A partial loss-of-function variant in STAT6 protects against type 2 asthma

Autor: Kristjansdottir, Katla, Norddahl, Gudmundur L., Ivarsdottir, Erna V., Halldorsson, Gisli H., Einarsson, Gudmundur, Bjarnadottir, Kristbjorg, Rutsdottir, Gudrun, Arnthorsson, Asgeir O., Erikstrup, Christian, Gudmundsdottir, Steinunn, Gunnarsdottir, Kristbjorg, Gunnbjornsdottir, Maria I., Halldorsson, Bjarni V., Holm, Hilma, Ludviksdottir, Dora, Ludviksson, Bjorn R., Brunak, Søren, Bruun, Mie Topholm, Mikkelsen, Christina, Mikkelsen, Susan, Jensen, Bitten Aagaard, Sørensen, Erik, Thomsen, Simon Francis, Ullum, Henrik, Olafsson, Isleifur, Onundarson, Pall T., Ostrowski, Sisse Rye, Saevarsdottir, Saedis, Sigurdardottir, Olof, Sigurgeirsson, Bardur, Snaebjarnarson, Audunn S., Sveinbjornsson, Gardar, Thorlacius, Gudny E., Thorleifsson, Gudmar, Tragante, Vinicius, Vidarsson, Brynjar, Porsbjerg, Celeste, Bjornsdottir, Unnur S., Sulem, Patrick, Gudbjartsson, Daniel F., Melsted, Pall, Pedersen, Ole Bv., Jonsdottir, Ingileif, Olafsdottir, Thorunn A., Stefansson, Kari

Publikováno v: In The Journal of Allergy and Clinical Immunology October 2024

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Sequence variants associated with BMI affect disease risk through BMI itself.

Autor: Einarsson, Gudmundur, Thorleifsson, Gudmar, Steinthorsdottir, Valgerdur, Zink, Florian, Helgason, Hannes, Olafsdottir, Thorhildur, Rognvaldsson, Solvi, Tragante, Vinicius, Ulfarsson, Magnus O., Sveinbjornsson, Gardar, Snaebjarnarson, Audunn S., Einarsson, Hafsteinn, Aegisdottir, Hildur M., Jonsdottir, Gudrun A., Helgadottir, Anna, Gretarsdottir, Solveig, Styrkarsdottir, Unnur, Arnason, Hannes K., Bjarnason, Ragnar, Sigurdsson, Emil

Publikováno v: Nature Communications; 11/12/2024, Vol. 15 Issue 1, p1-9, 9p

Rapid Polynomial Approximation on Stein Manifolds

Autor: Snaebjarnarson, Audunn Skuta

In this paper we generalize to a certain class of Stein manifolds the Bernstein-Walsh-Siciak theorem which describes the equivalence between possible holomorphic continuation of a function $f$ defined on a compact set $K$ in $\mathbb{C}^N$ to the rap

Externí odkaz: http://arxiv.org/abs/1612.06173

Cholesterol not particle concentration mediates the atherogenic risk conferred by apolipoprotein B particles:A Mendelian randomization analysis

Autor: Helgadottir, Anna, Thorleifsson, Gudmar, Snaebjarnarson, Audunn, Stefansdottir, Lilja, Sveinbjornsson, Gardar, Tragante, Vinicius, Björnsson, Eyþór, Steinthorsdottir, Valgerdur, Gretarsdottir, Solveig, Helgason, Hannes, Saemundsdottir, Jona, Olafsson, Isleifur, Thune, Jens Jakob, Axelsson Raja, Anna, Ghouse, Jonas, Olesen, Morten Salling, Christensen, Alex, Jacobsen, Rikke Louise, Dowsett, Joseph, Bruun, Mie Topholm, Nielsen, Kaspar, Knowlton, Kirk, Nadauld, Lincoln, Benediktsson, Rafn, Erikstrup, Christian, Pedersen, Ole B., Banasik, Karina, Brunak, Søren, Bundgaard, Henning, Ostrowski, Sisse R., Sulem, Patrick, Arnar, David O., Thorgeirsson, Gudmundur, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Stefansson, Kari, Holm, Hilma, Nyegaard, Mette

