Proposing a Clinical Model for RBE Based on Proton Track-End Counts.

Autor: Henthorn NT; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom; Manchester Academic Health Science Centre, The Christie NHS Foundation Trust, Manchester, United Kingdom. Electronic address: nicholas.henthorn@manchester.ac.uk., Gardner LL; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, United Kingdom., Aitkenhead AH; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom; Christie Medical Physics and Engineering, The Christie NHS Foundation Trust, Manchester, United Kingdom., Rowland BC; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom; Manchester Academic Health Science Centre, The Christie NHS Foundation Trust, Manchester, United Kingdom., Shin J; Department of Radiation Oncology, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts., Smith EAK; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom; Manchester Academic Health Science Centre, The Christie NHS Foundation Trust, Manchester, United Kingdom., Merchant MJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom; Manchester Academic Health Science Centre, The Christie NHS Foundation Trust, Manchester, United Kingdom., Mackay RI; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom; Christie Medical Physics and Engineering, The Christie NHS Foundation Trust, Manchester, United Kingdom., Kirkby KJ; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom; Manchester Academic Health Science Centre, The Christie NHS Foundation Trust, Manchester, United Kingdom., Chaudhary P; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, United Kingdom., Prise KM; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, United Kingdom., McMahon SJ; Patrick G. Johnston Centre for Cancer Research, Queen's University Belfast, Belfast, United Kingdom., Underwood TSA; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom; Manchester Academic Health Science Centre, The Christie NHS Foundation Trust, Manchester, United Kingdom; Leo Cancer Care Ltd, Unit 1 Woodbridge House, Chapel Rd, Smallfield, Horley RH6 9NW, United Kingdom.

Publikováno v: International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2023 Jul 15; Vol. 116 (4), pp. 916-926. Date of Electronic Publication: 2023 Jan 13.

In Silico Models of DNA Damage and Repair in Proton Treatment Planning: A Proof of Concept.

Autor: Smith EAK; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK. edward.smith-4@postgrad.manchester.ac.uk.; Christie Medical Physics and Engineering, The Christie NHS Foundation Trust, Manchester, UK. edward.smith-4@postgrad.manchester.ac.uk., Henthorn NT; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Warmenhoven JW; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Ingram SP; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Christie Medical Physics and Engineering, The Christie NHS Foundation Trust, Manchester, UK., Aitkenhead AH; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Christie Medical Physics and Engineering, The Christie NHS Foundation Trust, Manchester, UK., Richardson JC; Christie Medical Physics and Engineering, The Christie NHS Foundation Trust, Manchester, UK., Sitch P; Christie Medical Physics and Engineering, The Christie NHS Foundation Trust, Manchester, UK., Chadwick AL; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Underwood TSA; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Merchant MJ; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Burnet NG; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Kirkby NF; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Kirkby KJ; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK., Mackay RI; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.; Christie Medical Physics and Engineering, The Christie NHS Foundation Trust, Manchester, UK.

Publikováno v: Scientific reports [Sci Rep] 2019 Dec 27; Vol. 9 (1), pp. 19870. Date of Electronic Publication: 2019 Dec 27.

Clinically relevant nanodosimetric simulation of DNA damage complexity from photons and protons.

Autor: Henthorn NT; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester UK nicholas.henthorn@manchester.ac.uk.; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre Manchester UK., Warmenhoven JW; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester UK nicholas.henthorn@manchester.ac.uk.; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre Manchester UK., Sotiropoulos M; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester UK nicholas.henthorn@manchester.ac.uk., Aitkenhead AH; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester UK nicholas.henthorn@manchester.ac.uk.; Christie Medical Physics and Engineering, The Christie NHS Foundation Trust Manchester UK., Smith EAK; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester UK nicholas.henthorn@manchester.ac.uk.; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre Manchester UK., Ingram SP; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester UK nicholas.henthorn@manchester.ac.uk.; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre Manchester UK., Kirkby NF; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester UK nicholas.henthorn@manchester.ac.uk.; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre Manchester UK., Chadwick AL; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester UK nicholas.henthorn@manchester.ac.uk.; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre Manchester UK., Burnet NG; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester UK nicholas.henthorn@manchester.ac.uk.; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre Manchester UK., Mackay RI; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester UK nicholas.henthorn@manchester.ac.uk.; Christie Medical Physics and Engineering, The Christie NHS Foundation Trust Manchester UK., Kirkby KJ; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester UK nicholas.henthorn@manchester.ac.uk.; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre Manchester UK., Merchant MJ; Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, The University of Manchester UK nicholas.henthorn@manchester.ac.uk.; The Christie NHS Foundation Trust, Manchester Academic Health Science Centre Manchester UK.

Publikováno v: RSC advances [RSC Adv] 2019 Feb 28; Vol. 9 (12), pp. 6845-6858. Date of Electronic Publication: 2019 Feb 28 (Print Publication: 2019).