Surgically resected sarcomatoid carcinoma of the lung: a nationwide retrospective study in 2010

Autor: Kaoru Kaseda, Keisuke Asakura, Yasushi Shintani, Jiro Okami, Shinichi Toyooka, Yukio Sato, Shun-Ichi Watanabe, Masayuki Chida, Hidemi Suzuki, Etsuo Miyaoka, Ichiro Yoshino, Hiroshi Date, The Japanese Joint Committee of Lung Cancer Registry

Publikováno v: BMC Cancer, Vol 24, Iss 1, Pp 1-14 (2024)

Abstract Background Sarcomatoid carcinoma of the lung is a rare histological type of non-small cell lung cancer with a poor prognosis. We aimed to investigate the clinicopathological characteristics and prognostic factors of surgically resected sarco

Externí odkaz: https://doaj.org/article/746bc39095554c20b9232bc0a831adec

Mechanism of ERBB2 gene overexpression by the formation of super-enhancer with genomic structural abnormalities in lung adenocarcinoma without clinically actionable genetic alterations

Autor: Syuzo Kaneko, Ken Takasawa, Ken Asada, Kouya Shiraishi, Noriko Ikawa, Hidenori Machino, Norio Shinkai, Maiko Matsuda, Mari Masuda, Shungo Adachi, Satoshi Takahashi, Kazuma Kobayashi, Nobuji Kouno, Amina Bolatkan, Masaaki Komatsu, Masayoshi Yamada, Mototaka Miyake, Hirokazu Watanabe, Akiko Tateishi, Takaaki Mizuno, Yu Okubo, Masami Mukai, Tatsuya Yoshida, Yukihiro Yoshida, Hidehito Horinouchi, Shun-Ichi Watanabe, Yuichiro Ohe, Yasushi Yatabe, Vassiliki Saloura, Takashi Kohno, Ryuji Hamamoto

Publikováno v: Molecular Cancer, Vol 23, Iss 1, Pp 1-17 (2024)

Abstract Background In an extensive genomic analysis of lung adenocarcinomas (LUADs), driver mutations have been recognized as potential targets for molecular therapy. However, there remain cases where target genes are not identified. Super-enhancers

Externí odkaz: https://doaj.org/article/41d2bbf4f86f4d019c77904a80b740d3

Eribulin versus S-1 as first or second-line chemotherapy to assess health-related quality of life and overall survival in HER2-negative metastatic breast cancer (RESQ study): a non-inferiority, randomised, controlled, open-label, phase 3 trialResearch in context

Autor: Masato Takahashi, Yuichiro Kikawa, Kosuke Kashiwabara, Naruto Taira, Tsuguo Iwatani, Kojiro Shimozuma, Shoichiro Ohtani, Tetsuhiro Yoshinami, Junichiro Watanabe, Masahiro Kashiwaba, Ken-ichi Watanabe, Masahiro Kitada, Koichi Sakaguchi, Yuko Tanabe, Tomohiko Aihara, Hirofumi Mukai

Publikováno v: EClinicalMedicine, Vol 74, Iss , Pp 102715- (2024)

Summary: Background: Eribulin prolongs overall survival (OS) of patients with human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (MBC), particularly in later chemotherapy (ChT) treatment. However, the health-related qua

Externí odkaz: https://doaj.org/article/1723e209a4034dd0b0e8a27d67cd3241

Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome‐wide association and whole genome sequencing analyses

Autor: Kouya Shiraishi, Atsushi Takahashi, Yukihide Momozawa, Yataro Daigo, Syuzo Kaneko, Takahisa Kawaguchi, Hideo Kunitoh, Shingo Matsumoto, Hidehito Horinouchi, Akiteru Goto, Takayuki Honda, Kimihiro Shimizu, Masahiro Torasawa, Daisuke Takayanagi, Motonobu Saito, Akira Saito, Yuichiro Ohe, Shun‐ichi Watanabe, Koichi Goto, Masahiro Tsuboi, Katsuya Tsuchihara, Sadaaki Takata, Tomomi Aoi, Atsushi Takano, Masashi Kobayashi, Yohei Miyagi, Kazumi Tanaka, Hiroyuki Suzuki, Daichi Maeda, Takumi Yamaura, Maiko Matsuda, Yoko Shimada, Takaaki Mizuno, Hiromi Sakamoto, Teruhiko Yoshida, Yasushi Goto, Tatsuya Yoshida, Taiki Yamaji, Makoto Sonobe, Shinichi Toyooka, Kazue Yoneda, Katsuhiro Masago, Fumihiro Tanaka, Megumi Hara, Nobuo Fuse, Satoshi S. Nishizuka, Noriko Motoi, Norie Sawada, Yuichiro Nishida, Kazuki Kumada, Kenji Takeuchi, Kozo Tanno, Yasushi Yatabe, Kuniko Sunami, Tomoyuki Hishida, Yasunari Miyazaki, Hidemi Ito, Mitsuhiro Amemiya, Hirohiko Totsuka, Haruhiko Nakayama, Tomoyuki Yokose, Kazuyoshi Ishigaki, Toshiteru Nagashima, Yoichi Ohtaki, Kazuhiro Imai, Ken Takasawa, Yoshihiro Minamiya, Kazuma Kobayashi, Kenichi Okubo, Kenji Wakai, Atsushi Shimizu, Masayuki Yamamoto, Motoki Iwasaki, Koichi Matsuda, Johji Inazawa, Yuichi Shiraishi, Hiroyoshi Nishikawa, Yoshinori Murakami, Michiaki Kubo, Fumihiko Matsuda, Yoichiro Kamatani, Ryuji Hamamoto, Keitaro Matsuo, Takashi Kohno

Publikováno v: Cancer Communications, Vol 44, Iss 2, Pp 287-293 (2024)

Externí odkaz: https://doaj.org/article/a4b8ea6db19942899046a4b6375483b8

Author Correction: Neutrophil-to-lymphocyte ratio is a prognostic factor reflecting immune condition of tumor microenvironment in squamous cell lung cancer

Autor: Kana Ohashi, Yukari Nishito, Hironori Fukuda, Ryoichi Sadahiro, Yukihiro Yoshida, Shun-ichi Watanabe, Noriko Motoi, Yukiko Sonobe, Hideaki Mizuno, Hiroyuki Tsunoda, Koichiro Tatsumi, Takuji Suzuki, Atsushi Ochiai, Kazunori Aoki

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)

Externí odkaz: https://doaj.org/article/fd499e780be446e9b37a6f9f0199d1e4