Publikováno v: Helgadottir, A, Thorleifsson, G, Snaebjarnarson, A, Stefansdottir, L, Sveinbjornsson, G, Tragante, V, Björnsson, E, Steinthorsdottir, V, Gretarsdottir, S, Helgason, H, Saemundsdottir, J, Olafsson, I, Thune, J J, Axelsson Raja, A, Ghouse, J, Olesen, M S, Christensen, A, Jacobsen, R L, Dowsett, J, Bruun, M T, Nielsen, K, Knowlton, K, Nadauld, L, Benediktsson, R, Erikstrup, C, Pedersen, O B, Banasik, K, Brunak, S, Bundgaard, H, Ostrowski, S R, Sulem, P, Arnar, D O, Thorgeirsson, G, Thorsteinsdottir, U, Gudbjartsson, D F, Stefansson, K, Holm, H & DBDS Genomic Consortium 2022, ' Cholesterol not particle concentration mediates the atherogenic risk conferred by apolipoprotein B particles : A Mendelian randomization analysis ', European Journal of Preventive Cardiology, vol. 29, no. 18, pp. 2374-2385 . https://doi.org/10.1093/eurjpc/zwac219
Helgadottir, A, Thorleifsson, G, Snaebjarnarson, A, Stefansdottir, L, Sveinbjornsson, G, Tragante, V, Björnsson, E, Steinthorsdottir, V, Gretarsdottir, S, Helgason, H, Saemundsdottir, J, Olafsson, I, Thune, J J, Axelsson Raja, A, Ghouse, J, Olesen, M S, Christensen, A, Jacobsen, R L, Dowsett, J, Bruun, M T, Nielsen, K, Knowlton, K, Nadauld, L, Benediktsson, R, Erikstrup, C, Pedersen, O B, Banasik, K, Brunak, S, DBDS Genomic Consortium, Bundgaard, H, Ostrowski, S R, Sulem, P, Arnar, D O, Thorgeirsson, G, Thorsteinsdottir, U, Gudbjartsson, D F, Stefansson, K, Holm, H & Nyegaard, M 2022, ' Cholesterol not particle concentration mediates the atherogenic risk conferred by apolipoprotein B particles-A Mendelian randomization analysis ', European Journal of Preventive Cardiology, vol. 29, no. 18, zwac219, pp. 2374-2385 . https://doi.org/10.1093/eurjpc/zwac219
Helgadottir, A, Thorleifsson, G, Snaebjarnarson, A, Stefansdottir, L, Sveinbjornsson, G, Tragante, V, Björnsson, E, Steinthorsdottir, V, Gretarsdottir, S, Helgason, H, Saemundsdottir, J, Olafsson, I, Thune, J J, Axelsson Raja, A, Ghouse, J, Olesen, M S, Christensen, A, Jacobsen, R L, Dowsett, J, Bruun, M T, Nielsen, K, Knowlton, K, Nadauld, L, Benediktsson, R, Erikstrup, C, Pedersen, O B, Banasik, K, Brunak, S, Bundgaard, H, Ostrowski, S R, Sulem, P, Arnar, D O, Thorgeirsson, G, Thorsteinsdottir, U, Gudbjartsson, D F, Stefansson, K, Holm, H & DBDS Genomic Consortium 2022, ' Cholesterol not particle concentration mediates the atherogenic risk conferred by apolipoprotein B particles-A Mendelian randomization analysis ', European Journal of Preventive Cardiology, vol. 29, no. 18, pp. 2374–2385 . https://doi.org/10.1093/eurjpc/zwac219

Background and aims:The causal contribution of apolipoprotein B (apoB) particles to coronary artery disease (CAD) is established. We examined whether this atherogenic contribution is better reflected by non-high-density lipoprotein cholesterol (non-H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c5f7c1eecea2efbebbb8764d66f63fd
https://pure.au.dk/portal/da/publications/cholesterol-not-particle-concentration-mediates-the-atherogenic-risk-conferred-by-apolipoprotein-b-particles(6ba7ddb1-b4a5-423c-9f98-107bd8082294).html