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Akademický článek

Potential endocrine-disrupting effects of iprodione via estrogen and androgen receptors: evaluation using in vitro assay and an in silico model

Autor: Ji-Yeon Yang, Jeong-Hyun Lim, Soo-Jin Park, Youmi Jo, Si Young Yang, Min-Kyoung Paik, So-Hye Hong

Publikováno v: Applied Biological Chemistry, Vol 67, Iss 1, Pp 1-8 (2024)

Abstract This study was conducted to provide evidence, using in vitro and in silico testing methods, regarding the adverse effects of iprodione, a representative dichlorophenyl dicarboxamide fungicide, on the endocrine system. In the present study, w

Externí odkaz: https://doaj.org/article/cf6b95f408ed4e9e9151439813b6cd37

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Akademický článek

Application of an Antioxidant Response Element–Nuclear Factor Erythroid 2 Luciferase Assay for Assessing the Skin Sensitization Potential of Agrochemicals

Autor: Ji-Yeon Yang, Soo-Jin Park, Ji-Young Shin, Jeong-Hyun Lim, Si Young Yang, Geun-Hwan Gil, So-Hye Hong

Publikováno v: Toxics, Vol 11, Iss 12, p 973 (2023)

The skin sensitization potential of agrochemicals can be assessed using laboratory methods such as the keratinocyte activation assay so that their use in regulatory toxicology might replace experimental animal testing. Here, we evaluated the skin sen

Externí odkaz: https://doaj.org/article/ac80ee494c4c43a1acb581735f111ef3

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Akademický článek

Skin Sensitization Evaluation of Carbon-Based Graphene Nanoplatelets

Autor: Sung-Hyun Kim, So-Hye Hong, Jin Hee Lee, Dong Han Lee, Kikyung Jung, Jun-Young Yang, Hyo-Sook Shin, JeongPyo Lee, Jayoung Jeong, Jae-Ho Oh

Publikováno v: Toxics, Vol 9, Iss 3, p 62 (2021)

Graphene nanoplatelets (GNPs) are one of the major types of carbon based nanomaterials that have different industrial and biomedical applications. There is a risk of exposure to GNP material in individuals involved in their large-scale production and

Externí odkaz: https://doaj.org/article/dce8db13bd7d427f9ec0b12e898d523b

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Akademický článek

Orally Administered 6:2 Chlorinated Polyfluorinated Ether Sulfonate (F-53B) Causes Thyroid Dysfunction in Rats

Autor: So-Hye Hong, Seung Hee Lee, Jun-Young Yang, Jin Hee Lee, Ki Kyung Jung, Ji Hyun Seok, Sung-Hee Kim, Ki Taek Nam, Jayoung Jeong, Jong Kwon Lee, Jae-Ho Oh

Publikováno v: Toxics, Vol 8, Iss 3, p 54 (2020)

The compound 6:2 chlorinated polyfluorinated ether sulfonate (F-53B), a replacement for perfluorooctanesulfonate (PFOS) in the electroplating industry, has been widely detected in numerous environmental matrices, human sera, and organisms. Due to reg

Externí odkaz: https://doaj.org/article/d66ab86cc9aa4029910d6b1a04261844

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ERdj5 protects goblet cells from endoplasmic reticulum stress-mediated apoptosis under inflammatory conditions

Autor: Hyunjin Jeong, Eun-Hye Hong, Jae-Hee Ahn, Jaewon Cho, Jae-Hyeon Jeong, Chae-Won Kim, Byung-Il Yoon, Ja Hyun Koo, Yun-Yong Park, Yoon Mee Yang, Takao Iwawaki, Bruce A. Vallance, Sun-Young Chang, Hyun-Jeong Ko

Publikováno v: Experimental & Molecular Medicine. 55:401-412

Endoplasmic reticulum stress is closely associated with the onset and progression of inflammatory bowel disease. ERdj5 is an endoplasmic reticulum-resident protein disulfide reductase that mediates the cleavage and degradation of misfolded proteins.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0146df5c5cec73e645086182663d72e7
https://doi.org/10.1038/s12276-023-00945-x

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