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Akademický článek
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Publikováno v:
BMC Evolutionary Biology, Vol 12, Iss 1, p 99 (2012)
Abstract Background The study of biological networks and how they have evolved is fundamental to our understanding of the cell. By investigating how proteins of different ages are connected in the protein interaction network, one can infer how that n
Externí odkaz:
https://doaj.org/article/59ffcd92a2054733b60bb5f26186b37e
Publikováno v:
BMC Bioinformatics, Vol 11, Iss 1, p 86 (2010)
Abstract Background Homology is a crucial concept in comparative genomics. The algorithm probably most widely used for homology detection in comparative genomics, is BLAST. Usually a stringent score cutoff is applied to distinguish putative homologs
Externí odkaz:
https://doaj.org/article/de8797660b5d48f7828b4113fadf9d39
Publikováno v:
BMC Evolutionary Biology, Vol 8, Iss 1, p 337 (2008)
Abstract Background Thanks to recent high coverage mass-spectrometry studies and reconstructed protein complexes, we are now in an unprecedented position to study the evolution of biological systems. Gene duplications, known to be a major source of i
Externí odkaz:
https://doaj.org/article/ded5f4196cb54e7aa55947839f638ef1
Autor:
Snel Berend, Boekhorst Jos
Publikováno v:
BMC Bioinformatics, Vol 8, Iss 1, p 356 (2007)
Abstract Background Homology is a key concept in both evolutionary biology and genomics. Detection of homology is crucial in fields like the functional annotation of protein sequences and the identification of taxon specific genes. Basic homology sea
Externí odkaz:
https://doaj.org/article/e994af37a1264eca9db681c212db8a03
Publikováno v:
BMC Bioinformatics, Vol 8, Iss 1, p 83 (2007)
Abstract Background Orthology is one of the cornerstones of gene function prediction. Dividing the phylogenetic relations between genes into either orthologs or paralogs is however an oversimplification. Already in two-species gene-phylogenies, the c
Externí odkaz:
https://doaj.org/article/1a21d3c4f7db4feb87517f1fdab8ea7a
Publikováno v:
Biology Direct, Vol 1, Iss 1, p 8 (2006)
Abstract Background Peroxisomes are ubiquitous eukaryotic organelles involved in various oxidative reactions. Their enzymatic content varies between species, but the presence of common protein import and organelle biogenesis systems support a single
Externí odkaz:
https://doaj.org/article/3f4d908ab7a04af49a4302f1f48932a5
Publikováno v:
BMC Genomics, Vol 7, Iss 1, p 10 (2006)
Abstract Background The massive scale of microarray derived gene expression data allows for a global view of cellular function. Thus far, comparative studies of gene expression between species have been based on the level of expression of the gene ac
Externí odkaz:
https://doaj.org/article/97f4064e9f294e5abe68436c0146d3e6
Publikováno v:
In Current Biology 18 May 2020 30(10):R589-R602
Akademický článek
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