Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sneha Ratnapriya"'
Autor:
Durgadevi Parthasarathy, Karunakar Reddy Pothula, Sneha Ratnapriya, Héctor Cervera Benet, Ruth Parsons, Xiao Huang, Salam Sammour, Katarzyna Janowska, Miranda Harris, Joseph Sodroski, Priyamvada Acharya, Alon Herschhorn
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract HIV-1 envelope glycoproteins (Envs) of most primary HIV-1 strains exist in closed conformation and infrequently sample open states, limiting access to internal epitopes. Thus, immunogen design aims to mimic the closed Env conformation as pre
Externí odkaz:
https://doaj.org/article/586e2ac8dde84379b0e08159c9302824
Autor:
Shamim Ahmed, Durgadevi Parthasarathy, Rachael Newhall, Tashina Picard, Morgainne Aback, Sneha Ratnapriya, William Arndt, Widaliz Vega-Rodriguez, Natalie M. Kirk, Yuying Liang, Alon Herschhorn
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract An effective human immunodeficiency virus type I (HIV-1) vaccine that robustly elicits broadly neutralizing antibodies (bnAbs) against HIV-1 envelope glycoproteins (Envs) to block viral entry is still not available. Thus, identifying trigger
Externí odkaz:
https://doaj.org/article/b0bfdd08ba3f43279f53917824cf0464
Autor:
Keerti, Narendra Kumar Yadav, Sumit Joshi, Sneha Ratnapriya, Amogh Anant Sahasrabuddhe, Anuradha Dube
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 56, Iss 1, Pp 163-171 (2023)
Background: Available therapeutics for visceral leishmaniasis (VL), a deadly parasitic infection, are usually associated with inadequate efficacy and adverse aftereffects. Further, the primary site of Leishmania parasite are host macrophages resultin
Externí odkaz:
https://doaj.org/article/ec850d1504724b70bad26fcb303715e0
Autor:
Daniel S. Shin, Sneha Ratnapriya, Creel Ng Cashin, Lucy F. Kuhn, Rod A. Rahimi, Robert M. Anthony, James J. Moon
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112839- (2023)
Summary: Self-antigen-specific T cells are prevalent in the mature adaptive immune system but are regulated through multiple mechanisms of tolerance. However, inflammatory conditions such as tissue injury may allow these T cells to break tolerance an
Externí odkaz:
https://doaj.org/article/789163fd0bd44ba380335678039c2022
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100133- (2020)
Summary: HIV-1 envelope glycoproteins (Envs) bind to CD4 receptor and CCR5/CXCR4 coreceptor and mediate viral entry (Feng et al., 1996; Herschhorn et al., 2016, 2017; Kwong et al., 1998). HIV-1 Envs are the sole target of neutralizing antibodies and
Externí odkaz:
https://doaj.org/article/f87dc511342140559129cba1af3deca2
Autor:
null Keerti, Narendra Kumar Yadav, Sumit Joshi, Sneha Ratnapriya, Amogh Anant Sahasrabuddhe, Anuradha Dube
Publikováno v:
Journal of Microbiology, Immunology and Infection. 56:163-171
Available therapeutics for visceral leishmaniasis (VL), a deadly parasitic infection, are usually associated with inadequate efficacy and adverse aftereffects. Further, the primary site of Leishmania parasite are host macrophages resulting in comprom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c16537faef2e00164d41c912eed8dcd7
https://doi.org/10.1016/j.jmii.2022.06.003
https://doi.org/10.1016/j.jmii.2022.06.003
Autor:
Sneha Ratnapriya, Anthony R. Braun, Héctor Cervera Benet, Danielle Carlson, Shilei Ding, Carolyn N. Paulson, Neeraj Mishra, Jonathan N. Sachs, Courtney C. Aldrich, Andrés Finzi, Alon Herschhorn
Publikováno v:
ACS Infectious Diseases. 8:2045-2058
The entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into host cells requires binding of the viral spike glycoprotein to the angiotensin-converting enzyme 2 (ACE2) receptor, which triggers subsequent conformational changes to fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5346e498769dac3793e3a1d2b9a34554
https://doi.org/10.1021/acsinfecdis.1c00658
https://doi.org/10.1021/acsinfecdis.1c00658
Autor:
Daniel S. Shin, Sneha Ratnapriya, Creel Ng Cashin, Lucy F. Kuhn, Rod A. Rahimi, Robert M. Anthony, James J. Moon
Publikováno v:
bioRxiv
SummarySelf antigen-specific T cells are prevalent in the mature adaptive immune system, but are regulated through multiple mechanisms of tolerance. However, inflammatory conditions such as tissue injury may provide these T cells with an opportunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82aa25ad1b1914d40f0d888ebbb6dc32
https://europepmc.org/articles/PMC9934659/
https://europepmc.org/articles/PMC9934659/
Publikováno v:
BioMed Research International, Vol 2021 (2021)
Immunotherapy, a treatment based on host immune system activation, has been shown to provide a substitute for marginally effective conventional chemotherapy in controlling visceral leishmaniasis (VL), the deadliest form of leishmaniasis. As the major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d9462ad5e816a238d739d2907cda05
https://doi.org/10.1155/2021/8845826
https://doi.org/10.1155/2021/8845826
Publikováno v:
ACS Infect Dis
Human immunodeficiency virus (HIV-1) envelope glycoproteins (Envs) are a main focus of immunogen design and vaccine development. Broadly neutralizing antibodies (bnAbs) against HIV-1 Envs target conserved epitopes and neutralize multiple HIV-1 viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf86281d4dd505db82109c582d42e152
https://pubmed.ncbi.nlm.nih.gov/34006087
https://pubmed.ncbi.nlm.nih.gov/34006087