Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Sneha Pandya"'
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 8, Pp 1755-1759 (2021)
Abstract The objective of this pilot study was to assess a 2‐year change in innate immune burden in 15 progressive multiple sclerosis (MS) patients using PK11195‐PET. Sixteen age‐matched healthy controls (HC) were included for baseline comparis
Externí odkaz:
https://doaj.org/article/f6d5c88a07614bbea10c13a0ed3a23be
Autor:
Sneha Pandya, Pedro D. Maia, Benjamin Freeze, Ricarda A. L. Menke, Kevin Talbot, Martin R. Turner, Ashish Raj
Publikováno v:
NeuroImage, Vol 251, Iss , Pp 118968- (2022)
The neurodegenerative disorder amyotrophic lateral sclerosis (ALS) is characterized by the progressive loss of upper and lower motor neurons, with pathological involvement of cerebral motor and extra-motor areas in a clinicopathological spectrum with
Externí odkaz:
https://doaj.org/article/88ecec0bc2914739a4baba2b3dc133a1
Autor:
Mercy I. Akerele, Sara A. Zein, Sneha Pandya, Anastasia Nikolopoulou, Susan A. Gauthier, Ashish Raj, Claire Henchcliffe, P. David Mozley, Nicolas A. Karakatsanis, Ajay Gupta, John Babich, Sadek A. Nehmeh
Publikováno v:
EJNMMI Physics, Vol 8, Iss 1, Pp 1-17 (2021)
Abstract Introduction Quantitative positron emission tomography (PET) studies of neurodegenerative diseases typically require the measurement of arterial input functions (AIF), an invasive and risky procedure. This study aims to assess the reproducib
Externí odkaz:
https://doaj.org/article/0abed0fc7ec04f42889330944c1c9a00
Autor:
Ceren Tozlu, Keith Jamison, Thanh Nguyen, Nicole Zinger, Ulrike Kaunzner, Sneha Pandya, Yi Wang, Susan Gauthier, Amy Kuceyeski
Publikováno v:
Brain and Behavior, Vol 11, Iss 10, Pp n/a-n/a (2021)
Abstract Background In people with multiple sclerosis (pwMS), lesions with a hyperintense rim (rim+) on Quantitative Susceptibility Mapping (QSM) have been shown to have greater myelin damage compared to rim‐ lesions, but their association with dis
Externí odkaz:
https://doaj.org/article/4c315457e6ee4a13ba3d1c6a8579e208
Autor:
Jana Ivanidze, Myrto Skafida, Sneha Pandya, Dylon Patel, Joseph R. Osborne, Ashish Raj, Ajay Gupta, Claire Henchcliffe, Jonathan P. Dyke
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Parkinson disease (PD) is the second most common neurodegenerative disorder, characterized by loss of nigrostriatal dopaminergic neurons. Impairment of the neurovascular unit (NVU) has been hypothesized to play a critical role in early PD pathophysio
Externí odkaz:
https://doaj.org/article/2dca227d5e784fb38109d6adf21d2dc6
Publikováno v:
NeuroImage: Clinical, Vol 18, Iss , Pp 456-466 (2018)
Multiple genes have been implicated in Parkinson disease pathogenesis, but the relationship between regional expression of these genes and regional dysfunction across the brain is unknown. We address this question by joint analysis of high resolution
Externí odkaz:
https://doaj.org/article/c8db6fa0058e4db2a734d9e8d6cfc5b2
Publikováno v:
Frontiers in Neurology, Vol 8 (2017)
Several neurodegenerative disorders including Alzheimer’s disease (AD), frontotemporal dementia (FTD), Parkinson’s disease (PD), amyotrophic lateral sclerosis, and Huntington’s disease report aggregation and transmission of pathogenic proteins
Externí odkaz:
https://doaj.org/article/e2e76be5d7724caf85a90176fce9ed19
Autor:
Wendy S. Vargas, Elizabeth Monohan, Sneha Pandya, Ashish Raj, Timothy Vartanian, Thanh D. Nguyen, Sandra M. Hurtado Rúa, Susan A. Gauthier
Publikováno v:
NeuroImage: Clinical, Vol 9, Iss C, Pp 369-375 (2015)
Objectives: Investigating the potential of myelin repair strategies in multiple sclerosis (MS) requires an understanding of myelin dynamics during lesion evolution. The objective of this study is to longitudinally measure myelin water fraction (MWF),
Externí odkaz:
https://doaj.org/article/ceaf2356453b4e2596e5d88964429b7a
Autor:
Michael Dayan, Sandra M. Hurtado Rúa, Elizabeth Monohan, Kyoko Fujimoto, Sneha Pandya, Eve M. LoCastro, Tim Vartanian, Thanh D. Nguyen, Ashish Raj, Susan A. Gauthier
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
A novel lesion-mask free method based on a gamma mixture model was applied to myelin water fraction (MWF) maps to estimate the association between cortical thickness and myelin content, and how it differs between relapsing-remitting (RRMS) and second
Externí odkaz:
https://doaj.org/article/736aecfe06fd48148be52cf10269f7d6
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98391 (2014)
The brain's myelin content can be mapped by T2-relaxometry, which resolves multiple differentially relaxing T2 pools from multi-echo MRI. Unfortunately, the conventional fitting procedure is a hard and numerically ill-posed problem. Consequently, the
Externí odkaz:
https://doaj.org/article/75a2b362291240fb8407637b81fa25b0