The successes and challenges of harmonising juvenile idiopathic arthritis (JIA) datasets to create a large-scale JIA data resource.

Autor: Lawson-Tovey, Saskia^1,2 (AUTHOR) saskia.lawson-tovey@manchester.ac.uk, Smith, Samantha Louise¹ (AUTHOR), Geifman, Nophar³ (AUTHOR), Shoop-Worrall, Stephanie^4,5 (AUTHOR), Ng, Sandra⁶ (AUTHOR), Barnes, Michael R.⁶ (AUTHOR), Wedderburn, Lucy R.^7,8 (AUTHOR), Hyrich, Kimme L.^2,4 (AUTHOR), CLUSTER consortium (AUTHOR), Kartawinata, Melissa (AUTHOR), Wanstall, Zoe (AUTHOR), Jebson, Bethany R. (AUTHOR), McNeece, Alyssia (AUTHOR), Ralph, Elizabeth (AUTHOR), Alexiou, Vasiliki (AUTHOR), Dekaj, Fatjon (AUTHOR), Kimonyo, Aline (AUTHOR), Merali, Fatema (AUTHOR), Sumner, Emma (AUTHOR), Robinson, Emily (AUTHOR)

Publikováno v: Pediatric Rheumatology. 7/13/2023, Vol. 21 Issue 1, p1-10. 10p.

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Previously reported PDE3A-SLCO1C1 genetic variant does not correlate with anti-TNF response in large UK rheumatoid arthritis cohort

Autor: Smith, Samantha Louise, Plant, Darren, Lee, Xiu Hue, Massey, Jonathan, Hyrich, Kimme, Morgan, Ann W, Wilson, Anthony G, Isaacs, John, Barton, Anne

Publikováno v: Smith, S L, Plant, D, Lee, X H, Massey, J, Hyrich, K, Morgan, A W, Wilson, A G, Isaacs, J & Barton, A 2016, ' Previously reported PDE3A-SLCO1C1 genetic variant does not correlate with anti-TNF response in large UK rheumatoid arthritis cohort. ', Pharmacogenomics, vol. 17, no. 7, pp. 715-20 . https://doi.org/10.2217/pgs.16.16

Aim: A genetic variant has recently reached genome-wide significance for association with TNF-inhibitor response in rheumatoid arthritis patients. Here we undertake a replication study in a UK Caucasian population to test for association with TNF-inh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3818::e39d12c88dc25112eb17142b7d729fd8
https://www.research.manchester.ac.uk/portal/en/publications/previously-reported-pde3aslco1c1-genetic-variant-does-not-correlate-with-antitnf-response-in-large-uk-rheumatoid-arthritis-cohort(09d1e455-c78b-4e3a-9a46-f0800945b200).html

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