Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Snezana Vasiljevic"'
Autor:
Anna-Janina Behrens, Snezana Vasiljevic, Laura K. Pritchard, David J. Harvey, Rajinder S. Andev, Stefanie A. Krumm, Weston B. Struwe, Albert Cupo, Abhinav Kumar, Nicole Zitzmann, Gemma E. Seabright, Holger B. Kramer, Daniel I.R. Spencer, Louise Royle, Jeong Hyun Lee, Per J. Klasse, Dennis R. Burton, Ian A. Wilson, Andrew B. Ward, Rogier W. Sanders, John P. Moore, Katie J. Doores, Max Crispin
Publikováno v:
Cell Reports, Vol 14, Iss 11, Pp 2695-2706 (2016)
The HIV-1 envelope glycoprotein trimer is covered by an array of N-linked glycans that shield it from immune surveillance. The high density of glycans on the trimer surface imposes steric constraints limiting the actions of glycan-processing enzymes,
Externí odkaz:
https://doaj.org/article/e2e8bb16346745dfaa8a226260faf0dc
Autor:
Laura K. Pritchard, Snezana Vasiljevic, Gabriel Ozorowski, Gemma E. Seabright, Albert Cupo, Rajesh Ringe, Helen J. Kim, Rogier W. Sanders, Katie J. Doores, Dennis R. Burton, Ian A. Wilson, Andrew B. Ward, John P. Moore, Max Crispin
Publikováno v:
Cell Reports, Vol 11, Iss 10, Pp 1604-1613 (2015)
A highly glycosylated, trimeric envelope glycoprotein (Env) mediates HIV-1 cell entry. The high density and heterogeneity of the glycans shield Env from recognition by the immune system, but paradoxically, many potent broadly neutralizing antibodies
Externí odkaz:
https://doaj.org/article/d4e2a5d17a8b4ea0bb85403c8f1533de
Publikováno v:
Analytical and Bioanalytical Chemistry
Structural determination of N-glycans by mass spectrometry is ideally performed by negative ion collision-induced dissociation because the spectra are dominated by cross-ring fragments leading to ions that reveal structural details not available by m
Autor:
Raymond A. Dwek, Nicole Zitzmann, J. L. Kiappes, Juliane Brun, Anu V. Chandran, Mario Hensen, Snezana Vasiljevic, Michelle L. Hill, Weston B. Struwe, Bevin Gangadharan, Dominic S. Alonzi
Severe acute respiratory syndrome coronavirus 2 is the causative pathogen of the COVID-19 pandemic which as of Nov 15, 2020 has claimed 1,319,946 lives worldwide. Vaccine development focuses on the viral trimeric spike glycoprotein as the main target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c85d2b4d6b65655afe1ac36ffbee9ebe
https://doi.org/10.1101/2020.11.16.384594
https://doi.org/10.1101/2020.11.16.384594
Autor:
Joel D. Allen, Marit J. van Gils, Snezana Vasiljevic, Yasunori Watanabe, Alessio D'addabbo, Max Crispin, Christopher A. Cottrell, Gemma E. Seabright, Anna-Janina Beherns, David J. Harvey, Allison Maker, Andrew B. Ward, Rogier W. Sanders, Natalia de Val
Publikováno v:
bioRxiv
SUMMARYNumerous broadly neutralizing antibodies (bnAbs) have been identified that target the glycans of the HIV-1 envelope spike. Neutralization breadth is notable given that glycan processing can be substantially influenced by the presence or absenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bfa9c7f1c4dbf0292fb61c8a2c475ea
Autor:
Alessio D'addabbo, Anna-Janina Behrens, David Harvey, Snezana Vasiljevic, Thomas M. Polveroni, Nicole Scaringi, Marit J. van Gils, Andrew B. Ward, Christopher A. Cottrell, Allison Maker, Gemma E. Seabright, Rogier W. Sanders, Yasunori Watanabe, Max Crispin, Joel D. Allen, Natalia de Val
Publikováno v:
Structure(London, England:1993)
Structure (London, England, 28(8), 897-909.e6. Cell Press
Structure (London, England, 28(8), 897-909.e6. Cell Press
Summary Numerous broadly neutralizing antibodies (bnAbs) have been identified that target the glycans of the HIV-1 envelope spike. Neutralization breadth is notable given that glycan processing can be substantially influenced by the presence or absen
Autor:
Yasunori Watanabe, Helen M. E. Duyvesteyn, Max Crispin, Snezana Vasiljevic, Weston B. Struwe, Joel D. Allen, Gemma E. Seabright, Katie J. Doores
Publikováno v:
Analytical chemistry. 90(12)
The development of domain-exchanged antibodies offers a route to high-affinity targeting to clustered multivalent epitopes, such as those associated with viral infections and many cancers. One strategy to generate these antibodies is to introduce mut
Publikováno v:
Journal of the American Society for Mass Spectrometry
Extracted arrival time distributions of negative ion CID-derived fragments produced prior to traveling-wave ion mobility separation were evaluated for their ability to provide structural information on N-linked glycans. Fragmentation of high-mannose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82ee4c0b5c270a00bcde75948368be6
https://eprints.soton.ac.uk/418792/
https://eprints.soton.ac.uk/418792/
Autor:
Helen J. Kim, Laura K. Pritchard, John P. Moore, Katie J. Doores, Gabriel Ozorowski, Dennis R. Burton, Max Crispin, Rajesh P. Ringe, Ian A. Wilson, Rogier W. Sanders, Albert Cupo, Gemma E. Seabright, Snezana Vasiljevic, Andrew B. Ward
Publikováno v:
Cell Reports, Vol 11, Iss 10, Pp 1604-1613 (2015)
Cell reports, 11(10), 1604-1613. Cell Press
Cell reports, 11(10), 1604-1613. Cell Press
SummaryA highly glycosylated, trimeric envelope glycoprotein (Env) mediates HIV-1 cell entry. The high density and heterogeneity of the glycans shield Env from recognition by the immune system, but paradoxically, many potent broadly neutralizing anti
Autor:
Kevin P. Guay, Roberta Ibba, J.L. Kiappes, Snežana Vasiljević, Francesco Bonì, Maria De Benedictis, Ilaria Zeni, James D. Le Cornu, Mario Hensen, Anu V. Chandran, Anastassia L. Kantsadi, Alessandro T. Caputo, Juan I. Blanco Capurro, Yusupha Bayo, Johan C. Hill, Kieran Hudson, Andrea Lia, Juliane Brun, Stephen G. Withers, Marcelo Martí, Emiliano Biasini, Angelo Santino, Matteo De Rosa, Mario Milani, Carlos P. Modenutti, Daniel N. Hebert, Nicole Zitzmann, Pietro Roversi
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107919- (2023)
Summary: Misfolded glycoprotein recognition and endoplasmic reticulum (ER) retention are mediated by the ER glycoprotein folding quality control (ERQC) checkpoint enzyme, UDP-glucose glycoprotein glucosyltransferase (UGGT). UGGT modulation is a promi
Externí odkaz:
https://doaj.org/article/65e937022caf475ebc2513beca012f73