Negative modulation of AMPA receptors bound to transmembrane AMPA receptor regulatory protein γ-8 blunts the positive reinforcing properties of alcohol and sucrose in a brain region-dependent manner in male mice.

Autor: Hoffman, Jessica L., Faccidomo, Sara P., Taylor, Seth M., DeMiceli, Kristina G., May, Ashley M., Smith, Evan N., Whindleton, Ciarra M., Hodge, Clyde W.

Publikováno v: Psychopharmacology; Jun2023, Vol. 240 Issue 6, p1261-1273, 13p, 1 Diagram, 3 Graphs

Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease.

Autor: Hoffman JL; Department of Psychiatry, Center for Alcohol Studies, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., Faccidomo S; Department of Psychiatry, Center for Alcohol Studies, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., Kim M; Department of Psychiatry, Center for Alcohol Studies, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., Taylor SM; Department of Psychiatry, Center for Alcohol Studies, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., Agoglia AE; Department of Psychiatry, Center for Alcohol Studies, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., May AM; Department of Psychiatry, Center for Alcohol Studies, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., Smith EN; Department of Psychiatry, Center for Alcohol Studies, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., Wong LC; Department of Psychiatry, Center for Alcohol Studies, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States., Hodge CW; Department of Psychiatry, Center for Alcohol Studies, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States. Electronic address: chodge@med.unc.edu.

Publikováno v: International review of neurobiology [Int Rev Neurobiol] 2019; Vol. 148, pp. 169-230. Date of Electronic Publication: 2019 Oct 23.