Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Smith, Christopher Wj"'
Autor:
Llorian, Miriam, Smith, Christopher WJ
Publikováno v:
In Current Opinion in Genetics & Development 2011 21(4):380-387
The maturation of immature B cells and the survival of mature B cells is stringently controlled to maintain a diverse repertoire of antibody specificities while avoiding self-reactivity. At the molecular level this is regulated by signaling from memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2977bbb65e3f23da3e73fff3819261
https://www.repository.cam.ac.uk/handle/1810/325258
https://www.repository.cam.ac.uk/handle/1810/325258
Autor:
McGlincy, Nicholas J, Lit-Yeen Tan, Nicodeme Paul, Zavolan, Mihaela, Lilley, Kathryn S, Smith, Christopher WJ
Additional file 3: A. Novel 3' UTR sequence of HNRNPA2B1 constructed from RACE tags. Exon sequence is capitalised. HNRNPA1 and A2/B1 motifs from [91] are emboldened and underlined. The small UTR intron present in the Refseq UTR is outlined in black.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e74d8d5be870df15427821ee35a175
Autor:
McGlincy, Nicholas J, Lit-Yeen Tan, Nicodeme Paul, Zavolan, Mihaela, Lilley, Kathryn S, Smith, Christopher WJ
Additional file of Expression proteomics of UPF1 knockdown in HeLa cells reveals autoregulation of hnRNP A2/B1 mediated by alternative splicing resulting in nonsense-mediated mRNA decay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4c72814cd1348e062dcb8d48fa287ff
Autor:
Zavolan Mihaela, Paul Nicodeme, Tan Lit-Yeen, McGlincy Nicholas J, Lilley Kathryn S, Smith Christopher WJ
Publikováno v:
BMC Genomics, Vol 11, Iss 1, p 565 (2010)
Abstract Background In addition to acting as an RNA quality control pathway, nonsense-mediated mRNA decay (NMD) plays roles in regulating normal gene expression. In particular, the extent to which alternative splicing is coupled to NMD and the roles
Externí odkaz:
https://doaj.org/article/3715f933e05e44918204b2e0cf70207d
Autor:
Tan, Lit-Yeen, Whitfield, Peter, Llorian, Miriam, Monzon-Casanova, Elisa, Diaz-Munoz, Manuel D, Turner, Martin, Smith, Christopher WJ
Publikováno v:
Nucleic Acids Research
Polypyrimidine tract binding protein (PTBP1) is a widely expressed RNA binding protein that acts as a regulator of alternative splicing and of cytoplasmic mRNA functions. Vertebrates contain two closely-related paralogs with >75% amino acid sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6fe2ace0c874735cfbadd875d8e30600
http://europepmc.org/articles/PMC4477659
http://europepmc.org/articles/PMC4477659
Autor:
Dang Do, Vinh, Strauss, Bernhard, Cukuroglu, Engin, Macaulay, Iain, Boon Wee, Keng, Xiamoming, Tim, Ruiz De Los Mozos, Igor, Lee, Caroline, Harrison, Andrew, Butler, Richard, Dietmann, Sabine, Jernej, Ule, Marioni, John, Smith, Christopher WJ, Goke, Jonathan, Surani, Azim M
Publikováno v:
Cell Discovery, Vol 4, Iss 1, Pp 1-16 (2018)
The RNA-binding protein SRSF3 (also known as SRp20) has critical roles in the regulation of pre-mRNA splicing. Zygotic knockout of Srsf3 results in embryo arrest at the blastocyst stage. However, SRSF3 is also present in oocytes, suggesting that it m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbbb1cf454f0cb730e9932a99cd36e22
https://pubmed.ncbi.nlm.nih.gov/29928511
https://pubmed.ncbi.nlm.nih.gov/29928511
Dissecting domains necessary for activation and repression of splicing by muscleblind-like protein 1
Publikováno v:
BMC Molecular Biology
Background Alternative splicing contributes to the diversity of the proteome, and provides the cell with an important additional layer of regulation of gene expression. Among the many RNA binding proteins that regulate alternative splicing pathways a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::93e8c3cbdd06f6c2f5c24f181c744e46
http://europepmc.org/articles/PMC3880588
http://europepmc.org/articles/PMC3880588
Autor:
Coelho, Miguel B, Attig, Jan, Bellora, Nicolás, König, Julian, Hallegger, Martina, Kayikci, Melis, Eyras, Eduardo, Ule, Jernej, Smith, Christopher WJ
Publikováno v:
EMBO Journal; Mar2015, Vol. 34 Issue 5, p653-668, 16p
Autor:
McGlincy, Nicholas J, Tan, Lit-Yeen, Paul, Nicodeme, Zavolan, Mihaela, Lilley, Kathryn S, Smith, Christopher WJ
Publikováno v:
BMC Genomics; 10/14/2010, Vol. 11 Issue 1, p1-19, 19p