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Damage-induced pyroptosis drives endog thymic regeneration via induction of Foxn1 by purinergic receptor activation.

Autor: Kinsella S; Program in Immunology, Division of Translational Science and Therapeutics, Fred Hutchinson Cancer Center, Seattle WA, 98109, US.; Immunotherapy Integrated Research Center, Fred Hutchinson Cancer Research Center, Seattle WA, 98109, US., Evandy CA; Program in Immunology, Division of Translational Science and Therapeutics, Fred Hutchinson Cancer Center, Seattle WA, 98109, US.; Immunotherapy Integrated Research Center, Fred Hutchinson Cancer Research Center, Seattle WA, 98109, US., Cooper K; Program in Immunology, Division of Translational Science and Therapeutics, Fred Hutchinson Cancer Center, Seattle WA, 98109, US.; Immunotherapy Integrated Research Center, Fred Hutchinson Cancer Research Center, Seattle WA, 98109, US., Cardinale A; Department of Pediatric Hematology and Oncology, Bambino Gesù Children's Hospital, IRCCS, Rome, 00146, Italy., Iovino L; Program in Immunology, Division of Translational Science and Therapeutics, Fred Hutchinson Cancer Center, Seattle WA, 98109, US.; Immunotherapy Integrated Research Center, Fred Hutchinson Cancer Research Center, Seattle WA, 98109, US., deRoos P; Program in Immunology, Division of Translational Science and Therapeutics, Fred Hutchinson Cancer Center, Seattle WA, 98109, US.; Immunotherapy Integrated Research Center, Fred Hutchinson Cancer Research Center, Seattle WA, 98109, US., Hopwo KS; Program in Immunology, Division of Translational Science and Therapeutics, Fred Hutchinson Cancer Center, Seattle WA, 98109, US.; Immunotherapy Integrated Research Center, Fred Hutchinson Cancer Research Center, Seattle WA, 98109, US., Smith CW; Program in Immunology, Division of Translational Science and Therapeutics, Fred Hutchinson Cancer Center, Seattle WA, 98109, US.; Immunotherapy Integrated Research Center, Fred Hutchinson Cancer Research Center, Seattle WA, 98109, US., Granadier D; Program in Immunology, Division of Translational Science and Therapeutics, Fred Hutchinson Cancer Center, Seattle WA, 98109, US.; Immunotherapy Integrated Research Center, Fred Hutchinson Cancer Research Center, Seattle WA, 98109, US.; Medical Scientist Training Program, University of Washington, Seattle WA, 98195, US., Sullivan LB; Human Biology Division, Fred Hutchinson Cancer Center, Seattle WA, 98109, US., Velardi E; Department of Pediatric Hematology and Oncology, Bambino Gesù Children's Hospital, IRCCS, Rome, 00146, Italy., Dudakov JA; Program in Immunology, Division of Translational Science and Therapeutics, Fred Hutchinson Cancer Center, Seattle WA, 98109, US.; Immunotherapy Integrated Research Center, Fred Hutchinson Cancer Research Center, Seattle WA, 98109, US.; Department of Immunology, University of Washington, Seattle WA, 98195, US.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jan 20. Date of Electronic Publication: 2023 Jan 20.