The Idiopathic Pulmonary Fibrosis Clinical Research Network (IPFnet)

Autor: Neil R. MacIntyre, R. Richardson, F. Stokes, David A. Lynch, Eric L. Eisenstein, J. Rochon, Marilyn K. Glassberg, D. Dahlgren, DA Lynch, David A. Zisman, P. J. Wolters, W. Tate, T. Gentry-Bumpass, Francis Cordova, K. Kinser, Craig S. Glazer, L. Brewster, Joao A. de Andrade, T. Perez, Gary M. Hunninghake, T. Haram, J. Estrom, Bethany B. Moore, Maria L. Padilla, J. Pesarchick, G. Rahimova, Thomas V. Colby, Kelli L. Cain, B. Schmetter, E. Yow, E. Calahan, J. A. Golden, M. L. Han, Kevin K. Brown, K. Hwang, J. Kaur, K. Meiras, James P. Utz, J.L. Myers, J. De Andrade, Naresh P. Patel, H. Y. Reynolds, Barry H. Gross, M. Stewart, R. Wehrmann, N. A. Ettinger, John S. Sundy, Danielle Antin-Ozerkis, Mark P. Steele, S. R. White, Ivan O. Rosas, Q. Yang, M. Schwarz, Jonas Román, Imre Noth, N. Sandbo, I. Garic, G. Berhanu, Maryl Kreider, Eric S. White, K. Baumann, M. Kallay, H. Reynolds, E. Lyda, Galen B. Toews, Margaret L. Snyder, Ella E. Kazerooni, Aditi Satti, G.J. Criner, Irene Swift, J. Winsor, Simon L.F. Walsh, P. Debrosse, C. Holm, Richard C. Becker, K. Huang, John E. Fitzgerald, H. R. Collard, Mitchell A. Olman, Wendi R. Mason, Tedryl Gentry-Bumpass, Andrew H. Limper, Sara B. Calvert, Gail Weinmann, T. E. King, R. J. Kaner, A. Eller, A. Demersky, Mary E. Strek, Steven A. Sahn, Susan Lubell, Jennifer Hayes, Mary Beth Scholand, K. West, C. Bair, Graham Jones, Rhonda Roberts, M. Vey, James E. Chapman, Paul Hofmann, K. Le, Daniel A. Culver, Harold R. Collard, James P. Kiley, V. Monroy, L. Sardin, Joseph D. Zibrak, A. Sharlow, N. O'Banner, T. Colby, T. Thomas, Victor J. Thannickal, S. Ditta, M. Ingham, K. Chan, A. Snydsman, R. Greer, A. Johnson, John A. Belperio, M. Han, Ganesh Raghu, Kevin R. Flaherty, C. Matti, D. Hill, Craig E. Daniels, Kevin J. Anstrom, S. Maleckar, P. Lopez, D. Whelan, Paul J. Wolters, Joseph P. Lynch, Marvin I. Schwarz, M. Wang, Linda Davidson-Ray, William Lawson, P. Berry-Bell, Aamer Chughtai, S. Merli, Jeffrey A. Golden, Joseph A. Lasky, D. K. Hogarth, J. Walker, Joao deAndrade, R. Anderson, S. Ramey, James E. Loyd, Jay H. Ryu, T. Nguyen, Rex Edwards, R. Kidd, Lake Morrison, P. Dignacco, R. Jeffrey, Lisa Lancaster, Robert J. Kaner, Robert C. Hyzy, K. Bandong, Dolly Kervitsky, J. McClelland, Fernando J. Martinez, E. Simonet, E. Kagan, C. Brown, J. Lynch, A. Meredith, R. Perez, X. Tian, M. Rossman, R. Beci

Publikováno v: Chest. 148:1034-1042

BACKGROUND The National Heart, Lung, and Blood Institute-sponsored IPF Clinical Research Network (IPFnet) studies enrolled subjects with idiopathic pulmonary fibrosis (IPF) to evaluate drug therapies in treatment trials. An adjudication committee (AC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::51ebfbd141c37e6f6716ce4c7819bd32
https://doi.org/10.1378/chest.14-2889

In vivo analysis of cohesin architecture using FRET in the budding yeast Saccharomyces cerevisiae

Autor: Frank Uhlmann, Brian E. Snydsman, John Mc Intyre, Trisha N. Davis, Stefan Weitzer, Eric G D Muller

Publikováno v: The EMBO Journal

Cohesion between sister chromatids in eukaryotes is mediated by the evolutionarily conserved cohesin complex. Cohesin forms a proteinaceous ring, large enough to trap pairs of replicated sister chromatids. The circumference consists of the Smc1 and S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdfdb6cdee9b79c0c3fd2ff5b61205f7
https://doi.org/10.1038/sj.emboj.7601793

Assigning Function to Yeast Proteins by Integration of Technologies

Autor: Scott Anderson, Lars Malmström, Brian E. Snydsman, J. Derringer Aranda, Tony R. Hazbun, Bethany Fox, Phillip Bradley, David Baker, Eric G D Muller, Beth Graczyk, Trisha N. Davis, John R. Yates, Stanley Fields, Bryan A. Sundin, W. Hayes McDonald, Chun Hwei Chiu, Michael Riffle

Publikováno v: Molecular Cell. 12:1353-1365

Interpreting genome sequences requires the functional analysis of thousands of predicted proteins, many of which are uncharacterized and without obvious homologs. To assess whether the roles of large sets of uncharacterized genes can be assigned by t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d59f647fc8ae171750a161ef8f056a
https://doi.org/10.1016/s1097-2765(03)00476-3

Loss of a 20S proteasome activator in Saccharomyces cerevisiae downregulates genes important for genomic integrity, increases DNA damage, and selectively sensitizes cells to agents with diverse mechanisms of action

Autor: Ajay Pramanik, James Lukose, Kevin M. Doherty, Eric G D Muller, David Botstein, Ronald Charles, Brian E. Snydsman, Carol Wood Moore, Leah D. Pride

Publikováno v: G3: Genes|Genomes|Genetics

Cytoprotective functions of a 20S proteasome activator were investigated. Saccharomyces cerevisiae [Blm10][1] and human 20S proteasome activator 200 (PA200) are homologs. Comparative genome-wide analyses of untreated diploid cells lacking [Blm10][1]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7ca18c5baa6eede1a066a4c8cf93a7c
https://pubmed.ncbi.nlm.nih.gov/22908043

The Organization of the Core Proteins of the Yeast Spindle Pole BodyD⃞

Autor: Tom H. Giddings, Christine A. Niemann, Brian E. Snydsman, Eileen T. O'Toole, Dale W. Hailey, Trisha N. Davis, Eric G D Muller, Daniel R. Gestaut, Bryan A. Sundin, Isabella Novik

The spindle pole body (SPB) is the microtubule organizing center of Saccharomyces cerevisiae. Its core includes the proteins Spc42, Spc110 (kendrin/pericentrin ortholog), calmodulin (Cmd1), Spc29, and Cnm67. Each was tagged with CFP and YFP and their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ad23ac388174b906c918e59af79092
https://europepmc.org/articles/PMC1165416/