Zobrazeno 1 - 10
of 1 704
pro vyhledávání: '"Smith, GL"'
Autor:
De B, Ng SP, Liu AY, Avila S, Tao R, Holliday EB, Brownlee Z, Kaseb A, Lee S, Raghav K, Vauthey JN, Minsky BD, Herman JM, Das P, Smith GL, Taniguchi CM, Krishnan S, Crane CH, Grassberger C, Hong TS, Lin SH, Koong AC, Mohan R, Koay EJ
Publikováno v:
Journal of Hepatocellular Carcinoma, Vol Volume 8, Pp 57-69 (2021)
Brian De,1,* Sweet Ping Ng,1,2,* Amy Y Liu,1 Santiago Avila,1 Randa Tao,3 Emma B Holliday,1 Zachary Brownlee,4 Ahmed Kaseb,5 Sunyoung Lee,3 Kanwal Raghav,5 Jean-Nicolas Vauthey,6 Bruce D Minsky,1 Joseph M Herman,1 Prajnan Das,1 Grace L Smith,1 Cullen
Externí odkaz:
https://doaj.org/article/79f03d0d0dd74cde954386e4877b022a
Human tripartite motif protein 5a (TRIM5α) is a well-characterised restriction factor for some RNA viruses including HIV, but against DNA viruses reports are limited. Here, we demonstrate TRIM5α also restricts orthopoxviruses and, via its SPRY doma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::892699216c1e6485069a3f6999637b0d
https://ora.ox.ac.uk/objects/uuid:6ce96cf4-296b-4753-b744-06ffd5aee80e
https://ora.ox.ac.uk/objects/uuid:6ce96cf4-296b-4753-b744-06ffd5aee80e
Publikováno v:
Clinics in Medicine. 4:16-21
Background: The coronavirus disease-19 (COVID-19) pandemic is attributable to the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The pathogenesis of SARS-CoV-2 is attributed to the activation of multiple inflammatory pathways secondary
Autor:
Landi MT, Bishop DT, MacGregor S, Machiela MJ, Stratigos AJ, Ghiorzo P, Brossard M, Calista D, Choi J, Fargnoli MC, Zhang T, Rodolfo M, Trower AJ, Menin C, Martinez J, Hadjisavvas A, Song L, Stefanaki I, Scolyer R, Yang R, Goldstein AM, Potrony M, Kypreou KP, Pastorino L, Queirolo P, Pellegrini C, Cattaneo L, Zawistowski M, Gimenez-Xavier P, Rodriguez A, Elefanti L, Manoukian S, Rivoltini L, Smith BH, Loizidou MA, Del Regno L, Massi D, Mandala M, Khosrotehrani K, Akslen LA, Amos CI, Andresen PA, Avril MF, Azizi E, Soyer HP, Bataille V, Dalmasso B, Bowdler LM, Burdon KP, Chen WV, Codd V, Craig JE, Debniak T, Falchi M, Fang S, Friedman E, Simi S, Galan P, Garcia-Casado Z, Gillanders EM, Gordon S, Green A, Gruis NA, Hansson J, Harland M, Harris J, Helsing P, Henders A, Hocevar M, Höiom V, Hunter D, Ingvar C, Kumar R, Lang J, Lathrop GM, Lee JE, Li X, Lubinski J, Mackie RM, Malt M, Malvehy J, McAloney K, Mohamdi H, Molven A, Moses EK, Neale RE, Novakovic S, Nyholt DR, Olsson H, Orr N, Fritsche LG, Puig-Butille JA, Qureshi AA, Radford-Smith GL, Randerson-Moor J, Requena C, Rowe C, Samani NJ, Sanna M, Schadendorf D, Schulze HJ, Simms LA, Smithers M, Song F, Swerdlow AJ, van der Stoep N, Kukutsch NA, Visconti A, Wallace L, Ward SV, Wheeler L, Sturm RA, Hutchinson