Zobrazeno 1 - 10
of 33
pro vyhledávání: '"SnoRNA processing"'
Autor:
Stefanie Gerstberger, Cindy Meyer, Sigi Benjamin-Hong, Joe Rodriguez, Daniel Briskin, Claudia Bognanni, Kimberly Bogardus, Hermann Steller, Thomas Tuschl
Publikováno v:
Cell Reports, Vol 21, Iss 3, Pp 758-772 (2017)
Non-coding RNA biogenesis in higher eukaryotes has not been fully characterized. Here, we studied the Drosophila melanogaster Rexo5 (CG8368) protein, a metazoan-specific member of the DEDDh 3′-5′ single-stranded RNA exonucleases, by genetic, bioc
Externí odkaz:
https://doaj.org/article/06c6c57008cb4839b64703f881b49613
Publikováno v:
FEBS Lett
tRNA(His) guanylyltransferase (Thg1) specifies eukaryotic tRNA(His) identity by catalyzing a 3’ to 5’ non-Watson Crick (WC) addition of guanosine to the 5’-end of tRNA(His). Thg1 family enzymes in Archaea and Bacteria, called Thg1-like-proteins
Autor:
Hermann Steller, Joe Rodriguez, Cindy Meyer, Daniel Briskin, Sigi Benjamin-Hong, Stefanie Gerstberger, Thomas Tuschl, Claudia Bognanni, Kimberly Bogardus
Publikováno v:
Cell Reports, Vol 21, Iss 3, Pp 758-772 (2017)
Non-coding RNA biogenesis in higher eukaryotes has not been fully characterized. Here, we studied the Drosophila melanogaster Rexo5 (CG8368) protein, a metazoan-specific member of the DEDDh 3′-5′ single-stranded RNA exonucleases, by genetic, bioc
Autor:
Christian Trahan, Sebastian Pechmann, Ben Montpetit, Louis Gendron, Lisbeth-Carolina Aguilar, Marlene Oeffinger, Biplab C. Paul, Taylor Reiter, Arvind Arul Nambi Rajan, Rachel Montpetit
Publikováno v:
Nucleic Acids Research
RNA-binding proteins (RBPs) are key mediators of RNA metabolism. Whereas some RBPs exhibit narrow transcript specificity, others function broadly across both coding and non-coding RNAs. Here, in Saccharomyces cerevisiae, we demonstrate that changes i
Autor:
Ling-Ling Chen, Yu-Hang Xing
Publikováno v:
Critical Reviews in Biochemistry and Molecular Biology. 53:596-606
Small nucleolar RNAs (snoRNAs) are a family of conserved nuclear RNAs that function in the modification of small nuclear RNAs (snRNAs) or ribosomal RNAs (rRNAs), or participate in the processing of rRNAs during ribosome subunit maturation. Eukaryotic
Autor:
Tirza Doniger, Shulamit Michaeli, Smadar Cohen-Chalamish, Nikolay G. Kolev, Elisabetta Ullu, Nasreen Hag Yahia, Sachin Kumar Gupta, Christian Tschudi, Hiba Waldman Ben-Asher, Liat Kolet, Vaibhav Chikne, K. Shanmugha Rajan, Ron Unger
Publikováno v:
Journal of Molecular Biology. 429:3301-3318
The parasite Trypanosoma brucei is the causative agent of African sleeping sickness and is known for its unique RNA processing mechanisms that are common to all the kinetoplastidea including Leishmania and Trypanosoma cruzi. Trypanosomes possess two
Publikováno v:
Blood. 136:40-40
Germline mutations in the DEAD-box RNA helicase gene DDX41 cause inherited susceptibility to Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML). These patients have normal hematopoietic indices into adulthood and present with MDS at a me
Autor:
Kayo Yamada, Akinori Endo, Motoharu Ono, Angus I. Lamond, Michelle S. Scott, Geoffrey J. Barton
Publikováno v:
Nucleic Acids Research
Small nucleolar RNAs (snoRNAs) function mainly as guides for the post-transcriptional modification of ribosomal RNAs (rRNAs). In recent years, several studies have identified a wealth of small fragments (
Autor:
Quinn M. Mitrovich, Brian B. Tuch, Christine Guthrie, Alexander D. Johnson, Francisco M. De La Vega
Publikováno v:
Science. 330:838-841
Kicking Out Introns Many genes in eukaryotes contain introns that must be removed from the messenger RNA for proper gene function. Humans have on average eight introns per gene, whereas more than 90% of the genes in the yeast species Saccharomyces ce
Autor:
Ludivine Wacheul, Michael P. Terns, Hui Qiu, Denis L. J. Lafontaine, Jelena Jakovljevic, John L. Woolford, Rebecca M. Terns, Adam C. Berger, Anita H. Corbett, Julia Eifert, Marc Thiry
Publikováno v:
Molecular and Cellular Biology. 28:3686-3699
Small nucleolar RNAs (snoRNAs) orchestrate the modification and cleavage of pre-rRNA and are essential for ribosome biogenesis. Recent data suggest that after nucleoplasmic synthesis, snoRNAs transiently localize to the Cajal body (in plant and anima