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Initiation of long-acting cabotegravir plus rilpivirine as direct-to-injection or with an oral lead-in in adults with HIV-1 infection: week 124 results of the open-label phase 3 FLAIR study

Autor: Orkin, Chloe ^*, Bernal Morell, Enrique, Tan, Darrell H S, Katner, Harold, Stellbrink, Hans-Jürgen, Belonosova, Elena, DeMoor, Rebecca, Griffith, Sandy, Thiagarajah, Shanker, Van Solingen-Ristea, Rodica, Ford, Susan L, Crauwels, Herta, Patel, Parul, Cutrell, Amy, Smith, Kimberly Y, Vandermeulen, Kati, Birmingham, Eileen, St Clair, Marty, Spreen, William R, D'Amico, Ronald

Publikováno v: In The Lancet HIV November 2021 8(11):e668-e678

Long-acting cabotegravir and rilpivirine dosed every 2 months in adults with HIV-1 infection (ATLAS-2M), 48-week results: a randomised, multicentre, open-label, phase 3b, non-inferiority study

Autor: Overton, Edgar T ^*, Richmond, Gary, Rizzardini, Giuliano, Jaeger, Hans, Orrell, Catherine, Nagimova, Firaya, Bredeek, Fritz, García Deltoro, Miguel, Swindells, Susan, Andrade-Villanueva, Jaime Federico, Wong, Alexander, Khuong-Josses, Marie-Aude, Van Solingen-Ristea, Rodica, van Eygen, Veerle, Crauwels, Herta, Ford, Susan, Talarico, Christine, Benn, Paul, Wang, Yuanyuan, Hudson, Krischan J, Chounta, Vasiliki, Cutrell, Amy, Patel, Parul, Shaefer, Mark, Margolis, David A, Smith, Kimberly Y, Vanveggel, Simon, Spreen, William

Publikováno v: In The Lancet 19 December 2020-1 January 2021 396(10267):1994-2005

Fixed-dose combination dolutegravir, abacavir, and lamivudine versus ritonavir-boosted atazanavir plus tenofovir disoproxil fumarate and emtricitabine in previously untreated women with HIV-1 infection (ARIA): week 48 results from a randomised, open-label, non-inferiority, phase 3b study

Autor: Cahn, Pedro Enrique, Cassetti, Lidia Isabel, Porteiro Barreira, Norma, Angel, Jonathan Benjamin, de Pokomandy, Alexandra, Harris, Marianne, Rachlis, Anita R., Walmsley, Sharon L., Allavena, Clotilde, Bouchaud, Oliver, Gatey, Caroline, Rami, Agathe, Casari, Salvatore, Di Perri, Giovanni, Lazzarin, Adriano, Maggiolo, Franco, Penco, Giovanni, Quirino, Tiziana, Rizzardini, Giuliano, Andrade-Villanueva, Jaime-Federico, Sierra-Madero, Juan G., Branco, Teresa, Serrao, Rosario, Teofilo, Eugenio JR., Melendez-Rivera, Ivan, Santiago, Lizette, Zorrilla, Carmen D., Belonosova, Elena, Chernova, Oksana E., Pokrovsky, Vadim, Rakhmanova, Aza Gasanovna, Tsybakova, Olga, Voronin, Eugene, Orrell, Catherine, Vally, Tasneem, Farisani, Livhuwani ML., Sebopa, Boitumelo Lucrecia, Barros, Carlos Aguado, Cano Sánchez, Alfredo, Castaño, Manuel, Falcó Ferrer, Vicens, González García, Juan J., Hernandez-Quero, Jose, Negredo Puigmal, Eugenia, Pérez Elías, María Jesús, Podzamczer Palter, Daniel, Portilla, Joaquin Sogorb, Viciana Fernández, Pompeyo, Manosuthi, Weerawat, Ruxrungtham, Kiat, Dockrell, David H., Hay, Phillip E., Johnson, Margaret A., Mackie, Nicola E., Orkin, Chloe M., Taylor, Steve, Bhatti, Laveeza, Brar, Indira, Brennan, Robert Owen, Cade, Jerry L., Casanas, Beata, Casey, Kathleen, Cunningham, Douglas, DeJesus, Edwin, Dietz, Craig, Dretler, Robin Henry, Eron, Joseph J., Jr., Felizarta, Franco Antoni B., Fife, Kenneth H., Hagins, Debbie P., Hoffman-Terry, Margaret, Jain, Mamta, Johnson, Marc Alexander, Kinder, Clifford A., Kumar, Princy N., Lewis, Stanley T., Jr., McDonald, Cheryl Kay, Meza, Armando D., Mounzer, Karam C., Newman, Cheryl L., Osiyemi, Olayemi O., Poblete, Ronald, Presti, Rachel M., Ramgopal, Moti, Rosenstock, Joel, Samuel, Rafik, Sandkovsky, Uriel Sebastian, Shon, Alyssa So Young, Skiest, Daniel J., Sloan, Louis M., Small, Catherine B., Tebas, Pablo, Van Dam, Cornelius N., Hagins, Debbie P, Porteiro, Norma, Walmsley, Sharon, Falcó, Vicenç, Man, Choy Y, Aylott, Alicia, Buchanan, Ann M, Wynne, Brian, Vavro, Cindy, Aboud, Michael, Smith, Kimberly Y

Publikováno v: In The Lancet HIV December 2017 4(12):e536-e546

Safety and tolerability of long-acting cabotegravir injections in HIV-uninfected men (ECLAIR): a multicentre, double-blind, randomised, placebo-controlled, phase 2a trial

Autor: Markowitz, Martin, Frank, Ian, Grant, Robert M, Mayer, Kenneth H, Elion, Richard, Goldstein, Deborah, Fisher, Chester, Sobieszczyk, Magdalena E, Gallant, Joel E, Van Tieu, Hong, Weinberg, Winkler, Margolis, David A, Hudson, Krischan J, Stancil, Britt S, Ford, Susan L, Patel, Parul, Gould, Elizabeth, Rinehart, Alex R, Smith, Kimberly Y, Spreen, William R

Publikováno v: In The Lancet HIV August 2017 4(8):e331-e340