Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Smita Eknath Desale"'
Publikováno v:
Molecular Biomedicine, Vol 2, Iss 1, Pp 1-18 (2021)
Abstract Alzheimer’s disease is a progressive neurodegenerative disease characterized by the presence of amyloid-β plaques in the extracellular environment and aggregates of Tau protein that forms neurofibrillary tangles (NFTs) in neuronal cells.
Externí odkaz:
https://doaj.org/article/9a447cae62094a61ae55574c14430768
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-12 (2021)
Abstract Alzheimer’s disease is one of the neurodegenerative diseases, characterized by the accumulation of abnormal protein deposits, which disrupts signal transduction in neurons and other glia cells. The pathological protein in neurodegenerative
Externí odkaz:
https://doaj.org/article/84a461fa94894b9e99c0cd3f69601270
Publikováno v:
Molecular Biomedicine, Vol 2, Iss 1, Pp 1-14 (2021)
Abstract Alzheimer’s disease (AD) is known by characteristic features, extracellular burden of amyloid-β and intracellular neuronal Tau. Microglia, the innate immune cell of the brain has the ability to clear the burden of accumulated proteins via
Externí odkaz:
https://doaj.org/article/200320c1adc644d7a8ec5eb18482183b
Publikováno v:
Cell Adhesion & Migration, Vol 15, Iss 1, Pp 84-100 (2021)
Microglia, the resident immune cells, were found to be activated to inflammatory phenotype in Alzheimer’s disease (AD). The extracellular burden of amyloid-β plaques and Tau seed fabricate the activation of microglia. The seeding effect of extrace
Externí odkaz:
https://doaj.org/article/a6211053c1a546149991008cc7753d11
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-14 (2020)
Abstract Microglial polarization is an utmost important phenomenon in Alzheimer’s disease that influences the brain environment. Polarization depends upon the types of responses that cells undergo, and it is characterized by receptors present on th
Externí odkaz:
https://doaj.org/article/8abf0f81f3a54d169d4f2a538b5f1ba5
Background The polarized migratory microglia consisting of front edge lamellipodia and rear edge uropod direct migration at the chemotactic gradient. Thus, maintenance of polarized morphology of the cell is utmost to sense the extracellular signal an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a46310edec97dbd9ab8f2378057b620b
https://doi.org/10.21203/rs.3.rs-2695599/v1
https://doi.org/10.21203/rs.3.rs-2695599/v1
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1870:119477
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d3d0dad76c25045d28f05f5cccf775f
https://doi.org/10.1016/j.bbamcr.2023.119477
https://doi.org/10.1016/j.bbamcr.2023.119477
Publikováno v:
International journal of biological macromolecules. 166
Alzheimer's disease is characterized by important patho-proteins, which being composed of Amyloid-β plaques and intracellular neurofibrillary tangles of Tau. Intrinsically disordered protein tau has several interacting partners, which are necessary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a512c6b480b4e749dc8d0f7185c835d3
https://pubmed.ncbi.nlm.nih.gov/33130263
https://pubmed.ncbi.nlm.nih.gov/33130263
Publikováno v:
Molecular Biomedicine, Vol 2, Iss 1, Pp 1-14 (2021)
Molecular Biomedicine
Molecular Biomedicine
Alzheimer’s disease (AD) is known by characteristic features, extracellular burden of amyloid-β and intracellular neuronal Tau. Microglia, the innate immune cell of the brain has the ability to clear the burden of accumulated proteins via phagocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9cacaf14ebc23dbf0423766e890c9f
https://pubmed.ncbi.nlm.nih.gov/35006402
https://pubmed.ncbi.nlm.nih.gov/35006402
Alzheimer’s disease is one of the neurodegenerative diseases, characterized by the accumulation of abnormal protein deposits, which disrupt the signal transduction in neurons and other glia cells. The pathological protein Tau and amyloid-β contrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112c5161a7e4faa7e4a0ecdccf913ef0
https://doi.org/10.20944/preprints202007.0532.v1
https://doi.org/10.20944/preprints202007.0532.v1