Zobrazeno 1 - 10
of 410
pro vyhledávání: '"Smorodina, A. A."'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-24 (2024)
Abstract Transmembrane potassium ion channels are crucial for ion transport, metabolism, and signaling, and serve as promising targets for anti-cancer therapies. However, their hydrophobic transmembrane nature requires detergents, posing a major bott
Externí odkaz:
https://doaj.org/article/100f097f8cc24967b7c0ad74b788caef
Autor:
Smorodina, Eva1 (AUTHOR), Tao, Fei2 (AUTHOR), Qing, Rui2 (AUTHOR), Yang, Steve3 (AUTHOR), Zhang, Shuguang4 (AUTHOR) shuguang@mit.edu
Publikováno v:
Scientific Reports. 11/15/2024, Vol. 14 Issue 1, p1-24. 24p.
Autor:
Habib Bashour, Eva Smorodina, Matteo Pariset, Jahn Zhong, Rahmad Akbar, Maria Chernigovskaya, Khang Lê Quý, Igor Snapkow, Puneet Rawat, Konrad Krawczyk, Geir Kjetil Sandve, Jose Gutierrez-Marcos, Daniel Nakhaee-Zadeh Gutierrez, Jan Terje Andersen, Victor Greiff
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-25 (2024)
Abstract Designing effective monoclonal antibody (mAb) therapeutics faces a multi-parameter optimization challenge known as “developability”, which reflects an antibody’s ability to progress through development stages based on its physicochemic
Externí odkaz:
https://doaj.org/article/54691d3c1e42401d80a1f1a4a75878b7
Autor:
Balaev, D.A. a, ⁎, Knyazev, YuV. a, Semenov, S.V. a, Dubrovskiy, A.A. a, Lasukov, A.I. a, b, Skorobogatov, S.A. a, Smorodina, E.D. a, b, Kirillov, V.L. c, Martyanov, O.N. c
Publikováno v:
In Ceramics International January 2025 51(1):650-663
Autor:
Riccabona, Jakob R., Spoendlin, Fabian C., Fischer, Anna-Lena M., Loeffler, Johannes R., Quoika, Patrick K., Jenkins, Timothy P., Ferguson, James A., Smorodina, Eva, Laustsen, Andreas H., Greiff, Victor, Forli, Stefano, Ward, Andrew B., Deane, Charlotte M., Fernández-Quintero, Monica L.
Publikováno v:
In Structure 7 November 2024 32(11):2147-2159
Autor:
Khan, Asif, Cowen-Rivers, Alexander I., Grosnit, Antoine, Deik, Derrick-Goh-Xin, Robert, Philippe A., Greiff, Victor, Smorodina, Eva, Rawat, Puneet, Dreczkowski, Kamil, Akbar, Rahmad, Tutunov, Rasul, Bou-Ammar, Dany, Wang, Jun, Storkey, Amos, Bou-Ammar, Haitham
Antibodies are canonically Y-shaped multimeric proteins capable of highly specific molecular recognition. The CDRH3 region located at the tip of variable chains of an antibody dominates antigen-binding specificity. Therefore, it is a priority to desi
Externí odkaz:
http://arxiv.org/abs/2201.12570
Autor:
Lorenzo Federico, Brandon Malone, Simen Tennøe, Viktoriia Chaban, Julie Røkke Osen, Murat Gainullin, Eva Smorodina, Hassen Kared, Rahmad Akbar, Victor Greiff, Richard Stratford, Trevor Clancy, Ludvig Andre Munthe
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/71696a78c10c4e30a836d19c193d086e
Autor:
Knyazev, Yuriy V., Kirillov, Viktor L., Krasikov, Aleksandr A., Skorobogatov, Stanislav A., Velikanov, Dmitry A., Volochaev, Mikhail N., Smorodina, Ekaterina D., Bayukov, Oleg A., Martyanov, Oleg N., Balaev, Dmitry A.
Publikováno v:
In Ceramics International November 2024
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0289644 (2024)
Glutamate transporters play key roles in nervous physiology by modulating excitatory neurotransmitter levels, when malfunctioning, involving in a wide range of neurological and physiological disorders. However, integral transmembrane proteins includi
Externí odkaz:
https://doaj.org/article/23e6c85010574c9a85f92ddbae025454
Publikováno v:
QRB Discovery, Vol 5 (2024)
Human ATP-binding cassette (ABC) transporters are one of the largest families of membrane proteins and perform diverse functions. Many of them are associated with multidrug resistance that often results in cancer treatment with poor outcomes. Here, w
Externí odkaz:
https://doaj.org/article/52e885aef2ec4996bad45e082b5bfb27