Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Soad M. Abdel Gawad"'
Publikováno v:
Medicinal Chemistry Research. 27:72-79
The utility of 4-isothiocyanato-N-(1-phenyl-1H-pyrazol-5-yl)benzene sulfonamide 2 in the synthesis of some novel thiosemicarbazide, carbamothioate,1,3,4-thiadiazole, azomethine, thiourea, bisthiourea and imidazole derivatives is reported. The structu
Autor:
Hala M. Aly, Zeinab H. Ismail, M. M. Ghorab, Mohamed S. A. El-Gaby, Soad M. Abdel-Gawad, Saleh I. Alqasoumi
Publikováno v:
Arzneimittelforschung. 59:666-671
4-Amino-N-(1-phenyl-1H-pyrazol-5-yl)-benzenesulfonamide (sulfaphenazole) 1 was selected as strategic starting material for the synthesis of some novel acetamide 2, pyrrole 4, pyrrolo[2,3-d]pyrimidine 5, thiocyanate 6, hydrazone 7a,b pyrazole 8, isoth
Publikováno v:
Saudi Pharmaceutical Journal. 18(1):27-33
Estrogens, and particularly glucuronides such as ethinylestradiol (EE), have been shown to cause cholestasis in animal studies, by reducing bile acid uptake by hepatocytes. The aim of the present article is to investigate anticholestatic activity of
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 184:2645-2654
The non-isolated adducts (3a,b) were used as key intermediates to synthesize some novel thiazolidine and thiophene derivatives. Compound (4) exhibited a remarkable antitumor activity against EAC ce...
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 184:58-75
Thieno[2,3-b]pyridines were synthesized from 6-benzofuran-2-yl-4-phenyl-2-sulfanylpyridine-3-carbonitrile and each of chloro acetone, ethyl chloroacetate, ω -bromoacetophenone, and chloroacetonitrile. These compounds were conveniently converted into
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 181:279-297
Thieno [2,3-b] quinoline derivative 5 was synthesized by the cycloalkylation of compound bi 3a with chloro acetonitrile. Interaction of compound 5 with formic acid, formamide, and thioacetamide furnished the corresponding quinolino[3′,2′:4,5]thie
Publikováno v:
Journal of the Chinese Chemical Society. 52:1227-1236
A new series of hydroquinolines 6a-d, 10, 12, 15, 17b, 20 and pyrimidoquinolines 7, 8, 9a, 11, 14 and 16 were synthesized starting from 2-amino-4-(3-bromo-phenyl)-7,7-dimethyl-1-naphthalen-1-yl-5-oxo-1,4,5,6,7,8-hexahydro-quinoline-3-carbonitrile 6b.
Autor:
Soad M. Abdel-Gawad
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 180:2303-2314
Coumarine, thiazole, thiophene and 2,3-dihydro-1,3,4-thiadiazole derivatives were synthesized from 2-[4-(4-methyl-2-phenyl-1,3-thiazol.-5-yl)-1,3-thiazol-2-yl]ethanenitrile and salicylaldehyde, chloroacetone, ethyl chloroacetate, or hydrazonoyl halid
Publikováno v:
Journal of Sulfur Chemistry. 26:21-31
2,3-Dihydro-1,3,4-thiadiazoles and triazolino[4,3- a]pyrimidines were synthesized in a good yields from reactions of hydrazonoyl halides with alkyl carbodithioate and pyrimidine-2-thione, respectively. All structures of the newly synthesized compound
Publikováno v:
Heteroatom Chemistry. 14:530-534
2-Benzyl- and 2-aryloxymethyl-3-amino-1-phenyl-pyrazolo[3,4-d]pyrimidine-4-ones 5a–f have been synthesized by reacting the corresponding arylacetylamino derivatives 3a–f with hydrazine hydrate. Thionation of compounds 5d–f by action of P2S5 in