pGluAbeta increases accumulation of Abeta in vivo and exacerbates its toxicity

Autor: Sofola-Adesakin, O., Khericha, M., Snoeren, I., Tsuda, L., Partridge, L.

Publikováno v: Acta Neuropathol Commun

Several species of beta-amyloid peptides (Abeta) exist as a result of differential cleavage from amyloid precursor protein (APP) to yield various C-terminal Abeta peptides. Several N-terminal modified Abeta peptides have also been identified in Alzhe

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https://hdl.handle.net/21.11116/0000-000B-6EC5-C

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pGluAβ increases accumulation of Aβ in vivo and exacerbates its toxicity.

Autor: Sofola-Adesakin O; Institute of Healthy Ageing, and G.E.E., University College London, Darwin Building, Gower Street, London, WC1E 6BT, UK., Khericha M; Institute of Healthy Ageing, and G.E.E., University College London, Darwin Building, Gower Street, London, WC1E 6BT, UK.; Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Straße 9B, 50931, Cologne, Germany., Snoeren I; Institute of Healthy Ageing, and G.E.E., University College London, Darwin Building, Gower Street, London, WC1E 6BT, UK.; Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Straße 9B, 50931, Cologne, Germany., Tsuda L; Center for Development of Advanced Medicine for Dementia (CAMD), National Center for Geriatrics and Gerontology (NCGG), Obu, Aichi, Japan., Partridge L; Institute of Healthy Ageing, and G.E.E., University College London, Darwin Building, Gower Street, London, WC1E 6BT, UK. l.partridge@ucl.ac.uk.; Max Planck Institute for Biology of Ageing, Joseph-Stelzmann-Straße 9B, 50931, Cologne, Germany. l.partridge@ucl.ac.uk.

Publikováno v: Acta neuropathologica communications [Acta Neuropathol Commun] 2016 Oct 07; Vol. 4 (1), pp. 109. Date of Electronic Publication: 2016 Oct 07.