Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Smita Savant-Bhonsale"'
Autor:
Xu Cui, Michael Chopp, Alex Zacharek, Cynthia Roberts, Mei Lu, Smita Savant-Bhonsale, Jieli Chen
Publikováno v:
Neurobiology of Disease, Vol 36, Iss 1, Pp 35-41 (2009)
We investigated the additive therapeutic effect of the combination treatment of stroke with sub-therapeutic doses of Simvastatin, a HMG-CoA reductase inhibitor, and bone marrow stromal cells (BMSCs). Rats were administered Simvastatin (0.5 mg/kg), BM
Externí odkaz:
https://doaj.org/article/1da9fda9355b4967b17f5d13122a86c6
Autor:
Jian Xu, Xinfeng Liu, Jieli Chen M.D., Alex Zacharek, Xu Cui, Smita Savant-Bhonsale, Michael Chopp, Zhenguo Liu M.D., PhD.
Publikováno v:
Cell Transplantation, Vol 19 (2010)
Marrow stromal cells (MSCs) are capable of differentiating into various cell types including endothelial cells. Microenvironment is important in cell fate determination. Tumor necrosis factor-α converting enzyme (TACE), a well-characterized “shedd
Externí odkaz:
https://doaj.org/article/e2d508c107fd4f8782e99d48deae8853
Autor:
Michael Chopp, Donald M. Seyfried, Jennifer Ding, Dongmei Yang, Yuxia Han, Smita Savant-Bhonsale, Li Hong Shen
Publikováno v:
Journal of Neurosurgery. 112:329-335
Object Previous studies demonstrated that intravascular injection of bone marrow stromal cells (BMSCs) significantly improved neurological functional recovery in a rat model of intracerebral hemorrhage (ICH). To further investigate the fate of transp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::044e323fa386e20bb74f443a76979d92
https://doi.org/10.3171/2009.2.jns08907
https://doi.org/10.3171/2009.2.jns08907
Autor:
Smita Savant-Bhonsale, Michael Chopp, Mei Lu, Jieli Chen, Cynthia Roberts, Alex Zacharek, Xu Cui
Publikováno v:
Neurobiology of Disease, Vol 36, Iss 1, Pp 35-41 (2009)
We investigated the additive therapeutic effect of the combination treatment of stroke with sub-therapeutic doses of Simvastatin, a HMG-CoA reductase inhibitor, and bone marrow stromal cells (BMSCs). Rats were administered Simvastatin (0.5 mg/kg), BM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e01ed3a3d0b0add756164dd5785b2eeb
https://doi.org/10.1016/j.nbd.2009.06.012
https://doi.org/10.1016/j.nbd.2009.06.012
Autor:
Mei Lu, Zheng Gang Zhang, Smita Savant-Bhonsale, Yi Li, Jade Borneman, Ben Buller, Michael Chopp, Stanton B. Elias, Jing Zhang
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 29:1166-1174
Oligodendrocytes are sensitive to ischemic damage. The Sonic hedgehog (Shh) pathway is critical in oligodendrogenesis; Gli1 is the principal effector of Shh signaling. We investigated oligodendrogenesis and Shh/Gli1 pathway activation after bone marr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3bd1cb618f94e2970c2829767c44a00
https://doi.org/10.1038/jcbfm.2009.41
https://doi.org/10.1038/jcbfm.2009.41
Autor:
Dongmei Yang, Smita Savant-Bhonsale, Mohammad S. Shukairy, Yuxia Han, Donald M. Seyfried, Michael Chopp, Jennifer Ding
Publikováno v:
Brain Research. 1224:12-19
Previous studies show that intravascular injection of human bone marrow stromal cells (hBMSCs) significantly improves neurological functional recovery in a rat model of intracerebral hemorrhage (ICH). In the present study, we tested the hypothesis th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6bd342e31cc1f8401ffefbe895d92b2
https://doi.org/10.1016/j.brainres.2008.05.080
https://doi.org/10.1016/j.brainres.2008.05.080
Autor:
Cynthia Roberts, Alex Zacharek, Jieli Chen, Smita Savant-Bhonsale, Yi Li, Xu Cui, Alissa Kapke, Michael Chopp
Publikováno v:
Stem Cells. 25:2777-2785
Stromal cell-derived factor-1 (SDF1) and its chemokine (CXC motif) receptor 4 (CXCR4), along with matrix metalloproteinases (MMPs), regulate bone marrow stromal cell (BMSC) migration. We tested the hypothesis that a nitric oxide donor, DETA-NONOate,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff15f2ead03f9c2b5456dfdc5631ca7
https://doi.org/10.1634/stemcells.2007-0169
https://doi.org/10.1634/stemcells.2007-0169
Autor:
Smita Savant-Bhonsale, Eliza Wickham Garcia, Ying Liu, Rodolfo Gonzalez, Marina Bibikova, Jian-Bing Fan, Aparna Khanna, Allan J. Robins, Thomas C. Schulz, Todd W. Plaia, Padmavathy Vanguri, Jeremy M. Crook, Dan E. Arking, Bruce Davidson, Mahendra S. Rao, Soojung Shin, Lixin Zhou, Johan Hyllner, Eugene Chudin, Aravinda Chakravarti, Peter Sartipy, Alan K. Smith, Bonnie Wu, Jonathan M. Auerbach, David L. Barker, Jeanne F. Loring, Anirban Maitra
Publikováno v:
Genome Research. 16:1075-1083
Human embryonic stem (hES) cells originate during an embryonic period of active epigenetic remodeling. DNA methylation patterns are likely to be critical for their self-renewal and pluripotence. We compared the DNA methylation status of 1536 CpG site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a009918186f6a05e71db7b3fc6d830
https://doi.org/10.1101/gr.5319906
https://doi.org/10.1101/gr.5319906
Publikováno v:
Gene. 231:155-161
Members of the RYK family of receptors are homologous to tyrosine kinases but do not exhibit kinase activity in vitro. We describe a new member of this family in Drosophila, which we call Doughnut (DNT). The protein product was found to be 70% identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6f91cc50921e4cb3930f9606d5a9f7a
https://doi.org/10.1016/s0378-1119(99)00061-x
https://doi.org/10.1016/s0378-1119(99)00061-x
Publikováno v:
Genes & Development. 7:2548-2555
Differentiation of the anterior and posterior poles of the Drosophila embryo requires seven maternally expressed genes including torso-like (tsl) and torso (tor). The tor gene encodes a receptor tyrosine kinase that is expressed throughout the embryo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18055beb99a3f36795983489317d8f98
https://doi.org/10.1101/gad.7.12b.2548
https://doi.org/10.1101/gad.7.12b.2548