Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states

Autor: Wang Liang, Subramanian Subbaya, Cunningham Julie M, Boardman Lisa A, Riska Shaun M, Morlan Bruce W, Silverstein Kevin AT, Oberg Ann L, Thayanithy Venugopal, Borralho Pedro M, French Amy J, Sarver Aaron L, Smyrk Tom C, Rodrigues Cecilia MP, Thibodeau Stephen N, Steer Clifford J

Publikováno v: BMC Cancer, Vol 9, Iss 1, p 401 (2009)

Abstract Background Colon cancer arises from the accumulation of multiple genetic and epigenetic alterations to normal colonic tissue. microRNAs (miRNAs) are small, non-coding regulatory RNAs that post-transcriptionally regulate gene expression. Diff

Externí odkaz: https://doaj.org/article/b75137a880584987bae6c62cd76f6d15

Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database

Autor: Thompson, Bryony A, Spurdle, Amanda B, Plazzer, John-Paul, Greenblatt, Marc S, Akagi, Kiwamu, Al-Mulla, Fahd, Bapat, Bharati, Bernstein, Inge, Capellá, Gabriel, den Dunnen, Johan T, du Sart, Desiree, Fabre, Aurelie, Farrell, Michael P, Farrington, Susan M, Frayling, Ian M, Frebourg, Thierry, Goldgar, David E, Heinen, Christopher D, Holinski-Feder, Elke, Kohonen-Corish, Maija, Robinson, Kristina Lagerstedt, Leung, Suet Yi, Martins, Alexandra, Moller, Pal, Morak, Monika, Nystrom, Minna, Peltomaki, Paivi, Pineda, Marta, Qi, Ming, Ramesar, Rajkumar, Rasmussen, Lene Juel, Royer-Pokora, Brigitte, Scott, Rodney J, Sijmons, Rolf, Tavtigian, Sean V, Tops, Carli M, Weber, Thomas, Wijnen, Juul, Woods, Michael O, Macrae, Finlay, Genuardi, Maurizio, Castillejo, Adela, Sexton, Adrienne, Chan, Anthony K W, Viel, Alessandra, Blanco, Amie, French, Amy, Laner, Andreas, Wagner, Anja, van den Ouweland, Ans, Mensenkamp, Arjen, Payá, Artemio, Betz, Beate, Redeker, Bert, Smith, Betsy, Espenschied, Carin, Cummings, Carole, Engel, Christoph, Fornes, Claudia, Valenzuela, Cristian, Alenda, Cristina, Buchanan, Daniel, Barana, Daniela, Konstantinova, Darina, Cairns, Dianne, Glaser, Elizabeth, Silva, Felipe, Lalloo, Fiona, Crucianelli, Francesca, Hogervorst, Frans, Casey, Graham, Tomlinson, Ian, Blanco, Ignacio, Villar, Isabel López, Garcia-Planells, Javier, Bigler, Jeanette, Shia, Jinru, Martinez-Lopez, Joaquin, Gille, Johan J P, Hopper, John, Potter, John, Soto, José Luis, Kantelinen, Jukka, Ellis, Kate, Mann, Kirsty, Varesco, Liliana, Zhang, Liying, Le Marchand, Loic, Marafie, Makia J, Nordling, Margareta, Tibiletti, Maria Grazia, Kahan, Mariano Ariel, Ligtenberg, Marjolijn, Clendenning, Mark, Jenkins, Mark, Speevak, Marsha, Digweed, Martin, Kloor, Matthias, Hitchins, Megan, Myers, Megan, Aronson, Melyssa, Valentin, Mev Dominguez, Kutsche, Michael, Parsons, Michael, Walsh, Michael, Kansikas, Minttu, Zahary, Mohd Nizam, Pedroni, Monica, Heider, Nao, Poplawski, Nicola, Rahner, Nils, Lindor, Noralane M, Sala, Paola, Nan, Peng, Propping, Peter, Newcomb, Polly, Sarin, Rajiv, Haile, Robert, Hofstra, Robert, Ward, Robyn, Tricarico, Rossella, Bacares, Ruben, Young, Sean, Chialina, Sergio, Kovalenko, Serguei, Gunawardena, Shanaka R, Moreno, Sira, Ho, Siu Lun, Yuen, Siu Tsan, Thibodeau, Stephen N, Gallinger, Steve, Burnett, Terrilea, Teitsch, Therese, Chan, Tsun Leung, Smyrk, Tom, Cranston, Treena, Psofaki, Vasiliki, Steinke-Lange, Verena, Barbera, Victor-Manuel

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Genetics
Nature Genetics, Nature Publishing Group, 2014, 46 (2), pp.107-115. ⟨10.1038/ng.2854⟩
Nature Genetics, 46(2), 107
Nature Genetics, 46, 107-15
Nature genetics, 46(2), 107-115. Nature Publishing Group
Nature Genetics, 46(2), 107-+. Nature Publishing Group
Thompson, B A, Spurdle, A B, Plazzer, J-P, Greenblatt, M S, Akagi, K, Al-Mulla, F, Bapat, B, Bernstein, I, Capellá, G, den Dunnen, J T, du Sart, D, Fabre, A, Farrell, M P, Farrington, S M, Frayling, I M, Frebourg, T, Goldgar, D E, Heinen, C D, Holinski-Feder, E, Kohonen-Corish, M, Robinson, K L, Leung, S Y, Martins, A, Moller, P, Morak, M, Nystrom, M, Peltomaki, P, Pineda, M, Qi, M, Ramesar, R, Rasmussen, L J, Royer-Pokora, B, Scott, R J, Sijmons, R, Tavtigian, S V, Tops, C M, Weber, T, Wijnen, J, Woods, M O, Macrae, F, Genuardi, M, Castillejo, A, Sexton, A, Chan, A K W, Viel, A, Blanco, A, French, A, Laner, A, Wagner, A, van den Ouweland, A & on behalf of InSiGHT 2014, ' Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database ', Nature Genetics, vol. 46, no. 2, pp. 107-115 . https://doi.org/10.1038/ng.2854
Dipòsit Digital de la UB
Universidad de Barcelona
Nature Genetics, 46, 2, pp. 107-15
Nature Genetics, 46(2), 107-115.e2. Nature Publishing Group

Contains fulltext : 138857.pdf (Publisher’s version ) (Closed access) The clinical classification of hereditary sequence variants identified in disease-related genes directly affects clinical management of patients and their relatives. The Internat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86466f033db6930362efd3088b4995cf
https://hdl.handle.net/1765/58187

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Natural history of colorectal cancer in hereditary nonpolyposis colorectal cancer (Lynch syndromes I and II).

Autor: Lynch, Henry T., Watson, Patrice, Lanspa, Stephen J., Marcus, Joseph, Smyrk, Tom, Fitzgibbons Jr, Robert J., Kriegler, Mary, Lynch, Jane F.

Publikováno v: Diseases of the Colon & Rectum; Jun1988, Vol. 31 Issue 6, p439-444, 6p