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Coxsackievirus infection induces direct pancreatic β-cell killing but poor anti-viral CD8+ T-cell responses.

Autor: Vecchio F; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Carré A; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Korenkov D; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Zhou Z; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Apaolaza P; Institute of Diabetes Research, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Tuomela S; Center for Infectious Medicine, Department of medicine Huddinge, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden., Burgos-Morales O; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Snowhite I; Diabetes Research Institute, Leonard Miller School of Medicine, University of Miami, FL, USA.; Department of Diabetes Immunology, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA., Perez-Hernandez J; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Brandao B; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Afonso G; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Halliez C; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Kaddis J; Department of Diabetes Immunology, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA.; Department of Diabetes and Cancer Discovery Science, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA., Kent SC; University of Massachusetts Medical Chan School, Diabetes Center of Excellence, Department of Medicine, Worcester, MA, USA., Nakayama M; Barbara Davis Center for Diabetes, University of Colorado School of Medicine, Aurora, CO, USA., Richardson SJ; Islet Biology Exeter (IBEx), Exeter Centre of Excellence for Diabetes Research (EXCEED), Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK., Vinh J; ESPCI Paris, PSL University, Spectrométrie de Masse Biologique et Protéomique, CNRS UMR8249, Paris, France., Verdier Y; ESPCI Paris, PSL University, Spectrométrie de Masse Biologique et Protéomique, CNRS UMR8249, Paris, France., Laiho J; Tampere University, Faculty of Medicine and Health Technology and Fimlab Laboratories, Tampere, Finland., Scharfmann R; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Solimena M; Paul Langerhans Institute, Technical University Dresden, Germany., Marinicova Z; Paul Langerhans Institute, Technical University Dresden, Germany., Bismuth E; Assistance Publique Hôpitaux de Paris, Service d'Endocrinologie Pédiatrique, Robert Debré Hospital, Paris, France., Lucidarme N; Assistance Publique Hôpitaux de Paris, Service de Pédiatrie, Jean Verdier Hospital, Bondy, France., Sanchez J; Department of Pediatrics, Division of pediatric Endocrinology, Leonard Miller School of Medicine, University of Miami, FL, USA., Bustamante C; Department of Pediatrics, Division of pediatric Endocrinology, Leonard Miller School of Medicine, University of Miami, FL, USA., Gomez P; Department of Pediatrics, Division of pediatric Endocrinology, Leonard Miller School of Medicine, University of Miami, FL, USA., Buus S; Panum Institute, Department of International Health, Immunology and Microbiology, Copenhagen, Denmark., You S; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France.; Indiana Biosciences Research Institute, Indianapolis, IN, USA., Pugliese A; Diabetes Research Institute, Leonard Miller School of Medicine, University of Miami, FL, USA.; Department of Diabetes Immunology, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA., Hyoty H; Tampere University, Faculty of Medicine and Health Technology and Fimlab Laboratories, Tampere, Finland., Rodriguez-Calvo T; Institute of Diabetes Research, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Flodstrom-Tullberg M; Center for Infectious Medicine, Department of medicine Huddinge, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden., Mallone R; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France.; Indiana Biosciences Research Institute, Indianapolis, IN, USA.; Assistance Publique Hôpitaux de Paris, Service de Diabétologie et Immunologie Clinique, Cochin Hospital, Paris, France.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Aug 21. Date of Electronic Publication: 2023 Aug 21.