Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sneha R Sagar"'
Publikováno v:
Heliyon, Vol 9, Iss 5, Pp e15644- (2023)
Angiotensin converting enzyme 2 (ACE2) is a homolog of ACE (a transmembrane bound dipeptidyl peptidase enzyme). ACE2 converts angiotensinogen to the heptapeptide angiotensin-(1–7). ACE2 and its product, angiotensin-(1–7), have counteracting effec
Externí odkaz:
https://doaj.org/article/1172f2967e8a4510882b9ea64d02e2df
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:13778-13798
Diabetes is one of the leading causes of death globally as per World Health Organization 2019. To cope up with side effects of current diabetes therapy, researchers have found several novel targets for the treatment of diabetes. Currently, dipeptidyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49a1d39ca97d9ad65ba9586f19cf4edd
https://doi.org/10.1080/07391102.2021.1994876
https://doi.org/10.1080/07391102.2021.1994876
Publikováno v:
Advances in Traditional Medicine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30957efc5923d05a7a3a2fcb10853a00
https://doi.org/10.1007/s13596-022-00646-2
https://doi.org/10.1007/s13596-022-00646-2
Publikováno v:
Chemical Data Collections. 41:100923
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afb7ac53815e7415aa3f52aac3fd40dd
https://doi.org/10.1016/j.cdc.2022.100923
https://doi.org/10.1016/j.cdc.2022.100923
Autor:
Hemantkumar D. Ingawale, Kamala K. Vasu, Dhaivat H. Pandya, Milee Agarwal, Jayesh A. Sharma, Sneha R. Sagar
Publikováno v:
Current Bioactive Compounds. 14:254-263
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5c7fa25b3585a4e5c5ab58955e2b37a
https://doi.org/10.2174/1573407213666170329131557
https://doi.org/10.2174/1573407213666170329131557
Autor:
Rajesh D. Das, Kamala K. Vasu, Nirupa B. Panchal, Sneha R. Sagar, V. Sudarsanam, Manish Nivsarkar, Devendra Singh
Publikováno v:
Bioorganic & Medicinal Chemistry. 36:116091
Alzheimer's disease (AD) is a neurodegenerative disease majorly affecting old age populations. Various factors that affect the progression of the disease include, amyloid plaque formation, neurofibrillary tangles, inflammation, oxidative stress, etc.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a455f2ce9dc691ab34bb51dcb7425ca
https://doi.org/10.1016/j.bmc.2021.116091
https://doi.org/10.1016/j.bmc.2021.116091
Publikováno v:
Life Sciences
Aims The severe acute respiratory syndrome coronavirus 2, better known as COVID-19 has become the current health concern to the entire world. Initially appeared in Wuhan, China around December 2019, it had spread to almost 187 countries due to its hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9e853be3151bc2ba67e53bba327963
http://europepmc.org/articles/PMC7194845
http://europepmc.org/articles/PMC7194845
Autor:
Manish Nivsarkar, Sneha R. Sagar, Dhaivat H. Pandya, Nirupa B. Panchal, Devendra Singh, V. Sudarsanam, Rajesh D. Das, Kamala K. Vasu
Publikováno v:
ACS chemical neuroscience. 9(7)
Alzheimer's disease (AD) is associated with multiple neuropathological events including β-site amyloid precursor protein cleaving enzyme-1 (BACE-1) inhibition and neuronal inflammation, ensuing degeneracy, and death to neuronal cells. Targeting such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512f8c8fffc7d104ac12f7d52ab94bdb
https://pubmed.ncbi.nlm.nih.gov/29697965
https://pubmed.ncbi.nlm.nih.gov/29697965
Autor:
Jessica K. Agarwal, Sneha R. Sagar, Kamala K. Vasu, Manish Nivsarkar, Dhaivat H. Pandya, Ranjeet Prasad Dash
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:4428-4433
We report the design, synthesis, biological activity and docking studies of series of novel pyrazolo[3,4-d]pyrimidinones as DPP-IV inhibitors in diabetes. Molecules were synthesized and evaluated for their DPP-IV inhibition activity. Compounds 5e, 5k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67794bfcfa0b4793633bd12bef67cf12
https://doi.org/10.1016/j.bmcl.2015.09.015
https://doi.org/10.1016/j.bmcl.2015.09.015
Autor:
Nirupa B. Panchal, Rajesh D. Das, Manish Nivsarkar, Kamala K. Vasu, Sneha R. Sagar, V. Sudarsanam, Devendra Pratap Singh
Publikováno v:
Bioorganic Chemistry. 89:102992
Alzheimer’s disease (AD) is the most prevalent disease of old age leading to dementia. Complex AD pathogenesis involves multiple factors viz. amyloid plaque formation, neurofibrillary tangles and inflammation. Herein we report of a new series of qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d5dda091542acb5ad245adb6d7490e
https://doi.org/10.1016/j.bioorg.2019.102992
https://doi.org/10.1016/j.bioorg.2019.102992