Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Smith Trevor Stanley"'
Autor:
Jonathan Clark, Veronique Juvin, Michael J.O. Wakelam, Fredrik Karpe, Smith Trevor Stanley, Phillip T. Hawkins, Len R. Stephens, Karen E. Anderson
Publikováno v:
Nature methods
Nature Methods
Nature Methods; Vol 8
Nature Methods
Nature Methods; Vol 8
Class I phosphoinositide-3-kinase (PI3K) isoforms generate the intracellular signaling lipid, phosphatidylinositol(3,4,5)trisphosphate (PtdIns(3,4,5)P 3). PtdIns(3,4,5)P 3 regulates major aspects of cellular behavior, and the use of both genetic and
Autor:
Armando A. Genazzani, Michele Di Stefano, Elisabetta Babetto, Lucie Janeckova, Bogdan Beirowski, Richard A. Billington, Smith Trevor Stanley, Michael P. Coleman, Robert Hartley, Anna L. Wilbrey, Laura Conforti, Giulio Magni, Robert Adalbert, Francesca Mazzola, Giacomo Morreale, Jonathan Gilley, Richard R. Ribchester
Publikováno v:
Conforti, L, Wilbrey, A, Morreale, G, Janeckova, L, Beirowski, B, Adalbert, R, Mazzola, F, Di Stefano, M, Hartley, R, Babetto, E, Smith, T, Gilley, J, Billington, R A, Genazzani, A A, Ribchester, R R, Magini, G & Coleman, M P 2009, ' Wld(S) protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice ', Journal of Cell Biology, vol. 184, no. 4, pp. 491-500 . https://doi.org/10.1083/jcb.200807175
The Journal of Cell Biology
The Journal of Cell Biology
The slow Wallerian degeneration (WldS) protein protects injured axons from degeneration. This unusual chimeric protein fuses a 70–amino acid N-terminal sequence from the Ube4b multiubiquitination factor with the nicotinamide adenine dinucleotide–
Autor:
Smith Trevor Stanley, Vincenzina Reale, Peter D. Evans, Deepak Srivastava, Esther J. Yu, Heather Chatwin, Karen Kennedy, Maureen Hamon
Publikováno v:
The Journal of Neuroscience. 25:6145-6155
Nongenomic response pathways mediate many of the rapid actions of steroid hormones, but the mechanisms underlying such responses remain controversial. In some cases, cell-surface expression of classical nuclear steroid receptors has been suggested to
Autor:
Munn Edward Albert, Fiona M. James, Smith Trevor Stanley, Fiona C. Smith, Howard Smith, Stuart J. Andrews
Publikováno v:
Parasite Immunology. 19:243-248
As part of a systematic examination of the protective epitopes on H11, groups of sheep were vaccinated with preparations of purified H11 used untreated (group A), or progressively denatured (linearized) by incubation with sodium dodecyl sulphate (SDS
Autor:
W. David Smith, Smith Trevor Stanley, Margaret Graham, W. John Coadwell, Howard Smith, Danielle Mcmichael-Phillips, David P. Knox, Joanne J Oliver, Munn Edward Albert, Susan Elizabeth Newton
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 1338:295-306
In order to characterise the integral membrane glycoprotein H11 from the intestinal microvilli of the nematode Haemonchus contortus, cDNA libraries prepared using mRNA from adult worms from the UK and Australia were immunoscreened with anti-H11 sera.
Autor:
Munn Edward Albert, Margaret Graham, Smith Trevor Stanley, Angela S. Tavernor, Cordelia F. Langford
Publikováno v:
Parasite Immunology. 14:645-655
Six Dorset Horn lambs were each vaccinated at age 7 weeks and 9 weeks with 50 micrograms of glycosylated integral membrane proteins, particularly enriched in the protein H11 from the intestinal brush border of adult Haemonchus. At 11 weeks of age the
VCP binding influences intracellular distribution of the slow Wallerian degeneration protein, Wld(S)
Autor:
David J. A. Wyllie, Richard R. Ribchester, Michael P. Coleman, Thomas M. Wishart, Giacomo Morreale, Jane E. Haley, Bogdan Beirowski, Anna L. Wilbrey, Smith Trevor Stanley, Laura Conforti, Elisabetta Babetto, Thomas H. Gillingwater, Robert Adalbert
Publikováno v:
Molecular and cellular neurosciences. 38(3)
Wallerian degeneration slow (Wld(S)) mice express a chimeric protein that delays axonal degeneration. The N-terminal domain (N70), which is essential for axonal protection in vivo, binds valosin-containing protein (VCP) and targets both Wld(S) and VC
Autor:
Lynda A. Sellers, Smith Trevor Stanley, Piers C. Emson, Eric B. Keverne, Jing Xia, David Oxley
Publikováno v:
The European journal of neuroscience. 24(12)
The G protein-coupled pheromone receptor neurons (V1R and V2R) of the vomeronasal organ (VNO) are continually replaced throughout the lifetime of the mouse. Moreover, active signalling of V2Rs via the transient receptor potential 2(TRPC2) channel is
Autor:
Hidde L. Ploegh, Maureen Hamon, Svetlana Hamm, Peter J. Kilshaw, Huib Ovaa, Smith Trevor Stanley, Stefan Bauer, Paul C. Evans
Publikováno v:
The Biochemical journal. 378(Pt 3)
Ubiquitination regulates the stability and/or activity of numerous cellular proteins. The corollary is that de-ubiquitinating enzymes, which 'trim' polyubiquitin chains from specific substrate proteins, play key roles in controlling fundamental cellu
Autor:
Paul C. Evans, Marja Kreike, Smith Trevor Stanley, David F. Burke, Peter J. Kilshaw, Meng-Jiun Lai, Mark G. Williams, Karen Heyninck, Rudi Beyaert, Tom L. Blundell
Publikováno v:
The Journal of biological chemistry. 278(25)
A previous report from this laboratory described two novel proteins that have sequence similarity to A20, a negative regulator of NF-kappaB (Evans, P. C., Taylor, E. R., Coadwell, J., Heyninck, K., Beyaert, R., and Kilshaw, P. J. (2001) Biochem. J. 3