Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Smooth muscle myosin heavy chain"'
Autor:
Muhammad Ashfaq Khan, Julian Fischer, Leon Harrer, Fabian Schwiering, Dieter Groneberg, Andreas Friebe
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The combination of lineage tracing and immunohistochemistry has helped to identify subpopulations and fate of hepatic stellate cells (HSC) in murine liver. HSC are sinusoidal pericytes that act as myofibroblast precursors after liver injury.
Externí odkaz:
https://doaj.org/article/091f823e807f4d8987d870c715dd14b5
Akademický článek
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Autor:
Sumati Ram-Mohan, Ramaswamy Krishnan, Joseph D. Brain, Jonathan A. Cohen, Carolina Martines, Guang Li, Yan Bai, Xingbin Ai
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Precision-cut lung slices (PCLS) are ideal for measuring small airway contraction. However, these measurements are currently limited to acute exposure scenarios that typically last a few minutes to a few hours. Using an insulin-supplemented culture m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d8dd7bce3a92f5e5a92700633131dc
http://link.springer.com/article/10.1038/s41598-020-63225-y
http://link.springer.com/article/10.1038/s41598-020-63225-y
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • Stat3, a major signaling molecule for proinflammatory cytokines including IL-6, was activated both in inflammatory cells and in SMC in the aortic walls of human AD and mouse AD model. • SMC-specific deletion of S
Highlights • Stat3, a major signaling molecule for proinflammatory cytokines including IL-6, was activated both in inflammatory cells and in SMC in the aortic walls of human AD and mouse AD model. • SMC-specific deletion of S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97e00503172b3927b073b90216d64ddb
https://pubmed.ncbi.nlm.nih.gov/32140621
https://pubmed.ncbi.nlm.nih.gov/32140621
Autor:
Mengxue Zhang, Go Urabe, Christopher Little, Lian-Wang Guo, Yitao Huang, Alycia Kent, Bowen Wang, K. Craig Kent
Publikováno v:
JACC: Basic to Translational Science
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 782-795 (2018)
JACC: Basic to Translational Science, Vol 3, Iss 6, Pp 782-795 (2018)
Visual Abstract
Highlights • Distinct from other histone deacetylases, HDAC6 primarily resides in the cytosol. • Unexpectedly, HDAC6-selective inhibition (or silencing) enhances the nuclear activity of SRF. • HDAC6 inhibition elevates acet
Highlights • Distinct from other histone deacetylases, HDAC6 primarily resides in the cytosol. • Unexpectedly, HDAC6-selective inhibition (or silencing) enhances the nuclear activity of SRF. • HDAC6 inhibition elevates acet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b88948908b31bd909f037f62bf67192c
http://europepmc.org/articles/PMC6314972
http://europepmc.org/articles/PMC6314972
Publikováno v:
Journal of Genetics. 97:469-476
Smooth muscle myosin heavy chain (SM-MHC) is exclusively expresses in smooth muscle, which takes part in smooth muscle cell contraction. Here, we used an insertional mutation mouse whose heavy polypeptide 11 (Myh11) gene has been disrupted and no SM-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1e8d4cd37d97f75f0fad18f6665d7a1
https://doi.org/10.1007/s12041-018-0930-z
https://doi.org/10.1007/s12041-018-0930-z
Akademický článek
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Publikováno v:
Heart & Lung. 44:205-208
The purpose of this study was to identify biological markers for early diagnosis of acute aortic dissection (AAD).76 patients presented to the emergency room with acute chest pain within 6 h of occurrence were recruited for this study, and AAD diagno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0f55712d9181a0a7a242da82fa57218
https://doi.org/10.1016/j.hrtlng.2015.01.006
https://doi.org/10.1016/j.hrtlng.2015.01.006
Publikováno v:
Pharmacology & Therapeutics
The recent development of tissue engineering provides exciting new perspectives for the replacement of failing organs and the repair of damaged tissues. Perivascular cells, including vascular smooth muscle cells, pericytes and other tissue specific p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d9f59a9cb988397455ad23e3d587a9ba
https://pubmed.ncbi.nlm.nih.gov/27889329
https://pubmed.ncbi.nlm.nih.gov/27889329