Cerebrovascular and Alzheimer's disease biomarkers in dementia with Lewy bodies and other dementias.

Autor: Rennie A; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 171 77 Stockholm, Sweden., Ekman U; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 171 77 Stockholm, Sweden.; Medical Unit, Allied Health Professionals Women´s Health, Karolinska University Hospital, 171 76 Stockholm, Sweden., Shams S; Department of Radiology, Karolinska University Hospital, 171 76 Stockholm, Sweden.; Department of Clinical Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden.; Department of Radiology, Stanford University, Stanford, 94305-5105 CA, USA., Rydén L; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, 431 41 Mölndal, Sweden.; Centre for Ageing and Health (AgeCap), University of Gothenburg, 413 46 Gothenburg, Sweden., Samuelsson J; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, 431 41 Mölndal, Sweden.; Centre for Ageing and Health (AgeCap), University of Gothenburg, 413 46 Gothenburg, Sweden., Zettergren A; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, 431 41 Mölndal, Sweden.; Centre for Ageing and Health (AgeCap), University of Gothenburg, 413 46 Gothenburg, Sweden., Kern S; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, 431 41 Mölndal, Sweden.; Centre for Ageing and Health (AgeCap), University of Gothenburg, 413 46 Gothenburg, Sweden.; Psychiatry, Cognition and Old Age Psychiatry Clinic, Region Västra Götaland, Sahlgrenska University Hospital, 431 41 Gothenburg, Sweden., Oppedal K; Center for Age-Related Medicine, Stavanger University Hospital, 4011 Stavanger, Norway.; Stavanger Medical Imaging Laboratory (SMIL), Department of Radiology, Stavanger University Hospital, 4016 Stavanger, Norway.; The Norwegian Centre for Movement Disorders, Stavanger University Hospital, 4011 Stavanger, Norway., Blanc F; Day Hospital of Geriatrics, Memory Resource and Research Centre (CM2R) of Strasbourg, Department of Geriatrics, Hopitaux Universitaires de Strasbourg, 67098 Strasbourg, France.; ICube Laboratory and Federation de Medecine Translationnelle de Strasbourg (FMTS), University of Strasbourg and French National Centre for Scientific Research (CNRS), Team Imagerie Multimodale Integrative en Sante (IMIS)/ICONE, 67000 Strasbourg, France., Hort J; Memory Clinic, Department of Neurology, Second Faculty of Medicine, Charles University and Motol University Hospital, 150 06 Prague, Czech Republic., Garcia-Ptacek S; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 171 77 Stockholm, Sweden.; Aging and Inflammation Theme, Karolinska University Hospital, 171 76 Stockholm, Sweden., Antonini A; Parkinson and Movement Disorders Unit, Study Center on Neurodegeneration (CESNE), 35129 Padova, Italy., Lemstra AW; Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location Vumc, 1081 HV Amsterdam, The Netherlands.; Amsterdam Neuroscience, Neurodegeneration, Vrije Universiteit Amsterdam, Amsterdam UMC location Vumc, 1081 HV Amsterdam, The Netherlands., Padovani A; Neurology Unit, Department of Clinical and Experimental Sciences (DSCS), University of Brescia, 25123 Brescia, Italy., Kramberger MG; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 171 77 Stockholm, Sweden.; Department of Neurology, University Medical Center, 1000 Ljubljana, Slovenia.; Medical Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia., Rektorová I; Applied Neuroscience Research Group, CEITEC, Masaryk University, 625 00 Brno, Czech Republic., Walker Z; Division of Psychiatry, University College London, W1T 7NF London, UK.; St Margaret's Hospital, Essex Partnership University NHS Foundation Trust, CM16 6TN Essex, UK., Snædal J; Memory Clinic, Landspitali, 105 Reykjavik, Iceland., Pardini M; Department of Neurology, IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, 16132 Genoa, Italy., Taylor JP; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, NE1 7RU Newcastle upon Tyne, UK., Bonanni L; Department of Medicine, Aging Sciences University G. d'Annunzio of Chieti-Pescara Chieti, 66100 Chieti, Italy., Granberg T; Department of Radiology, Karolinska University Hospital, 171 76 Stockholm, Sweden.; Department of Clinical Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden., Aarsland D; Center for Age-Related Medicine, Stavanger University Hospital, 4011 Stavanger, Norway.; Department of Old Age Psychiatry, Institute of Psychiatry, Psychology & Neuroscience (IoPPN), King's College London, SE5 8AF London, UK., Skoog I; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, 431 41 Mölndal, Sweden.; Centre for Ageing and Health (AgeCap), University of Gothenburg, 413 46 Gothenburg, Sweden.; Psychiatry, Cognition and Old Age Psychiatry Clinic, Region Västra Götaland, Sahlgrenska University Hospital, 431 41 Gothenburg, Sweden., Wahlund LO; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 171 77 Stockholm, Sweden., Kivipelto M; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 171 77 Stockholm, Sweden.; Aging and Inflammation Theme, Karolinska University Hospital, 171 76 Stockholm, Sweden.; Ageing Epidemiology Research Unit, School of Public Health, Imperial College London, SW7 2AZ London, UK.; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, 70211 Kuopio, Finland., Westman E; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 171 77 Stockholm, Sweden.; Department of Neuroimaging, Centre for Neuroimaging Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College London, SE5 8AF London, UK., Ferreira D; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, 171 77 Stockholm, Sweden.; Facultad de Ciencias de la Salud, Universidad Fernando Pessoa Canarias, 35016 Las Palmas, España.

