Zobrazeno 1 - 10
of 118
pro vyhledávání: '"So, Choon Leng"'
Cellular geometry and epithelial-mesenchymal plasticity intersect with PIEZO1 in breast cancer cells
Autor:
Choon Leng So, Mélanie Robitaille, Francisco Sadras, Michael H. McCullough, Michael J. G. Milevskiy, Geoffrey J. Goodhill, Sarah J. Roberts-Thomson, Gregory R. Monteith
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract Differences in shape can be a distinguishing feature between different cell types, but the shape of a cell can also be dynamic. Changes in cell shape are critical when cancer cells escape from the primary tumor and undergo major morphologica
Externí odkaz:
https://doaj.org/article/d73be88b33ce498590a3f9946c02f12e
Autor:
So, Choon Leng1,2 (AUTHOR), Robitaille, Mélanie1 (AUTHOR), Sadras, Francisco1 (AUTHOR), McCullough, Michael H.3,4 (AUTHOR), Milevskiy, Michael J. G.5,6 (AUTHOR), Goodhill, Geoffrey J.3,7 (AUTHOR), Roberts-Thomson, Sarah J.1 (AUTHOR), Monteith, Gregory R.1 (AUTHOR) gregm@uq.edu.au
Publikováno v:
Communications Biology. 4/17/2024, Vol. 7 Issue 1, p1-14. 14p.
Autor:
Hui Jan Tan, Abdool Alleem Hj Shahren, Ching Soong Khoo, Chen Fei Ng, Wan Asyraf Wan Zaidi, Najma Kori, Petrick Periyasamy, Choon Leng Eu, Alvin Oliver Payus, Rozita Hod
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionAnxiety has been increasingly recognized as part of the psychosocial health issues in COVID-19 patients. However, the impact of this topic may be underestimated in low- and middle-income countries. This study aimed to estimate the prevale
Externí odkaz:
https://doaj.org/article/00f9c0ed7b354c5289b20b29d69655ce
Autor:
Shian-Ling Keng, Hajar Binti Mohd Salleh Sahimi, Lai Fong Chan, Luke Woon, Choon Leng Eu, Su Hua Sim, Man Kuan Wong
Publikováno v:
BMC Psychiatry, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Aim/background Even though dialectical behavior therapy (DBT) has received substantial empirical support in treating patients with borderline personality disorder (BPD), fewer studies have evaluated whether a brief DBT skills group may be ef
Externí odkaz:
https://doaj.org/article/3d0c50e3075e4d88b31aaa64783569f6
Autor:
Lai Fong Chan, Luke Sy-Cherng Woon, Nuur Asyikin Mohd Shukor, Choon Leng Eu, Nurazah Ismail, Song Jie Chin, Nik Ruzyanei Nik Jaafar, Azlin Baharudin
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
A significant proportion of patients with treatment-resistant depression do not attain functional recovery despite administration of multiple steps of pharmacotherapeutic strategies. This highlights the elusiveness of meeting unmet needs in existing
Externí odkaz:
https://doaj.org/article/140fbfe104084be5bbb2db48cc1da179
Publikováno v:
In Laboratory Investigation February 2020 100(2):199-206
Autor:
Alice Hui Li Bong, Trinh Hua, Choon Leng So, Amelia A. Peters, Mélanie Robitaille, Yin Yi Tan, Sarah J. Roberts-Thomson, Gregory R. Monteith
Publikováno v:
Cancers, Vol 14, Iss 19, p 4794 (2022)
Although breast cancer cells often exhibit both abnormal AKT signaling and calcium signaling, the association between these two pathways is unclear. Using a combination of pharmacological tools, siRNA and CRISPR/Cas9 gene silencing techniques, we inv
Externí odkaz:
https://doaj.org/article/2191a1f832de40b78cb9a6b67532dfa2
Autor:
Mélanie Robitaille, Shao Ming Chan, Amelia A. Peters, Limin Dai, Choon Leng So, Alice H. L. Bong, Francisco Sadras, Sarah J. Roberts-Thomson, Gregory R. Monteith
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 11, p 5867 (2022)
A remodeling of calcium homeostasis, including calcium influx via store-operated calcium entry (SOCE), is a feature of breast cancers. SOCE is critical to maintain calcium balance in the endoplasmic reticulum calcium store and is an important mechani
Externí odkaz:
https://doaj.org/article/9c9d03408e4447319133159a8d31556a
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Autor:
Iman Azimi, Mélanie Robitaille, Kaela Armitage, Choon Leng So, Michael J. G. Milevskiy, Korinne Northwood, Huai Fang Lim, Erik W. Thompson, Sarah J. Roberts-Thomson, Gregory R. Monteith
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9417 (2020)
Epithelial to mesenchymal transition (EMT) in cancer is important in therapeutic resistance and invasiveness. Calcium signaling is key to the induction of EMT in breast cancer cells. Although inhibition of specific calcium-permeable ion channels regu
Externí odkaz:
https://doaj.org/article/f76322cb5dd84b2985ee817b3544c7b4