Výsledky vyhledávání - "Smitha Patiyil Menon"

Interim results of an ongoing phase 1/2a study of HPN328, a tri-specific, half-life extended, DLL3-targeting, T-cell engager, in patients with small cell lung cancer and other neuroendocrine cancers

Autor: Melissa Lynne Johnson, Grace K. Dy, Hirva Mamdani, Afshin Dowlati, Adam Jacob Schoenfeld, Jose Maria Pacheco, Rachel E. Sanborn, Smitha Patiyil Menon, Linda Santiago, Yifah Yaron, Himisha Beltran

Publikováno v: Journal of Clinical Oncology. 40:8566-8566

8566 Background: HPN328 is a delta like canonical Notch ligand 3 (DLL3)-targeting T-cell engager (TCE) derived from the TriTAC platform, designed to minimize off-target toxicities. HPN328 contains 3 binding domains, engineered to redirect T cells to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b466d4fd30707ad081034e31174b4b0d
https://doi.org/10.1200/jco.2022.40.16_suppl.8566

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