Publikováno v: Brain communications [Brain Commun] 2024 Aug 28; Vol. 6 (5), pp. fcae290. Date of Electronic Publication: 2024 Aug 28 (Print Publication: 2024).

Ceruloplasmin and iron in Alzheimer’s disease and Parkinson’s disease: a synopsis of recent studies

Autor: Kristinsson J, Snaedal J, Tórsdóttir G, Jóhannesson T

Publikováno v: Neuropsychiatric Disease and Treatment, Vol 2012, Iss default, Pp 515-521 (2012)

Jakob Kristinsson,1 Jón Snaedal,2 Gudlaug Tórsdóttir,1,2 Torkell Jóhannesson11Department of Pharmacology and Toxicology, University of Iceland, Reykjavik, Iceland; 2Department of Geriatrics, Landspitali University Hospital, Reykjavik, IcelandAbst

Externí odkaz: https://doaj.org/article/dd13995211df446cbde251f2cf38d684

Sex differences in brain atrophy in dementia with Lewy bodies.

Autor: Oltra J; University of Barcelona., Habich A; Karolinska Insitutet., Schwarz CG; Mayo Clinic and Foundation., Nedelska Z; Charles University., Przybelski SA; Mayo Clinic and Foundation., Inguanzo A; Karolinska Insitutet., Diaz-Galvan P; Mayo Clinic and Foundation., Lowe VJ; Mayo Clinic and Foundation., Oppedal K; University of Stavanger., Blanc F; University Hospital of Strasbourg., Lemstra AW; VU University., Hort J; Charles University., Padovani A; University of Brescia., Rektorova I; Masaryk University., Bonanni L; University of Chieti - Pescara., Massa F; University of Genoa., Kramberge MG; Ljubljana University., Taylor JP; Newcastle University., Snædal J; Landspitali University Hospital., Walker Z; University College London., Antonini A; University of Padua., Segura B; University of Barcelona., Junque C; University of Barcelona., Westman E; Karolinska Institutet., Boeve BF; Mayo Clinic and Foundation., Aarsland D; King's College London., Kantarci K; Mayo Clinic and Foundation., Ferreira D; Karolisnka Institutet.

Publikováno v: Research square [Res Sq] 2023 Jan 27. Date of Electronic Publication: 2023 Jan 27.

Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease.

