Recombinant human proteoglycan 4 lowers inflammation and atherosclerosis susceptibility in female low-density lipoprotein receptor knockout mice.

Autor: Hoekstra M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.; Division of Systems Pharmacology and Pharmacy, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.; Pharmacy Leiden, Leiden, The Netherlands., Snip OSC; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.; Division of Systems Pharmacology and Pharmacy, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Janusz P; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Bernabé Kleijn MNA; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Truitt ER 3rd; Lμbris Biopharma, Naples, Florida, USA., Sullivan BD; Lμbris Biopharma, Naples, Florida, USA., Schmidt TA; Biomedical Engineering Department, University of Connecticut Health Center, Farmington, Connecticut, USA., Jay GD; Department of Emergency Medicine, Warren Alpert Medical School and Division of Biomedical Engineering, School of Engineering, Brown University, Providence, Rhode Island, USA., Van Eck M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.; Division of Systems Pharmacology and Pharmacy, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands.; Pharmacy Leiden, Leiden, The Netherlands.

Publikováno v: The Journal of physiology [J Physiol] 2024 May; Vol. 602 (9), pp. 1939-1951. Date of Electronic Publication: 2024 Apr 12.

Apolipoprotein A1 deficiency in mice primes bone marrow stem cells for T cell lymphopoiesis.

Autor: Ouweneel AB; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333CC Leiden, The Netherlands., Reiche ME; Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centers, University of Amsterdam, 1105AZ Amsterdam, The Netherlands., Snip OSC; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333CC Leiden, The Netherlands., Wever R; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333CC Leiden, The Netherlands., van der Wel EJ; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333CC Leiden, The Netherlands., Schaftenaar FH; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333CC Leiden, The Netherlands., Kauerova S; Laboratory for Atherosclerosis Research, Institute for Clinical and Experimental Medicine, 12111 Prague, Czech Republic., Lutgens E; Department of Medical Biochemistry, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centers, University of Amsterdam, 1105AZ Amsterdam, The Netherlands., Van Eck M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333CC Leiden, The Netherlands., Hoekstra M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, 2333CC Leiden, The Netherlands.

Publikováno v: Journal of cell science [J Cell Sci] 2022 Mar 01; Vol. 135 (5). Date of Electronic Publication: 2021 Nov 16.

Hypercholesterolemia impairs megakaryopoiesis and platelet production in scavenger receptor BI knockout mice.

Autor: Ouweneel AB; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands. Electronic address: a.b.ouweneel@lacdr.leidenuniv.nl., Hoekstra M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands., van der Wel EJ; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands., Schaftenaar FH; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands., Snip OSC; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands., Hassan J; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands., Korporaal SJA; Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands., Van Eck M; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands.

Publikováno v: Atherosclerosis [Atherosclerosis] 2019 Mar; Vol. 282, pp. 176-182. Date of Electronic Publication: 2018 Sep 22.