Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Smith Colin William"'
Autor:
Kelly A. Halliday, Smith Colin William, Rosemarie Tomlinson, W. Martin Owton, Michael Brunavs, David R. Dobson, Stephen L. Carney, Miles Martin Victor, Richard J. Broadmore, Samantha J. Ambler, Ann E. Kingston, David J. Steggles, Peter Thaddeus Gallagher, T. A. Hicks
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:817-822
Rhein has been shown to inhibit the uptake of glucose into Ehrlich Ascites tumor cells. In this paper we show that a wide range of antrhaquinones related to rhein can also inhibit glucose uptake into chondrocytes, many significantly more than the par
Autor:
Graham N. Wishart, James M. Bailey, Caroline A Hicks, Smith Colin William, Anita K. Harvey, Michael E.J. Billingham, Ann E. Kingston, Srinivasan Chandrasekhar, Dell Colin Peter
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 5:2783-2788
A new series of naphtho[1,2-b]pyran-3-carbonitriles with enhanced stability under acid conditions has been synthesised and examined for antiproliferative and anti-inflammatory activity. 4-(3-nitrophenyl)-2-(N-succinimido)-4H-naphtho[1,2-b]pyran-3-car
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 4:1673-1678
5-Amino-3-substituted-1,2,4-thiadiazoles have been found to reduce the inflammatory and arthritic symptoms in the adjuvant arthritis model of rheumatoid arthritis.
Publikováno v:
Tetrahedron Letters. 34:7447-7450
Islandicin, a mould metabolite, can be synthesised in a few, robust, high yielding steps. This procedure can be further elaborated to give a variety of hydroxy-9,10-anthraquinone-2-carboxylic acids.
Publikováno v:
ChemInform. 22
Publikováno v:
ChemInform. 25
The reaction of 4-fluoro-3-nitrobenzylidene malononitrile (3) with piperidine and 1-naphthol yields the addition-elimination product (9) rather than the expected naphtho[1,2-b]pyran (7). This reaction is extended to produce other 3,4-disubstituted be
Publikováno v:
ChemInform. 25
Islandicin, a mould metabolite, can be synthesised in a few, robust, high yielding steps. This procedure can be further elaborated to give a variety of hydroxy-9,10-anthraquinone-2-carboxylic acids.
Publikováno v:
ChemInform. 26
Autor:
Graham N. Wishart, M. E. J. Billingham, Dell Colin Peter, Srinivasan Chandrasekhar, J. M. Bailey, Smith Colin William, Ann E. Kingston, Caroline A Hicks, Anita K. Harvey
Publikováno v:
ChemInform. 27
Autor:
Nicolas Dreyfus, Adam J. Sanderson, Dell Colin Peter, Frederic L. Cordier, Veronique Dehlinger, Smith Colin William, Nikki Jenkins
Publikováno v:
ChemInform. 38
An efficient methodology for the synthesis of complex pyridin-3-yl-phenyl biaryl systems is described; microwave irradiation greatly enhances the rate of the two Pd-catalyzed key steps: formation of the stannane partner and its subsequent Stille coup