A, Jones K, Malasky M, Vogt A, Zhou W, Pooley KA, Elder DE, Han J, Hicks B, Hayward NK, Kanetsky PA, Brummett C, Montgomery GW, Olsen CM, Hayward C, Dunning AM, Martin NG, Evangelou E, Mann GJ, Long G, Pharoah PDP, Easton DF, Barrett JH, Cust AE, Abecasis G, Duffy DL, Whiteman DC, Gogas H, De Nicolo A, Tucker MA, Newton-Bishop JA, GenoMEL Consortium, Q-MEGA and QTWIN Investigators, ATHENS Melanoma Study Group, 23andMe, SDH Study Group, IBD Investigators, Essen-Heidelberg Investigators, AMFS Investigators, MelaNostrum Consortium, Peris K, Chanock SJ, Demenais F, Brown KM, Puig S, Nagore E, Shi J, Iles MM, Law MH
Publikováno v:
NATURE GENETICS
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-FISABIO. Repositorio Institucional de Producción Científica
instname
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Meta-analysis of 36,760 cases and 375,188 controls identifies 54 loci associated with susceptibility to cutaneous melanoma. Further analysis combining nevus count and hair color GWAS results provide insights into the genetic architecture of melanoma.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::49ffdffa88c2703a078a866f66e1098f
http://hdl.handle.net/11391/1480983
http://hdl.handle.net/11391/1480983
Autor:
Duffy, David L, Zhu, Gu, Xin, Li, Sanna, Marianna, Iles, Mark M, Jacobs, Leonie C, Evans, David M, Yazar, Seyhan, Beesley, Jonathan, Law, Matthew H, Kraft, Peter, Visconti, Alessia, Taylor, John C, Lui, Fan, Wright, Margaret J, Henders, Anjali K, Bowdler, Lisa, Glass, Dan, Ikram, Arfan M, Uitterlinden, André G, Madden, Pamela A, Heath, Andrew C, Nelson, Elliot C, Green, Adele C, Chanock, Stephen, Barrett, Jennifer H, Brown, Matthew A, Hayward, Nicholas K, Macgregor, Stuart, Sturm, Richard A, Hewitt, Alex W, Kayser, Manfred, Hunter, David J, Newton Bishop, Julia A, Spector, Timothy D, Montgomery, Grant W, Mackey, David A, Smith, George Davey, Nijsten, Tamar E, Bishop, D Timothy, Bataille, Veronique, Falchi, Mario, Han, Jiali, Martin, Nicholas, G, Lee, Je, Brossard, M, Moses, Ek, Song, F, Kumar, R, Easton, Df, Pharoah, Pdp, Swerdlow, Aj, Kypreou, Kp, Harland, M, Randerson-Moor, J, Akslen, La, Andresen, Pa, Avril, Mf, Azizi, E, Scarrà, Gb, Brown, Km, Dębniak, T, Elder, De, Fang, S, Friedman, E, Galan, P, Ghiorzo, P, Gillanders, Em, Goldstein, Am, Gruis, Na, Hansson, J, Helsing, P, Hočevar, M, Höiom, V, Ingvar, C, Kanetsky, Pa, Chen, Wv, Landi, Mt, Lang, J, Lathrop, Gm, Lubiński, J, Mackie, Rm, Mann, Gj, Molven, A, Novaković, S, Olsson, H, Puig, S, Puig-Butille, Ja, Radford-Smith, Gl, van der Stoep, N, van Doorn, R, Whiteman, Dc, Craig, Je, Schadendorf, D, Simms, La, Burdon, Kp, Nyholt, Dr, Pooley, Ka, Orr, N, Stratigos, Aj, Cust, Ae, Ward, Sv, Schulze, Hj, Dunning, Am, Demenais, F, Amos, Ci.
