A novel method of screening combinations of angiostatics identifies bevacizumab and temsirolimus as synergistic inhibitors of glioma-induced angiogenesis.

Autor: Dorrell MI; Department of Biology, Point Loma Nazarene University, San Diego, CA, United States of America., Kast-Woelbern HR; Department of Biology, Point Loma Nazarene University, San Diego, CA, United States of America., Botts RT; Department of Mathematical, Information, and Computer Sciences, Point Loma Nazarene University, San Diego, CA, United States of America., Bravo SA; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Tremblay JR; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Giles S; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Wada JF; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Alexander M; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Garcia E; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Villegas G; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Booth CB; Department of Mathematical, Information, and Computer Sciences, Dr. Ryan Bott's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Purington KJ; Department of Mathematical, Information, and Computer Sciences, Dr. Ryan Bott's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Everett HM; Department of Mathematical, Information, and Computer Sciences, Dr. Ryan Bott's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Siles EN; Department of Mathematical, Information, and Computer Sciences, Dr. Ryan Bott's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Wheelock M; Department of Mathematical, Information, and Computer Sciences, Dr. Ryan Bott's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Silva JA; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Fortin BM; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Lowey CA; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Hale AL; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Kurz TL; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Rusing JC; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Goral DM; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Thompson P; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Johnson AM; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Elson DJ; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Tadros R; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Gillette CE; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Coopwood C; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Rausch AL; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America., Snowbarger JM; Department of Biology, Dr. Michael Dorrell's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.; Department of Biology, Dr. Heidi R. Kast-Woelbern's Lab, Point Loma Nazarene University, San Diego, CA, United States of America.

Publikováno v: PloS one [PLoS One] 2021 Jun 02; Vol. 16 (6), pp. e0252233. Date of Electronic Publication: 2021 Jun 02 (Print Publication: 2021).