Autor: Wightman DP; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU Amsterdam, Amsterdam, the Netherlands., Jansen IE; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU Amsterdam, Amsterdam, the Netherlands., Savage JE; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU Amsterdam, Amsterdam, the Netherlands., Shadrin AA; NORMENT Centre, University of Oslo, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Bahrami S; NORMENT Centre, University of Oslo, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Holland D; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA., Rongve A; Department of Research and Innovation, Helse Fonna, Haugesund Hospital, Haugesund, Norway.; The University of Bergen, Institute of Clinical Medicine (K1), Bergen, Norway., Børte S; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Research and Communication Unit for Musculoskeletal Health (FORMI), Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway., Winsvold BS; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.; Department of Neurology, Oslo University Hospital, Oslo, Norway., Drange OK; Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Division of Mental Health Care, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Martinsen AE; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway., Skogholt AH; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Willer C; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA., Bråthen G; Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Neurology and Clinical Neurophysiology, University Hospital of Trondheim, Trondheim, Norway.; Department of Geriatrics, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway., Bosnes I; Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Psychiatry, Hospital Namsos, Nord-Trøndelag Health Trust, Namsos, Norway., Nielsen JB; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Fritsche LG; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA., Thomas LF; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Pedersen LM; Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway., Gabrielsen ME; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway., Johnsen MB; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Research and Communication Unit for Musculoskeletal Health (FORMI), Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway., Meisingset TW; Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Neurology and Clinical Neurophysiology, University Hospital of Trondheim, Trondheim, Norway., Zhou W; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Proitsi P; Institute of Psychiatry Psychology and Neurosciences, King's College London, London, UK., Hodges A; Institute of Psychiatry Psychology and Neurosciences, King's College London, London, UK., Dobson R; Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.; NIHR Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK.; Health Data Research UK London, University College London, London, UK.; Institute of Health Informatics, University College London, London, UK.; NIHR Biomedical Research Centre at University College London Hospitals NHS Foundation Trust, London, UK., Velayudhan L; Institute of Psychiatry Psychology and Neurosciences, King's College London, London, UK., Heilbron K; 23andMe Inc., Sunnyvale, CA, USA., Auton A; 23andMe Inc., Sunnyvale, CA, USA., Sealock JM; Division of Genetic Medicine, Department of Medicine Vanderbilt University Medical Center Nashville, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Davis LK; Division of Genetic Medicine, Department of Medicine Vanderbilt University Medical Center Nashville, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Reynolds CA; Department of Psychology, University of California-Riverside, Riverside, CA, USA., Karlsson IK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Institute of Gerontology and Aging Research Network - Jönköping (ARN-J), School of Health and Welfare, Jönköping University, Jönköping, Sweden., Magnusson S; deCODE Genetics/Amgen, Reykjavik, Iceland., Stefansson H; deCODE Genetics/Amgen, Reykjavik, Iceland., Thordardottir S; Department of Geriatric Medicine, Landspitali University Hospital, Reykjavik, Iceland., Jonsson PV; Department of Geriatric Medicine, Landspitali University Hospital, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Snaedal J; Department of Geriatric Medicine, Landspitali University Hospital, Reykjavik, Iceland., Zettergren A; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, Centre for Ageing and Health (AGECAP) at the University of Gothenburg, Gothenburg, Sweden., Skoog I; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, Centre for Ageing and Health (AGECAP) at the University of Gothenburg, Gothenburg, Sweden.; Region Västra Götaland, Sahlgrenska University Hospital, Psychiatry, Cognition and Old Age Psychiatry Clinic, Gothenburg, Sweden., Kern S; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, Centre for Ageing and Health (AGECAP) at the University of Gothenburg, Gothenburg, Sweden.; Region Västra Götaland, Sahlgrenska University Hospital, Psychiatry, Cognition and Old Age Psychiatry Clinic, Gothenburg, Sweden., Waern M; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, Centre for Ageing and Health (AGECAP) at the University of Gothenburg, Gothenburg, Sweden.; Region Västra Götaland, Sahlgrenska University Hospital, Psychosis Clinic, Gothenburg, Sweden., Zetterberg H; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; UK Dementia Research Institute at UCL, London, UK.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden., Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden., Stordal E; Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Psychiatry, Hospital Namsos, Nord-Trøndelag Health Trust, Namsos, Norway., Hveem K; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Center, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway., Zwart JA; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway., Athanasiu L; NORMENT Centre, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Selnes P; Department of Neurology, Akershus University Hospital, Lørenskog, Norway., Saltvedt I; Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Geriatrics, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway., Sando SB; Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Neurology and Clinical Neurophysiology, University Hospital of Trondheim, Trondheim, Norway., Ulstein I; Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway., Djurovic S; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway.; NORMENT, Department of Clinical Science, University of Bergen, Bergen, Norway., Fladby T; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Neurology, Akershus University Hospital, Lørenskog, Norway., Aarsland D; Institute of Psychiatry Psychology and Neurosciences, King's College London, London, UK.; Centre of Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway., Selbæk G; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway.; Norwegian National Advisory Unit on Ageing and Health, Vestfold Hospital Trust, Tønsberg, Norway., Ripke S; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Psychiatry and Psychotherapy, Charité-Universitätsmedizin, Berlin, Germany., Stefansson K; deCODE Genetics/Amgen, Reykjavik, Iceland., Andreassen OA; NORMENT Centre, University of Oslo, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Posthuma D; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU Amsterdam, Amsterdam, the Netherlands. d.posthuma@vu.nl.; Department of Child and Adolescent Psychiatry and Pediatric Psychology, Section Complex Trait Genetics, Amsterdam Neuroscience, Vrije Universiteit Medical Center, Amsterdam University Medical Center, Amsterdam, the Netherlands. d.posthuma@vu.nl.

