Reversible Thrombocytopenia of Functional Platelets after Nose-Horned Viper Envenomation Is Induced by a Snaclec.

Autor: Dobaja Borak M; Centre for Clinical Toxicology and Pharmacology, University Medical Centre Ljubljana, Ljubljana, Slovenia.; Doctoral School, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia., Leonardi A; Department of Molecular and Biomedical Sciences, Jožef Stefan Institute, Ljubljana, Slovenia., Požek K; Doctoral School, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.; Department of Molecular and Biomedical Sciences, Jožef Stefan Institute, Ljubljana, Slovenia., Reberšek K; Department of Haematology, University Medical Centre Ljubljana, Ljubljana, Slovenia., Podgornik H; Department of Haematology, University Medical Centre Ljubljana, Ljubljana, Slovenia.; Department of Clinical Biochemistry, Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia., Pirnat A; Division of Paediatrics, University Medical Centre Ljubljana, Ljubljana, Slovenia., Trampuš Bakija A; Division of Paediatrics, University Medical Centre Ljubljana, Ljubljana, Slovenia., Kranjc Brezar S; Department of Experimental Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia., Trobec T; Institute of Preclinical Sciences, Veterinary Faculty, University of Ljubljana, Ljubljana, Slovenia., Žužek MC; Institute of Preclinical Sciences, Veterinary Faculty, University of Ljubljana, Ljubljana, Slovenia., Frangež R; Institute of Preclinical Sciences, Veterinary Faculty, University of Ljubljana, Ljubljana, Slovenia., Brvar M; Centre for Clinical Toxicology and Pharmacology, University Medical Centre Ljubljana, Ljubljana, Slovenia.; Center for Clinical Physiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia., Križaj I; Department of Molecular and Biomedical Sciences, Jožef Stefan Institute, Ljubljana, Slovenia.

Publikováno v: Thrombosis and haemostasis [Thromb Haemost] 2024 Sep 23. Date of Electronic Publication: 2024 Sep 23.

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Anticoagulation factor I, a snaclec (snake C-type lectin) from Agkistrodon acutus venom binds to FIX as well as FX: Ca2+ induced binding data

Autor: Zhang, Yan, Xu, Xiaolong, Shen, Dengke, Song, Jiajia, Guo, Mingchun, Yan, Xincheng

Publikováno v: In Toxicon 1 June 2012 59(7-8):718-723

Computational and in vitro analyses to identify the anticoagulant regions of Echicetin, a snake venom anticoagulant C-type lectin (snaclec): possibility to develop anticoagulant peptide therapeutics?

Autor: Upasana Puzari, Mahasweta Goswami, Komal Rani, Aparup Patra, Ashis K. Mukherjee

Snake venom C-type lectins (Snaclecs) display anticoagulant and platelet-modulating activities; however, their interaction with the critical components of blood coagulation factors was unknown. Computational analysis revealed that Echicetin (Snaclec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97fcd528a5a280ef9132ae4ee571dd05

Anticoagulation factor I, a snaclec (snake C-type lectin) from Agkistrodon acutus venom binds to FIX as well as FX: Ca²⁺ induced binding data

Autor: Zhang, Yan¹, Xu, Xiaolong xuxl@ustc.edu.cn, Shen, Dengke¹, Song, Jiajia¹, Guo, Mingchun¹, Yan, Xincheng¹

Publikováno v: Toxicon. Jun2012, Vol. 59 Issue 7/8, p718-723. 6p.