Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Smriti Parashar"'
Autor:
Smriti Parashar, Ravi Chidambaram, Shuliang Chen, Christina R Liem, Eric Griffis, Gerard G Lambert, Nathan C Shaner, Matthew Wortham, Jesse C Hay, Susan Ferro-Novick
Publikováno v:
eLife, Vol 10 (2021)
The endoplasmic reticulum (ER) is composed of sheets and tubules. Here we report that the COPII coat subunit, SEC24C, works with the long form of the tubular ER-phagy receptor, RTN3, to target dominant-interfering mutant proinsulin Akita puncta to ly
Externí odkaz:
https://doaj.org/article/bfdc35449f78485fab17dbdda6923c5b
Publikováno v:
Current Traditional Medicine. 9
Abstract: Nature always has enough spirit and resilience to transform our limited vision. Herbal medicines include products prepared from natural herbs which are employed to treat several diseases. In India, about 80% of drugs are of herbal origin. N
Autor:
Smriti Parashar, Susan Ferro-Novick
Publikováno v:
eLife
Autophagy
Autophagy
The endoplasmic reticulum (ER) forms a contiguous network of tubules and sheets. When errors in protein folding occur, misfolded proteins accumulate in the ER. Proteostasis can be restored by ER quality control pathways. Reticulophagy is an ER qualit
Autor:
Matthew Wortham, Eric R. Griffis, Susan Ferro-Novick, Smriti Parashar, Ravi Chidambaram, Shuliang Chen, Christina R Liem, Gerard G. Lambert, Nathan C. Shaner, Jesse C. Hay
Publikováno v:
eLife, Vol 10 (2021)
The endoplasmic reticulum (ER) is composed of sheets and tubules. Here we report that the COPII coat subunit, SEC24C, works with the long form of the tubular ER-phagy receptor, RTN3, to target dominant-interfering mutant proinsulin Akita puncta to ly
Autor:
Nathan C. Shaner, Gerard G. Lambert, Shuliang Chen, Eric R. Griffis, Matthew Wortham, Jesse C. Hay, Ravi Chidambaram, Smriti Parashar, Susan Ferro-Novick, Christina R Liem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::041a945121b006d5cd3aec582a62f707
https://doi.org/10.7554/elife.71642.sa2
https://doi.org/10.7554/elife.71642.sa2
Autor:
Hesso Farhan, Jeffrey L. Brodsky, Muhammad Zahoor, Patrick G. Needham, Susan Ferro-Novick, Smriti Parashar, Muriel Mari, Ming Zhu, Hsuan-Chung Ho, Fulvio Reggiori, Shuliang Chen, Yixian Cui
Publikováno v:
Science, 365(6448), 53-60. AMER ASSOC ADVANCEMENT SCIENCE
ER-phagy keeps cells healthy In eukaryotic cells, about one-third of all proteins are targeted to the endoplasmic reticulum (ER), which serves as a hub for secretory protein traffic and quality control. Cui et al. studied a protein known as Lst1 in y
Autor:
Yixian Cui, Muriel Mari, Smriti Parashar, Susan Ferro-Novick, Dongmei Liu, Fulvio Reggiori, Peter Novick, Shuliang Chen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 117, iss 31
Proceedings of the National Academy of Sciences of the United States of America, 117(31), 18530-18539. NATL ACAD SCIENCES
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America, 117(31), 18530-18539. NATL ACAD SCIENCES
Proc Natl Acad Sci U S A
Endoplasmic reticulum (ER) macroautophagy (hereafter called ER-phagy) uses autophagy receptors to selectively degrade ER domains in response to starvation or the accumulation of aggregation-prone proteins. Autophagy receptors package the ER into auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02197d3863f584e720adcb2bfa20dfd2
https://escholarship.org/uc/item/5k59g029
https://escholarship.org/uc/item/5k59g029
Autor:
Disha Arora, Lokesh Deb, Rupesh K. Gautam, Smriti Parashar, Gayatri Thapa, Bhumika Gurung, K. Roy
Publikováno v:
Indian Journal of Pharmaceutical Sciences. 82
Rheumatoid Arthritis is a systemic autoimmune disease characterized by chronic, inflammatory condition. The adverse effects of long-term use of presently available anti-arthritic or non-steroidal anti-inflammatory drugs are gastrointestinal symptoms,
Publikováno v:
Autophagy
Endoplasmic reticulum (ER) homeostasis is maintained by the removal of misfolded ER proteins via different quality control pathways. Aggregation-prone proteins, including certain disease-linked proteins, are resistant to conventional ER degradation p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c2744c77b4dc6246d3963c28a4150dd
https://europepmc.org/articles/PMC6984482/
https://europepmc.org/articles/PMC6984482/
Autor:
Smriti Parashar, Amitabha Mukhopadhyay
Publikováno v:
Journal of Biological Chemistry. 292:12111-12125
Metalloprotease gp63 (Leishmania donovani gp63 (Ldgp63)) is a critical virulence factor secreted by Leishmania. However, how newly synthesized Ldgp63 exits the endoplasmic reticulum (ER) and is secreted by this parasite is unknown. Here, we cloned, e