Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sneha Bairy"'
Autor:
Vikrant Kumar, Puneeth Kumar Chunchagatta Lakshman, Thazhe Kootteri Prasad, Kavyashree Manjunath, Sneha Bairy, Akshaya S. Vasu, B. Ganavi, Subbarao Jasti, Neelagandan Kamariah
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23864- (2024)
Target-based discovery of first-in-class therapeutics demands an in-depth understanding of the molecular mechanisms underlying human diseases. Precise measurements of cellular and biochemical activities are critical to gain mechanistic knowledge of b
Externí odkaz:
https://doaj.org/article/db664869fa4c445ba01299e12ca67ed2
Autor:
Venkadeshwari Varadharajan, Sumukh Mysore, Ram Rajasekharan, Chetan Chandola, Muniasamy Neerathilingam, Sneha Bairy
The antibiotic stress on bacteria leads to initiation of adaptive mechanisms, including exploiting the available opportunity, if any, for cell survival. In order to use the opportunity for survival while under threat, the microbe undergoes various me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09dca883f5a5d2d09ff18b3b48c102e3
https://doi.org/10.1101/2020.05.27.114090
https://doi.org/10.1101/2020.05.27.114090
Autor:
Jyoti Sharma, Sneha Bairy, Chetan Chandola, Alisha Parveen, Phulwanti Kumari Sharma, Vibha Kaushik, Akhil Agarwal, Pankaj Goyal, Abhishek Kumar, Narendra Kumar, Akhilesh Pandey, Muniasamy Neerathilingam
Severe acute respiratory syndrome novel coronavirus 2 (SARS-CoV-2) has caused the global pandemic as COVID-19, which is the most notorious global public health crisis in the last 100 years. SARS-CoV-2 is composed of four structural proteins and sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb30bff673567a79dfd3e05f57a9518b
https://doi.org/10.20944/preprints202005.0413.v1
https://doi.org/10.20944/preprints202005.0413.v1
Autor:
Vikrant Kumar, Bryn Hardwick, Saranya Giridharan, Sneha Sudhakar, Markus Muellner, Manjunath A. Hurakadli, Ashok R. Venkitaraman, Gayathri Sadasivam, T.K. Prasad, Neelagandan Kamariah, Grahame J. McKenzie, Alex T. Crooks, Subashini Mathivanan, Paul M. Watt, Miguel Coelho, Sneha Bairy, Nadia Milech, Chandan Mithra, Christopher J. Torrance, Amy Emery, Kavitha Bharatham
Publikováno v:
Cell Chemical Biology
Summary Genetic screening technologies to identify and validate macromolecular interactions (MMIs) essential for complex pathways remain an important unmet need for systems biology and therapeutics development. Here, we use a library of peptides from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82261f81e78bea18e12f385b6c100941
https://doi.org/10.1016/j.chembiol.2021.05.009
https://doi.org/10.1016/j.chembiol.2021.05.009
Autor:
Sneha Bairy, Chung F. Wong
Publikováno v:
Current Pharmaceutical Design. 19:4739-4754
This article reviews some of our experiences on applying computational techniques to aid the design of drugs targeting protein kinases and phosphatases. It is not a comprehensive review. Rather, it focuses on several less explored approaches or ideas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e73ccd3911592f73328526fa3845e03
https://doi.org/10.2174/1381612811319260006
https://doi.org/10.2174/1381612811319260006
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 2, p e0150153 (2016)
PLoS ONE, Vol 11, Iss 2, p e0150153 (2016)
Intrinsically disordered proteins (IDPs) play a major role in various cellular functions ranging from transcription to cell migration. Mutations/modifications in such IDPs are shown to be associated with various diseases. Current strategies to study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f65e33e836af1cab37fde3c6ffd805
https://doi.org/10.1371/journal.pone.0150153
https://doi.org/10.1371/journal.pone.0150153
Autor:
Chung F. Wong, Sneha Bairy
Publikováno v:
Proteins. 79(8)
We used three models of the epidermal growth factor receptor (EGFR) signaling pathway mimicking three different cell lines to study the effects of kinetics of drug binding on influencing molecular signaling in the pathways. With no incubation of drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51bcf73d687a1a4dbeba65db4197ffd8
https://pubmed.ncbi.nlm.nih.gov/21638335
https://pubmed.ncbi.nlm.nih.gov/21638335