Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Smriti Hoda"'
Autor:
Luopin Wang, Aryamav Pattnaik, Subhransu Sekhar Sahoo, Ella G. Stone, Yuxin Zhuang, Annaleigh Benton, Md Tajmul, Srishti Chakravorty, Deepika Dhawan, My An Nguyen, Isabella Sirit, Kyle Mundy, Christopher J. Ricketts, Marco Hadisurya, Garima Baral, Samantha L. Tinsley, Nicole L. Anderson, Smriti Hoda, Scott D. Briggs, Hristos Z. Kaimakliotis, Brittany L. Allen-Petersen, W. Andy Tao, W. Marston Linehan, Deborah W. Knapp, Jason A. Hanna, Matthew R. Olson, Behdad Afzali, Majid Kazemian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Correctly identifying perturbed biological pathways is a critical step in uncovering basic disease mechanisms and developing much-needed therapeutic strategies. However, whether current tools are optimal for unbiased discovery of relevant pa
Externí odkaz:
https://doaj.org/article/37aa067c964242d3a201f09242539e89
Autor:
Debasmita Saha, Justin B. Gregor, Smriti Hoda, Katharine E. Eastman, Victor A. Gutierrez-Schultz, Mindy Navarrete, Jennifer H. Wisecaver, Scott D. Briggs
Publikováno v:
mSphere, Vol 9, Iss 11 (2024)
ABSTRACT Candida glabrata exhibits innate resistance to azole antifungal drugs but also has the propensity to rapidly develop clinical drug resistance. Azole drugs, which target Erg11, is one of the major classes of antifungals used to treat Candida
Externí odkaz:
https://doaj.org/article/83e0839b577a446791841693a000dfe5
Autor:
Justin B. Gregor, Victor A. Gutierrez-Schultz, Smriti Hoda, Kortany M. Baker, Debasmita Saha, Madeline G. Burghaze, Cynthia Vazquez, Kendra E. Burgei, Scott D. Briggs
Publikováno v:
mSphere, Vol 8, Iss 6 (2023)
ABSTRACTThe World Health Organization recently published the first list of priority fungal pathogens highlighting multiple Candida species, including Candida glabrata, Candida albicans, and Candida auris. However, prior studies in these pathogens hav
Externí odkaz:
https://doaj.org/article/a97369fb80754a18aa5fd5c711b12837
Autor:
Kedric L. Milholland, Justin B. Gregor, Smriti Hoda, Soledad Píriz-Antúnez, Encarnación Dueñas-Santero, Bao Gia Vu, Krishna P. Patel, W. Scott Moye-Rowley, Carlos R. Vázquez de Aldana, Jaime Correa-Bordes, Scott D. Briggs, Mark C. Hall
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT A variety of inducible protein degradation (IPD) systems have been developed as powerful tools for protein functional characterization. IPD systems provide a convenient mechanism for rapid inactivation of almost any target protein of interes
Externí odkaz:
https://doaj.org/article/c02846f684424772b8b8dab266c33330
Autor:
Kedric L. Milholland, Ahmed AbdelKhalek, Kortany M. Baker, Smriti Hoda, Andrew G. DeMarco, Noelle H. Naughton, Angela N. Koeberlein, Gabrielle R. Lorenz, Kartikan Anandasothy, Antonio Esperilla-Muñoz, Sanjeev K. Narayanan, Jaime Correa-Bordes, Scott D. Briggs, Mark C. Hall
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The Cdc14 phosphatase family is highly conserved in fungi. In Saccharomyces cerevisiae, Cdc14 is essential for down-regulation of cyclin-dependent kinase activity at mitotic exit. However, this essential function is not broadly conserved and requires
Externí odkaz:
https://doaj.org/article/8648e86a4d7e443ca24a03550a6e2b25
Autor:
Kedric L. Milholland, Ahmed AbdelKhalek, Kortany M. Baker, Smriti Hoda, Andrew G. DeMarco, Noelle H. Naughton, Angela N. Koeberlein, Gabrielle R. Lorenz, Kartikan Anandasothy, Antonio Esperilla-Muñoz, Sanjeev K. Narayanan, Jaime Correa-Bordes, Scott D. Briggs, Mark C. Hall
The Cdc14 phosphatase family is highly conserved in fungi. InSaccharomyces cerevisiae,Cdc14 is essential for down-regulation of cyclin-dependent kinase activity at mitotic exit. However, this essential function is not broadly conserved and requires a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2785420e30cab6244cb83e58e81eb35f
https://doi.org/10.1101/2022.09.29.510203
https://doi.org/10.1101/2022.09.29.510203
Autor:
Kortany M. Baker, Smriti Hoda, Debasmita Saha, Justin B. Gregor, Livia Georgescu, Nina D. Serratore, Yueping Zhang, Lizhi Cheng, Nadia A. Lanman, Scott D. Briggs
Publikováno v:
Antimicrob Agents Chemother
Fungal infections are a major health concern because of limited antifungal drugs and development of drug resistance. Candida can develop azole drug resistance by overexpression of drug efflux pumps or mutating ERG11, the target of azoles. However, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9657b7377e2e377eca704ef7d0ee64
https://europepmc.org/articles/PMC9112889/
https://europepmc.org/articles/PMC9112889/
Autor:
Scott D. Briggs, Kortany M. Baker, Debasmita Saha, Smriti Hoda, Livia Georgescu, Nina D. Serratore, Nadia A. Lanman, Yueping Zhang
Candida glabratais an opportunistic pathogen that has developed the ability to adapt and thrive under azole treated conditions. The common mechanisms that can result inCandidadrug resistance are due to mutations or overexpression of the drug efflux p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae738483dce9de7b4ef21aa86b7c2c7f
https://doi.org/10.1101/2021.11.17.469015
https://doi.org/10.1101/2021.11.17.469015
Autor:
Smriti Hoda, Elizabeth Greguske
Publikováno v:
The Journal of Immunology. 198:158.28-158.28
Discovery of antibiotics has revolutionized the 20th century medicine, and has been one of the most potent methods to treat bacterial infections. Before antibiotics, infectious disease was the number one killer worldwide, in fact, bacterial infection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a3ba4eae1f53b5d033f7e9ad8c1953c
https://doi.org/10.4049/jimmunol.198.supp.158.28
https://doi.org/10.4049/jimmunol.198.supp.158.28