Publikováno v:
Nature Communications, 9:4774. Nature Publishing Group
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Duffy, D L, Zhu, G, Li, X, Sanna, M, Iles, M M, Jacobs, L C, Evans, D M, Yazar, S, Beesley, J, Law, M H, Kraft, P, Visconti, A, Taylor, J C, Lui, F, Henders, A K, Bowdler, L, Glass, D, Ikram, A M, Uitterlinden, A G, Wright, M J, Madden, P A, Heath, A C, Nelson, E C, Green, A C, Chanock, S, Barrett, J H, Brown, M A, Hayward, N K, MacGregor, S, Sturm, R A, Hewitt, A W, Kayser, M, Hunter, D J, Newton Bishop, J A, Spector, T D, Montgomery, G W, Mackey, D A, Smith, G D, Nijsten, T E, Bishop, D T, Bataille, V, Falchi, M & Han, J & Martin, N G 2018, ' Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways ', Nature Communications, vol. 9, no. 1, pp. 4774 . https://doi.org/10.1038/s41467-018-06649-5
Melanoma GWAS Consortium 2018, ' Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways ', Nature Communications, vol. 9, no. 1, 4774 . https://doi.org/10.1038/s41467-018-06649-5
Duffy, D L, Zhu, G, Li, X, Sanna, M, Iles, M M, Jacobs, L C, Evans, D M, Yazar, S, Beesley, J, Law, M H, Kraft, P, Visconti, A, Taylor, J C, Lui, F, Wright, M J, Henders, A K, Bowdler, L, Glass, D, Ikram, A M, Uitterlinden, A G, Madden, P A, Heath, A C, Nelson, E C, Green, A C, Chanock, S, Barrett, J H, Brown, M A, Hayward, N K, MacGregor, S, Sturm, R A, Hewitt, A W, Lee, J E, Brossard, M, Moses, E K, Song, F, Kumar, R, Easton, D F, Pharoah, P D P, Swerdlow, A J, Kypreou, K P, Harland, M, Randerson-Moor, J, Akslen, L A, Andresen, P A, Avril, M F, Azizi, E, Scarrà, G B, Brown, K M & Dębniak, T & Smith, G D 2018, ' Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways ', Nature Communications, vol. 9, 4774 . https://doi.org/10.1038/s41467-018-06649-5
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Duffy, D L, Zhu, G, Li, X, Sanna, M, Iles, M M, Jacobs, L C, Evans, D M, Yazar, S, Beesley, J, Law, M H, Kraft, P, Visconti, A, Taylor, J C, Lui, F, Henders, A K, Bowdler, L, Glass, D, Ikram, A M, Uitterlinden, A G, Wright, M J, Madden, P A, Heath, A C, Nelson, E C, Green, A C, Chanock, S, Barrett, J H, Brown, M A, Hayward, N K, MacGregor, S, Sturm, R A, Hewitt, A W, Kayser, M, Hunter, D J, Newton Bishop, J A, Spector, T D, Montgomery, G W, Mackey, D A, Smith, G D, Nijsten, T E, Bishop, D T, Bataille, V, Falchi, M & Han, J & Martin, N G 2018, ' Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways ', Nature Communications, vol. 9, no. 1, pp. 4774 . https://doi.org/10.1038/s41467-018-06649-5
Melanoma GWAS Consortium 2018, ' Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways ', Nature Communications, vol. 9, no. 1, 4774 . https://doi.org/10.1038/s41467-018-06649-5
Duffy, D L, Zhu, G, Li, X, Sanna, M, Iles, M M, Jacobs, L C, Evans, D M, Yazar, S, Beesley, J, Law, M H, Kraft, P, Visconti, A, Taylor, J C, Lui, F, Wright, M J, Henders, A K, Bowdler, L, Glass, D, Ikram, A M, Uitterlinden, A G, Madden, P A, Heath, A C, Nelson, E C, Green, A C, Chanock, S, Barrett, J H, Brown, M A, Hayward, N K, MacGregor, S, Sturm, R A, Hewitt, A W, Lee, J E, Brossard, M, Moses, E K, Song, F, Kumar, R, Easton, D F, Pharoah, P D P, Swerdlow, A J, Kypreou, K P, Harland, M, Randerson-Moor, J, Akslen, L A, Andresen, P A, Avril, M F, Azizi, E, Scarrà, G B, Brown, K M & Dębniak, T & Smith, G D 2018, ' Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways ', Nature Communications, vol. 9, 4774 . https://doi.org/10.1038/s41467-018-06649-5
The total number of acquired melanocytic nevi on the skin is strongly correlated with melanoma risk. Here we report a meta-analysis of 11 nevus GWAS from Australia, Netherlands, United Kingdom, and United States, comprising a total of 52,506 phenotyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fdc17d2ba531806731975db2a684a16
https://www.repository.cam.ac.uk/handle/1810/288608
https://www.repository.cam.ac.uk/handle/1810/288608
Autor:
