Issue 1, p1-13. 13p.