Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Smita Jagtap"'
Autor:
Kesavan Meganathan, Smita Jagtap, Vilas Wagh, Johannes Winkler, John Antonydas Gaspar, Diana Hildebrand, Maria Trusch, Karola Lehmann, Jürgen Hescheler, Hartmut Schlüter, Agapios Sachinidis
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e44228 (2012)
Embryonic development can be partially recapitulated in vitro by differentiating human embryonic stem cells (hESCs). Thalidomide is a developmental toxicant in vivo and acts in a species-dependent manner. Besides its therapeutic value, thalidomide al
Externí odkaz:
https://doaj.org/article/6b00c48684334bb5a81076f377afc156
Autor:
Smita Jagtap, Kalpana Handore, Pravin Adhav, Pravin Deshpande, Abhijit Bhopale, Manisha Khaladkar, Prasad Khandagale, Vasant V. Chabukswar
Publikováno v:
Journal of Macromolecular Science, Part B. 61:942-957
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20204d243bebc5fd04cdc7f9e54d2a81
https://doi.org/10.1080/00222348.2022.2122236
https://doi.org/10.1080/00222348.2022.2122236
Autor:
Pravin Adhav, Digamber Pawar, Balasaheb Diwate, Manisha Bora, Smita Jagtap, Ashish Chourasia, Sabrina Dallavalle, Vasant Chabukswar
Publikováno v:
Synthetic Metals. 293:117237
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24042f537f9c330dc17b1dc94d2763a0
https://doi.org/10.1016/j.synthmet.2022.117237
https://doi.org/10.1016/j.synthmet.2022.117237
Autor:
Ariel Feiglin, Jennifer P. Wang, Thomas O Dial, Steven D. Sheridan, Smita Jagtap, Jeffrey Chen, Ting Fu, Jasmin Lalonde, Roy H. Perlis, Jeannie T. Lee, Isaac S. Kohane, Jessica M. Thanos
Publikováno v:
Human Molecular Genetics. 28:3625-3636
The X-linked neurodevelopmental diseases CDKL5 deficiency disorder (CDD) and Rett syndrome (RTT) are associated with intellectual disability, infantile spasms and seizures. Although mitochondrial dysfunction has been suggested in RTT, less is underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970ba92f3a14641bd30a7b886f38016c
https://doi.org/10.1093/hmg/ddz208
https://doi.org/10.1093/hmg/ddz208
Autor:
Rakesh Karmacharya, Donna L. McPhie, Kara Lopez-Lengowski, Roy H. Perlis, Bruce M. Cohen, Annie Kathuria, Smita Jagtap
Publikováno v:
JAMA Psychiatry
Importance Three-dimensional cerebral organoids generated from patient-derived induced pluripotent stem cells (iPSCs) may be used to interrogate cellular-molecular underpinnings of schizophrenia. Objective To determine transcriptomic profiles and fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1245e02bd45a3f9465e21dad73df9222
https://doi.org/10.1001/jamapsychiatry.2020.0196
https://doi.org/10.1001/jamapsychiatry.2020.0196
Autor:
Lisa Hoelting, Johannes Meisig, Christoph van Thriel, Julia Liebing, Marcel Leist, Patricio Godoy, Agapios Sachinidis, Jörg Rahnenführer, Smita Jagtap, Regina Stoeber, Sunniva Förster, Nils Bluethgen, Vaibhav Shinde, Stefan Schildknecht, Eugen Rempel, Jürgen Hescheler, Sureshkumar Perumal Srinivasan, Marianna Grinberg, Tanja Waldmann, Jan G. Hengstler, John Antonydas Gaspar, Kesavan Meganathan
Publikováno v:
Archives of Toxicology
Archives of toxicology, 91(2):839-864
Archives of toxicology, 91(2):839-864
Stem cell-based in vitro test systems can recapitulate specific phases of human development. In the UKK test system, human pluripotent stem cells (hPSCs) randomly differentiate into cells of the three germ layers and their derivatives. In the UKN1 te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff93042e666a7b6649c008993533a28c
Autor:
Davood Sabour, Agapios Sachinidis, Kurt Pfannkuche, Frank Suhr, Peter Dröge, Osama M. Abd El Aziz, John Antonydas Gaspar, Kesavan Meganathan, Wael Attia, Johannes Winkler, Markus Khalil, Konrad Brockmeier, Jürgen Hescheler, Smita Jagtap, Dimitry Spitkovsky
Publikováno v:
Stem Cell Reviews and Reports. 10:1-15
Pluripotent stem cells have great potential for regenerative medicine; however, their clinical use is associated with a risk of tumor formation. We utilized pluripotent cells expressing green fluorescent protein and puromycin resistance under control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c908b8a1ce1f11cfaee396739dad1ae1
https://doi.org/10.1007/s12015-013-9472-1
https://doi.org/10.1007/s12015-013-9472-1
Autor:
Giovanna Lazzari, Juergen Hescheler, Agapios Sachinidis, Smita Jagtap, John Antonydas Gaspar, Cesare Galli, Kesavan Meganathan, Silvia Colleoni
Publikováno v:
Current Medicinal Chemistry; Vol 19
Current Medicinal Chemistry
Current Medicinal Chemistry
The development of in vitro testing strategies for chemical and drug screening is a priority need in order to protect human health, to increase safety, to reduce the number of animals required for conventional testing methods and finally to meet the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31778ed9c6a0c654ea8aa908271aa975
https://doi.org/10.2174/092986712804485926
https://doi.org/10.2174/092986712804485926
Autor:
Kesavan Meganathan, S. Bremer-Hoffmann, John Antonydas Gaspar, Smita Jagtap, Agapios Sachinidis, Roberto Ensenat-Waser, Juergen Hescheler, Kinga Vojnits
Publikováno v:
Current Medicinal Chemistry. 19:6224-6232
Traditional approaches in evaluating the hazard of drug candidates on the developing offspring are often time-consuming and cost-intensive. Moreover, variations in the toxicological response of different animal species to the tested substance cause s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cd15e2f79577e766dbfabf39953b6a6
https://doi.org/10.2174/092986712804485728
https://doi.org/10.2174/092986712804485728
Publikováno v:
Pluripotent Stem Cells-From the Bench to the Clinic
Traditional approaches to toxicological testing are expensive and time consuming usually involving exposure of chemicals to large numbers of animals during the crucial period of organ development. In order to provide cost-efficient and high-throughpu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce3982873d3f3049c9b1ce8d87626f3
https://doi.org/10.5772/63929
https://doi.org/10.5772/63929
