Výsledky vyhledávání - "Snezana Djordevic"

Ablation of Neuropilin 1 from glioma-associated microglia and macrophages slows tumor progression

Autor: David L. Selwood, Jeremy T. Miyauchi, Kenneth R. Shroyer, Jillian C. Nissen, Danling Chen, Matthew Choi, Snezana Djordevic, Ian Zachary, Stella E. Tsirka

Publikováno v: Oncotarget

Gliomas are the most commonly diagnosed primary tumors of the central nervous system (CNS). Median times of survival are dismal regardless of the treatment approach, underlying the need to develop more effective therapies. Modulation of the immune sy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8211df9e85abbe780c7f318662eafe87
https://pubmed.ncbi.nlm.nih.gov/26755653

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N-terminal modification of VEGF-A C terminus-derived peptides delineates structural features involved in neuropilin-1 binding and functional activity

Autor: David L. Selwood, Rehan Aqil, Chris Chapman, Ashley Jarvis, Snezana Djordevic, Paul Frankel, A. W. Edith Chan, Basil Hartzoulakis, Haiyan Jia, Shaheda Shaikh, Lili Cheng, John Martin, Antonina Frolov, Ian M. Evans, Ian Zachary

Publikováno v: Chembiochem : a European journal of chemical biology. 15(8)

The interaction between VEGF-A and its neuropilin (NRP) receptors mediates a number of important biological effects. NRP1 and the related molecule NRP2 are widely expressed on multiple tumour types and throughout the tumour vasculature, and are emerg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afde498cebb08a6b66b23fd8fed7d74b
https://pubmed.ncbi.nlm.nih.gov/24771685

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Design and development of novel non-peptide agonists at NPR-C

Autor: David L. Selwood, Michela I. Simone, Roberta J. Worthington, Paul J. Gane, Adrian J. Hobbs, Snezana Djordevic, Filipa Mota Quinteiro, Anne-Sophie Rebstock

Publikováno v: BMC Pharmacology

BackgroundEndothelium-derived C-type natriuretic peptide (CNP)possesses cytoprotective and anti-atherogenic functionsthat regulate vascular tone and smooth-muscle relaxa-tion and might be key in protecting against ischaemia-reperfusion injury [1]. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7eaeca572a379f80c2df547c5636c12
http://europepmc.org/articles/PMC3363250

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