Zhang, Tongwu, Choi, Jiyeon, Kovacs, Michael A., Shi, Jianxin, Mai, Xu, Goldstein, Alisa M., Trower, Adam J., Bishop, D. Timothy, Iles, Mark M., Duffy, David L., Macgregor, Stuart, Amundadottir, Laufey T., Law, Matthew H., Loftus, Stacie K., Pavan, William J., Brown, Kevin M., Lee, Je, Brossard, M, Martin, Ng, Moses, Ek, Song, F, Barrett, Jh, Kumar, R, Easton, Df, Pharoah, Pdp, Swerdlow, Aj, Kypreou, Kp, Taylor, Jc, Harland, M, Randerson-Moor, J, Akslen, La, Andresen, Pa, Avril, Mf, Azizi, E, Bianchi Scarrà, G, Dȩbniak, T, Duffy, Dl, Elder, De, Fang, S, Friedman, E, Galan, P, Ghiorzo, P, Gillanders, Em, Goldstein, Am, Gruis, Na, Hansson, J, Helsing, P, Hočevar, M, Höiom, V, Ingvar, C, Kanetsky, Pa, Chen, Wv, Landi, Mt, Lang, J, Lathrop, Gm, Lubiński, J, Mackie, Rm, Mann, Gj, Molven, A, Montgomery, Gw, Novaković, S, Olsson, H, Puig, S, Puig-Butille, Ja, Wu, W, Qureshi, Aa, Radford-Smith, Gl, van der Stoep, N, van Doorn, R, Whiteman, Dc, Craig, Je, Schadendorf, D, Simms, La, Burdon, Kp, Nyholt, Dr, Pooley, Ka, Orr, N, Stratigos, Aj, Cust, Ae, Ward, Sv, Hayward, Nk, Han, J, Schulze, Hj, Dunning, Am, Bishop, Jan, Demenais, F, Amos, Ci, Macgregor, S, Iles, Mm, Barnabas, Bb, Bouffard, Gg, Brooks, Sy, Coleman, H, Dekhtyar, L, Guan, X, Ho, Sl, Legaspi, R, Maduro, Ql, Masiello, Ca, Mcdowell, Jc, Montemayor, C, Mullikin, Jc, Park, M, Riebow, Nl, Schandler, K, Schmidt, B, Sison, C, Smith, R, Stantripop, S, Thomas, Jw, Thomas, Pj, Vemulapalli, M, Young, Ac.
Publikováno v:
Genome Research, 28(11), 1621-1635
Most expression quantitative trait locus (eQTL) studies to date have been performed in heterogeneous tissues as opposed to specific cell types. To better understand the cell-type–specific regulatory landscape of human melanocytes, which give rise t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f62743de9139d3fa5865ac39a0f335
https://europepmc.org/articles/PMC6211648/
https://europepmc.org/articles/PMC6211648/
Autor:
Bolotov, VA, Kovalenko, KA, Samsonenko, DG, Han, X, Zhang, X, Smith, GL, McCormick, LJ, Teat, SJ, Yang, S, Lennox, MJ, Henley, A, Besley, E, Fedin, VP, Dybtsev, DN, Schröder, M
Publikováno v:
Bolotov, VA; Kovalenko, KA; Samsonenko, DG; Han, X; Zhang, X; Smith, GL; et al.(2018). Enhancement of CO2Uptake and Selectivity in a Metal-Organic Framework by the Incorporation of Thiophene Functionality. Inorganic Chemistry, 57(9), 5074-5082. doi: 10.1021/acs.inorgchem.8b00138. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/2f60x4h6
© 2018 American Chemical Society. The complex [Zn2(tdc)2dabco] (H2tdc = thiophene-2,5-dicarboxylic acid; dabco = 1,4-diazabicyclooctane) shows a remarkable increase in carbon dioxide (CO2) uptake and CO2/dinitrogen (N2) selectivity compared to the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::2a77cc2703e81996aa2af774d1a1cfe1
http://www.escholarship.org/uc/item/2f60x4h6
http://www.escholarship.org/uc/item/2f60x4h6
Vaccinia virus produces two distinct infectious virions; the single-enveloped intracellular mature virus (IMV), which remains in the cell until cell lysis, and the double-enveloped extracellular enveloped virus (EEV), which mediates virus spread. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______109::92dc4074f83498697686333eef10180d
https://www.repository.cam.ac.uk/handle/1810/267720
https://www.repository.cam.ac.uk/handle/1810/267720
Human cytotoxic T cells specific for influenza A virus were tested for recognition of each of the ten influenza A virus proteins expressed in target cells using recombinant vaccinia viruses. They recognized the matrix M1, polymerase PB2, and nucleopr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2dfd2868b1fb060d832c56fd0f58f41
Vaccinia virus (VACV) utilizes microtubule-mediated trafficking at several stages of its life cycle, of which virus egress is the most intensely studied. During egress VACV proteins A36, F12 and E2 are involved in kinesin-1 interactions; however, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______109::1ee718bf141f4988aebc8e6acf0d1d01
https://www.repository.cam.ac.uk/handle/1810/265934
https://www.repository.cam.ac.uk/handle/1810/265934