Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Snahlata, Singh"'
Autor:
Sushil Kumar, Ajeya Nandi, Snahlata Singh, Rohan Regulapati, Ning Li, John W. Tobias, Christian W. Siebel, Mario Andres Blanco, Andres J. Klein-Szanto, Christopher Lengner, Alana L. Welm, Yibin Kang, Rumela Chakrabarti
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Although activated Notch receptors have been associated with chemoresistance in cancer, the role of specific Notch ligands remain elusive. Here, the authors show that in breast cells the Notch ligand DLL1 is expressed in cells with a cancer stem cell
Externí odkaz:
https://doaj.org/article/a82e2a88c87b4da18c5103c84eb99f0b
Autor:
Sushil Kumar, Ajeya Nandi, Snahlata Singh, Rohan Regulapati, Ning Li, John W. Tobias, Christian W. Siebel, Mario Andres Blanco, Andres J. Klein-Szanto, Christopher Lengner, Alana L. Welm, Yibin Kang, Rumela Chakrabarti
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/515147b47c8045f7a83bb33af1989d17
Autor:
Dipti Athavale, Surbhi Chouhan, Vimal Pandey, Shyamananda Singh Mayengbam, Snahlata Singh, Manoj Kumar Bhat
Publikováno v:
Cancer & Metabolism, Vol 6, Iss 1, Pp 1-16 (2018)
Abstract Background PCSK9 regulates low-density lipoprotein cholesterol (LDLc) level and has been implicated in hypercholesterolemia. Aberrant plasma lipid profile is often associated with various cancers. Clinically, the relationship between altered
Externí odkaz:
https://doaj.org/article/14605acedb8141b393b5e4e26598e329
Autor:
Parmanand Malvi, Balkrishna Chaube, Shivendra Vikram Singh, Naoshad Mohammad, Maleppillil Vavachan Vijayakumar, Snahlata Singh, Surbhi Chouhan, Manoj Kumar Bhat
Publikováno v:
Cancer & Metabolism, Vol 6, Iss 1, Pp 1-14 (2018)
Abstract Background Obesity is associated with increased risk, poor prognosis and outcome of therapy, in various cancers. Obesity-associated factors or adipokines, especially leptin and resistin, are purported to promote growth, survival, proliferati
Externí odkaz:
https://doaj.org/article/74b9d291729a4a0b805903865eb5c703
Autor:
Gatha Thacker, Samantha Henry, Ajeya Nandi, Rahul Debnath, Snahlata Singh, Anupma Nayak, Barbara Susnik, Melinda M Boone, Qing Zhang, Susan B Kesmodel, Sanjeev Gumber, Gokul M Das, Taku Kambayashi, Camila O. Dos Santos, Rumela Chakrabarti
Publikováno v:
Science Translational Medicine. 15
Natural killer (NK) cells are cytotoxic lymphocytes that accumulate within the tumor microenvironment and are generally considered to be antitumorigenic. Using single-cell RNA sequencing and functional analysis of multiple triple-negative breast canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9dc6ce2faa5020a11f53ad49231b323d
https://doi.org/10.1126/scitranslmed.abl4414
https://doi.org/10.1126/scitranslmed.abl4414
Autor:
John W. Tobias, Mario Andres Blanco, Snahlata Singh, Sushil Kumar, Alana L. Welm, Christopher J. Lengner, Rumela Chakrabarti, Yibin Kang, Christian W. Siebel, Andres J. Klein-Szanto, Ajeya Nandi, Rohan Regulapati, Ning Li
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Development of chemoresistance in breast cancer patients greatly increases mortality. Thus, understanding mechanisms underlying breast cancer resistance to chemotherapy is of paramount importance to overcome this clinical challenge. Although activate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7a71feec96e8378f6c5d3d7d7162d3d
https://doaj.org/article/a82e2a88c87b4da18c5103c84eb99f0b
https://doaj.org/article/a82e2a88c87b4da18c5103c84eb99f0b
Autor:
Hemma Murali, Ajeya Nandi, Serge Y. Fuchs, Ratnesh Kumar Srivastava, Sabrina Kim, M. Raza Zaidi, Snahlata Singh, Mario Andres Blanco, Sushil Kumar, Rizwan Saffie, Gatha Thacker, Luca Busino, Mary Baldeon, Rumela Chakrabarti, Satrajit Sinha, John W. Tobias
Publikováno v:
Nat Cell Biol
Triple-negative breast cancer (TNBC) is characterized by a high degree of immune infiltrate in the tumour microenvironment, which may influence the fate of TNBC cells. We reveal that loss of the tumour suppressive transcription factor Elf5 in TNBC ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::757521dabbdecdc7ed63bf4e14d709ad
https://doi.org/10.1038/s41556-020-0495-y
https://doi.org/10.1038/s41556-020-0495-y
Autor:
Snahlata Singh, Emily Elenio, Rose-Anne Romano, Nicolae Adrian Leu, Andrew E. Vaughan, Rumela Chakrabarti, Jennifer deRiso, Kameswaran Surendran
Publikováno v:
FEBS Letters. 593:1030-1039
Elf5 is a transcription factor known to regulate critical developmental processes and has been shown to act as a tumour suppressor in multiple cancers. Elf5 knockout mice are embryonically lethal, limiting in vivo studies pertaining to its function.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f474b399ad44b3ba5d2a2232dc991001
https://doi.org/10.1002/1873-3468.13390
https://doi.org/10.1002/1873-3468.13390
Autor:
Dipti Athavale, Pranay Ramteke, Bipin G. Nair, Snahlata Singh, Muralidharan Vanuopadath, Sudarslal Sadasivan Nair, Manoj Kumar Bhat, Surbhi Chouhan
Publikováno v:
Journal of Biosciences. 45
Altered glucose uptake and metabolism is the key characteristic of cancer cells including hepatocellular carcinoma (HCC). However, role of glucose availability in chemotherapeutic outcome of HCC is unclear. The present study investigates the effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b47fbe3e6aae9cd2bf1b398717615f
https://doi.org/10.1007/s12038-020-00065-y
https://doi.org/10.1007/s12038-020-00065-y
Autor:
Shivendra V. Singh, Snahlata Singh, Balkrishna Chaube, Surbhi Chouhan, Naoshad Mohammad, Maleppillil Vavachan Vijayakumar, Manoj Kumar Bhat, Parmanand Malvi
Publikováno v:
Cancer & Metabolism, Vol 6, Iss 1, Pp 1-14 (2018)
Cancer & Metabolism
Cancer & Metabolism
Background Obesity is associated with increased risk, poor prognosis and outcome of therapy, in various cancers. Obesity-associated factors or adipokines, especially leptin and resistin, are purported to promote growth, survival, proliferation, and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::608c0e636293628a1981086b6e912c8a
http://link.springer.com/article/10.1186/s40170-018-0176-5
http://link.springer.com/article/10.1186/s40170-018-0176-5