Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sneha Deodhar"'
Autor:
David P. Cistola, MD, PhD, Vipulkumar Patel, PhD, Sneha Deodhar, MS, Ina Mishra, PhD, Michelle D. Robinson, PhD, Alok K. Dwivedi, Ph.D.
Publikováno v:
American Journal of Preventive Cardiology, Vol 15, Iss , Pp 100576- (2023)
Therapeutic Area: Diabetes Background: Plasma water T2 is an early, global and practical biomarker of cardiometabolic health. It is measured by compact magnetic resonance relaxometry using separated human plasma. A prior goal was to determine whether
Externí odkaz:
https://doaj.org/article/5be4159376ad4a6888d55957772856ce
Publikováno v:
Biomarker Research, Vol 6, Iss 1, Pp 1-12 (2018)
Abstract Background Metabolic syndrome is a cluster of abnormalities that increases the risk for type 2 diabetes and atherosclerosis. Plasma and serum water T2 from benchtop nuclear magnetic resonance relaxometry are early, global and practical bioma
Externí odkaz:
https://doaj.org/article/2c49990ce5d4495da8c05ceb3dbc881f
Autor:
Oludamilola Akinmolayemi, Suzanne Saldanha, Parag H Joshi, Sneha Deodhar, Colby R Ayers, Ian J Neeland, Anand Rohatgi
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257574 (2021)
Metabolic syndrome (MetS) is characterized by adiposity and atherogenic dyslipidemia consisting of elevated triglyceride and decreased high density lipoprotein cholesterol (HDL-C) levels however, cholesterol concentration alone does not reflect HDL f
Externí odkaz:
https://doaj.org/article/80b29ff62df94e249b987cb2848c3a55
Autor:
Mark P. Metzinger, Suzanne Saldanha, Jaskeerat Gulati, Kershaw V. Patel, Ayea El‐Ghazali, Sneha Deodhar, Parag H. Joshi, Colby Ayers, Anand Rohatgi
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 24 (2020)
Background Anacetrapib is the only cholesteryl ester transfer protein inhibitor proven to reduce coronary heart disease (CHD). However, its effects on reverse cholesterol transport have not been fully elucidated. Macrophage cholesterol efflux (CEC),
Externí odkaz:
https://doaj.org/article/2aa748d15d9d4a0e87bc864dcb3f2b51
Autor:
Michelle D. Robinson, Ina Mishra, Sneha Deodhar, Vipulkumar Patel, Katrina V. Gordon, Raul Vintimilla, Kim Brown, Leigh Johnson, Sid O’Bryant, David P. Cistola
Publikováno v:
Journal of Translational Medicine, Vol 15, Iss 1, Pp 1-19 (2017)
Abstract Background Metabolic syndrome (MetS) is a highly prevalent condition that identifies individuals at risk for type 2 diabetes mellitus and atherosclerotic cardiovascular disease. Prevention of these diseases relies on early detection and inte
Externí odkaz:
https://doaj.org/article/dd024087cf344d8d99f38aef8f44c1a7
Autor:
Mark Izbrand, Sneha Deodhar, Mandana Pahlavani, Suzanne Saldanha, Brooke Smyth, Anand Rohatgi, Anamika Gangwar, Ayea El-Ghazali
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: Cholesterol efflux capacity (CEC), the ability of extracellular acceptors to pick-up cholesterol from macrophages, is a clinically relevant cardiovascular biomarker. CEC is inversely associated with incident atherosclerotic cardiovascular
Autor:
Mandana Pahlavani, Suzanne Saldanha, Sneha Deodhar, Lydia Thenayan, Robert Haley, Elaine Wu, Anamika Gangwar, Anand Rohatgi
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Reverse cholesterol transport is a main anti-atherosclerotic function of high-density lipoprotein (HDL), and cholesterol efflux capacity (CEC) is a key first step of this function. Inflammation and oxidation are metabolically linked to cholesterol tr
Autor:
Anamika Gangwar, Suzanne Saldanha, Sneha Deodhar, Elaine Wu, MinJae Lee, Mandana Pahlavani, Lydia Thenayan, Jeremy D Furtado, Frank M Sacks, Anand Rohatgi
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Cholesterol efflux (CE) is a major athero-protective function of high density lipoproteins (HDL). HDL is a heterogeneous mixture of lipoproteins that contain apoA1, the prime protein of HDL, and may contain one or more of >200 other proteins. These o
Publikováno v:
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy. 11:807-818
Background The ability to use frozen biobanked samples from cohort studies and clinical trials is critically important for biomarker discovery and validation. Here we investigated whether plasma and serum water transverse relaxation times (T2) from f
Publikováno v:
Biomarker Research, Vol 6, Iss 1, Pp 1-12 (2018)
Background Metabolic syndrome is a cluster of abnormalities that increases the risk for type 2 diabetes and atherosclerosis. Plasma and serum water T2 from benchtop nuclear magnetic resonance relaxometry are early, global and practical biomarkers for