Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Smita Zaheer"'
Autor:
Duraisamy Kempuraj, Shireen Mentor, Ramasamy Thangavel, Mohammad E. Ahmed, Govindhasamy Pushpavathi Selvakumar, Sudhanshu P. Raikwar, Iuliia Dubova, Smita Zaheer, Shankar S. Iyer, Asgar Zaheer
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Mast cell activation plays an important role in stress-mediated disease pathogenesis. Chronic stress cause or exacerbate aging and age-dependent neurodegenerative diseases. The severity of inflammatory diseases is worsened by the stress. Mast cell ac
Externí odkaz:
https://doaj.org/article/47a3aa91d7b045919e13565e7aaaa4ab
Autor:
Duraisamy Kempuraj, Govindhasamy P. Selvakumar, Ramasamy Thangavel, Mohammad E. Ahmed, Smita Zaheer, Sudhanshu P. Raikwar, Shankar S. Iyer, Sachin M. Bhagavan, Swathi Beladakere-Ramaswamy, Asgar Zaheer
Publikováno v:
Frontiers in Neuroscience, Vol 11 (2017)
Mast cells are localized throughout the body and mediate allergic, immune, and inflammatory reactions. They are heterogeneous, tissue-resident, long-lived, and granulated cells. Mast cells increase their numbers in specific site in the body by prolif
Externí odkaz:
https://doaj.org/article/6439ff2046784dac99bf8271e1b0a755
Autor:
Duraisamy Kempuraj, Ramasamy Thangavel, Govindhasamy P. Selvakumar, Smita Zaheer, Mohammad E. Ahmed, Sudhanshu P. Raikwar, Haris Zahoor, Daniyal Saeed, Prashant A. Natteru, Shankar Iyer, Asgar Zaheer
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Neuroinflammatory response is primarily a protective mechanism in the brain. However, excessive and chronic inflammatory responses can lead to deleterious effects involving immune cells, brain cells and signaling molecules. Neuroinflammation induces
Externí odkaz:
https://doaj.org/article/867524e3c7d14fab89a08e2f951b7e90
Autor:
Ramasamy Thangavel, Duraisamy Kempuraj, Smita Zaheer, Sudhanshu Raikwar, Mohammad E. Ahmed, Govindhasamy Pushpavathi Selvakumar, Shankar S. Iyer, Asgar Zaheer
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
Alzheimer’s disease (AD) is characterized by the presence of neuropathological lesions containing amyloid plaques (APs) and neurofibrillary tangles (NFTs). AD is associated with mitochondrial dysfunctions, neuroinflammation and neurodegeneration in
Externí odkaz:
https://doaj.org/article/34fea704b36a43dbabddd8df922bbc4a
Publikováno v:
Neurobiology of Disease, Vol 40, Iss 3, Pp 593-598 (2010)
Glia maturation factor (GMF), a primarily CNS localized protein was discovered and characterized in our laboratory. We previously demonstrated that GMF is the upstream regulator for excessive production and release of proinflammatory cytokines/chemok
Externí odkaz:
https://doaj.org/article/d07361be4e884b688078e6a6ee7d82fd
Autor:
Duraisamy Kempuraj, Ramasamy Thangavel, Evert Yang, Sagar Pattani, Smita Zaheer, Donna A Santillan, Mark K Santillan, Asgar Zaheer
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135776 (2015)
Parkinson's disease (PD) is characterized by the presence of Lewy bodies and degeneration of dopaminergic neurons. 1-methyl-4-phenylpyridinium (MPP+), a metabolite of neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and Lewy body compon
Externí odkaz:
https://doaj.org/article/922a76609170484a88d0c36737bf1606
Autor:
Govindhasamy Pushpavathi Selvakumar, Raghav Govindarajan, Shankar S. Iyer, Mohammad Ejaz Ahmed, Duraisamy Kempuraj, Sudhanshu P. Raikwar, Asgar Zaheer, Smita Zaheer, Deepak D. Kempuraj, Ramasamy Thangavel, Premkumar Nattanmai Chandrasekaran
Publikováno v:
BioFactors
Neuroinflammation leads to neurodegeneration, cognitive defects, and neurodegenerative disorders. Neurotrauma/traumatic brain injury (TBI) can cause activation of glial cells, neurons, and neuroimmune cells in the brain to release neuroinflammatory m
Autor:
Sudhanshu P. Raikwar, Ramasamy Thangavel, Kieran Bazley, Shankar S. Iyer, Casey Burton, Osaid Khan, Raghav Govindarajan, Duraisamy Kempuraj, Mohammad Ejaz Ahmed, Donald James, Smita Zaheer, Bret Bussinger, Kristopher Wu, Klaudia Kukulka, Govindhasamy Pushpavathi Selvakumar, Asgar Zaheer
Publikováno v:
Cell Mol Neurobiol
Neurotrauma especially traumatic brain injury (TBI) is the leading cause of death and disability worldwide. To improve upon the early diagnosis and develop precision-targeted therapies for TBI, it is critical to understand the underlying molecular me
Autor:
Shankar S. Iyer, Govindhasamy Pushpavathi Selvakumar, Ramasamy Thangavel, Asher Khan, Smita Zaheer, Mohammad Ejaz Ahmed, Casey Burton, Donald James, Duraisamy Kempuraj, Asgar Zaheer, Sudhanshu P. Raikwar
Publikováno v:
The Neuroscientist. 26:402-414
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new pandemic infectious disease that originated in China. COVID-19 is a global public health emergency of international concern. COVID-19
Autor:
Kieran Bazley, Govindhasamy Pushpavathi Selvakumar, Duraisamy Kempuraj, Ramasamy Thangavel, Shankar S. Iyer, Osaid Khan, Raghav Govindarajan, Casey Burton, Bret Bussinger, Iuliia Dubova, Klaudia Kukulka, Mohammad Ejaz Ahmed, Donald James, Smita Zaheer, Kristopher Wu, Asgar Zaheer, Sudhanshu P. Raikwar
Publikováno v:
Journal of Neurotrauma. 37:1645-1655
Traumatic brain injury (TBI) is the primary cause of death and disability affecting over 10 million people in the industrialized world. TBI causes a wide spectrum of secondary molecular and cellula...