Zobrazeno 1 - 10
of 2 780
pro vyhledávání: '"So Hee Kwon"'
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-10 (2024)
Abstract Advances in functional studies on epigenetic regulators have disclosed the vital roles played by diverse histone lysine demethylases (KDMs), ranging from normal development to tumorigenesis. Most of the KDMs are Jumonji C domain-containing (
Externí odkaz:
https://doaj.org/article/c682454d3e114a1688c7fbe95fce4892
Autor:
Huonggiang Nguyen, Qingzhi Huang, Uijin Juang, Suhwan Gwon, Woohyeong Jung, Soohyeon Lee, Beomwoo Lee, So Hee Kwon, In Soo Kim, Jongsun Park, Seon-Hwan Kim
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionThe mutated in colorectal cancer (MCC) gene was initially identified as a candidate tumor suppressor gene in colorectal cancer, acting as a negative regulator of cell cycle progression. However, its functional roles in brain tumors, parti
Externí odkaz:
https://doaj.org/article/812ed5283ac0455c8cca390274ecd6b5
Publikováno v:
Journal of Yeungnam Medical Science, Vol 40, Iss Suppl, Pp S93-S97 (2023)
Thyroid storm is a life-threatening form of thyrotoxicosis and an endocrinological emergency. We present a case of thyroid storm in a patient with metastatic papillary thyroid cancer. A 67-year-old woman with a history of total thyroidectomy 4 years
Externí odkaz:
https://doaj.org/article/0678ad48352848ad86bb69bd2529074b
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 2648-2658 (2021)
Candida albicans is an opportunistic human fungal pathogen that exists in normal flora but can cause infection in immunocompromised individuals. The transition to pathogenic C. albicans requires a change of various gene expressions. Because histone-m
Externí odkaz:
https://doaj.org/article/665a9202b596483fb1b32a3bcf82ed99
Autor:
Dong Hoon Lee, Go Woon Kim, Jung Yoo, Sang Wu Lee, Yu Hyun Jeon, So Yeon Kim, Hyeok Gu Kang, Da-Hyun Kim, Kyung-Hee Chun, Junjeong Choi, So Hee Kwon
Publikováno v:
Cell Death and Disease, Vol 12, Iss 1, Pp 1-14 (2021)
Abstract Glioblastoma is the most lethal brain tumor and its pathogenesis remains incompletely understood. KDM4C is a histone H3K9 demethylase that contributes to epigenetic regulation of both oncogene and tumor suppressor genes and is often overexpr
Externí odkaz:
https://doaj.org/article/d0de556d57c8492ca33374883b95cc94
Publikováno v:
Cells, Vol 11, Iss 19, p 3161 (2022)
Histone deacetylase 8 (HDAC8) is a class I HDAC that catalyzes the deacetylation of histone and non-histone proteins. As one of the best-characterized isoforms, numerous studies have identified interacting partners of HDAC8 pertaining to diverse mole
Externí odkaz:
https://doaj.org/article/00d087e8be75476f8796f5f76a5c358d
Autor:
Hyunji Lee, Youngeun Hong, Quangdon Tran, Hyeonjeong Cho, Minhee Kim, Chaeyeong Kim, So Hee Kwon, SungJin Park, Jongsun Park, Jisoo Park
Publikováno v:
Journal of Ginseng Research, Vol 43, Iss 3, Pp 431-441 (2019)
Background: The efficacy of ginseng, the representative product of Korea, and its chemical effects have been well investigated. The ginsenoside RG3 has been reported to exhibit apoptotic, anticancer, and antidepressant-like effects. Methods: In this
Externí odkaz:
https://doaj.org/article/a61aa4f4d65c41678b3688b8e049fd4b
Autor:
Gyeyeong Kong, Hyunji Lee, Quangdon Tran, Chaeyeong Kim, Jisoo Park, So Hee Kwon, Seon-Hwan Kim, Jongsun Park
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/469889ca13e14d64aa67006cd597ef08
Autor:
Hyunji Lee, Minhee Kim, Seon-Hwan Kim, Quangdon Tran, Gyeyeong Kong, Chaeyeong Kim, So Hee Kwon, Jisoo Park, Jin Bong Park, Sungjin Park, Jongsun Park
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Alpha-Methylacyl-CoA racemase (AMACR), which was initially discovered as a prostate cancer marker, is critical for the chiral inversion mechanism of branched-chain fatty acids. However, the function of AMACR in brain tumors has not been investigated.
Externí odkaz:
https://doaj.org/article/304ae3d594a04d61b71c5be924df9ebf
Autor:
Gyeyeong Kong, Hyunji Lee, Quangdon Tran, Chaeyeong Kim, Nayoung Gong, Jisoo Park, So Hee Kwon, Seon-Hwan Kim, Jongsun Park
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Branched chain fatty acids perform very important functions in human diet and drug metabolism. they cannot be metabolized in mitochondria and are instead processed and degraded in peroxisomes due to the presence of methyl groups on the carbon chains.
Externí odkaz:
https://doaj.org/article/5a64c051bc3643268c376fc09800d457