Publikováno v: Nature genetics [Nat Genet] 2022 Jul; Vol. 54 (7), pp. 1062.

Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease.

Autor: Wightman DP; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU Amsterdam, Amsterdam, the Netherlands., Jansen IE; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU Amsterdam, Amsterdam, the Netherlands., Savage JE; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU Amsterdam, Amsterdam, the Netherlands., Shadrin AA; NORMENT Centre, University of Oslo, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Bahrami S; NORMENT Centre, University of Oslo, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Holland D; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA., Rongve A; Department of Research and Innovation, Helse Fonna, Haugesund Hospital, Haugesund, Norway.; The University of Bergen, Institute of Clinical Medicine (K1), Bergen, Norway., Børte S; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Research and Communication Unit for Musculoskeletal Health (FORMI), Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway., Winsvold BS; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.; Department of Neurology, Oslo University Hospital, Oslo, Norway., Drange OK; Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Division of Mental Health Care, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Martinsen AE; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway., Skogholt AH; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Willer C; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA., Bråthen G; Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Neurology and Clinical Neurophysiology, University Hospital of Trondheim, Trondheim, Norway.; Department of Geriatrics, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway., Bosnes I; Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Psychiatry, Hospital Namsos, Nord-Trøndelag Health Trust, Namsos, Norway., Nielsen JB; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Fritsche LG; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA., Thomas LF; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Pedersen LM; Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway., Gabrielsen ME; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway., Johnsen MB; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Research and Communication Unit for Musculoskeletal Health (FORMI), Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway., Meisingset TW; Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Neurology and Clinical Neurophysiology, University Hospital of Trondheim, Trondheim, Norway., Zhou W; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA., Proitsi P; Institute of Psychiatry Psychology and Neurosciences, King's College London, London, UK., Hodges A; Institute of Psychiatry Psychology and Neurosciences, King's College London, London, UK., Dobson R; Department of Biostatistics and Health Informatics, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King's College London, London, UK.; NIHR Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London, London, UK.; Health Data Research UK London, University College London, London, UK.; Institute of Health Informatics, University College London, London, UK.; NIHR Biomedical Research Centre at University College London Hospitals NHS Foundation Trust, London, UK., Velayudhan L; Institute of Psychiatry Psychology and Neurosciences, King's College London, London, UK., Heilbron K; 23andMe Inc., Sunnyvale, CA, USA., Auton A; 23andMe Inc., Sunnyvale, CA, USA., Sealock JM; Division of Genetic Medicine, Department of Medicine Vanderbilt University Medical Center Nashville, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Davis LK; Division of Genetic Medicine, Department of Medicine Vanderbilt University Medical Center Nashville, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Reynolds CA; Department of Psychology, University of California-Riverside, Riverside, CA, USA., Karlsson IK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Institute of Gerontology and Aging Research Network - Jönköping (ARN-J), School of Health and Welfare, Jönköping University, Jönköping, Sweden., Magnusson S; deCODE Genetics/Amgen, Reykjavik, Iceland., Stefansson H; deCODE Genetics/Amgen, Reykjavik, Iceland., Thordardottir S; Department of Geriatric Medicine, Landspitali University Hospital, Reykjavik, Iceland., Jonsson PV; Department of Geriatric Medicine, Landspitali University Hospital, Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Snaedal J; Department of Geriatric Medicine, Landspitali University Hospital, Reykjavik, Iceland., Zettergren A; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, Centre for Ageing and Health (AGECAP) at the University of Gothenburg, Gothenburg, Sweden., Skoog I; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, Centre for Ageing and Health (AGECAP) at the University of Gothenburg, Gothenburg, Sweden.; Region Västra Götaland, Sahlgrenska University Hospital, Psychiatry, Cognition and Old Age Psychiatry Clinic, Gothenburg, Sweden., Kern S; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, Centre for Ageing and Health (AGECAP) at the University of Gothenburg, Gothenburg, Sweden.; Region Västra Götaland, Sahlgrenska University Hospital, Psychiatry, Cognition and Old Age Psychiatry Clinic, Gothenburg, Sweden., Waern M; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy, Centre for Ageing and Health (AGECAP) at the University of Gothenburg, Gothenburg, Sweden.; Region Västra Götaland, Sahlgrenska University Hospital, Psychosis Clinic, Gothenburg, Sweden., Zetterberg H; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; UK Dementia Research Institute at UCL, London, UK.; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden., Blennow K; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden., Stordal E; Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Psychiatry, Hospital Namsos, Nord-Trøndelag Health Trust, Namsos, Norway., Hveem K; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Center, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway., Zwart JA; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; K. G. Jebsen Center for Genetic Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway., Athanasiu L; NORMENT Centre, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Selnes P; Department of Neurology, Akershus University Hospital, Lørenskog, Norway., Saltvedt I; Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Geriatrics, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway., Sando SB; Department of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Neurology and Clinical Neurophysiology, University Hospital of Trondheim, Trondheim, Norway., Ulstein I; Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway., Djurovic S; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway.; NORMENT, Department of Clinical Science, University of Bergen, Bergen, Norway., Fladby T; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Neurology, Akershus University Hospital, Lørenskog, Norway., Aarsland D; Institute of Psychiatry Psychology and Neurosciences, King's College London, London, UK.; Centre of Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway., Selbæk G; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Geriatric Medicine, Oslo University Hospital, Oslo, Norway.; Norwegian National Advisory Unit on Ageing and Health, Vestfold Hospital Trust, Tønsberg, Norway., Ripke S; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Psychiatry and Psychotherapy, Charité-Universitätsmedizin, Berlin, Germany., Stefansson K; deCODE Genetics/Amgen, Reykjavik, Iceland., Andreassen OA; NORMENT Centre, University of Oslo, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway., Posthuma D; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU Amsterdam, Amsterdam, the Netherlands. d.posthuma@vu.nl.; Department of Child and Adolescent Psychiatry and Pediatric Psychology, Section Complex Trait Genetics, Amsterdam Neuroscience, Vrije Universiteit Medical Center, Amsterdam University Medical Center, Amsterdam, the Netherlands. d.posthuma@vu.nl.

Publikováno v: Nature genetics [Nat Genet] 2021 Dec; Vol. 53 (12), pp. 1722.