Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Smircich P"'
Autor:
Carlos Romeo-Cardeillac, María Fernanda Trovero, Santiago Radío, Pablo Smircich, Rosana Rodríguez-Casuriaga, Adriana Geisinger, José Sotelo-Silveira
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract Background Mammalian testis is a highly complex and heterogeneous tissue. This complexity, which mostly derives from spermatogenic cells, is reflected at the transcriptional level, with the largest number of tissue-specific genes and long no
Externí odkaz:
https://doaj.org/article/f7cc095aa7114a3c8eb733a381fd4e6f
Autor:
Karina B Sabalette, Vanina A Campo, José R Sotelo-Silveira, Pablo Smircich, Javier G De Gaudenzi
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 5, p e0012179 (2024)
BackgroundDuring its life cycle, the human pathogen Trypanosoma cruzi must quickly adapt to different environments, in which the variation in the gene expression of the regulatory U-rich RNA-binding protein 1 (TcUBP1) plays a crucial role. We have pr
Externí odkaz:
https://doaj.org/article/65667e548fd949e3996b4b818d6046d3
Autor:
Karina B. Sabalette, Vanina A. Campo, José R. Sotelo-Silveira, Pablo Smircich, Javier G. De Gaudenzi
Publikováno v:
Data in Brief, Vol 53, Iss , Pp 110156- (2024)
Previous studies have shown that overexpression of the Trypanosoma cruzi U-rich RNA-binding protein 1 (TcUBP1) in insect-dwelling epimastigotes results in a gene expression pattern resembling that of the infective form of the pathogen. Here, we used
Externí odkaz:
https://doaj.org/article/8b405d9128024c9a82da4e4a9040cae7
Autor:
Alvarez-Valín Fernando, Carmona Carlos, Roche Leda, Rinaldi Gabriel, Smircich Pablo, Dell'Oca Nicolás, da Silva Edileuza, Ruétalo Natalia, Cancela Martín, Zaha Arnaldo, Tort José F
Publikováno v:
BMC Genomics, Vol 11, Iss 1, p 227 (2010)
Abstract Background The common liver fluke Fasciola hepatica is the agent of a zoonosis with significant economic consequences in livestock production worldwide, and increasing relevance to human health in developing countries. Although flukicidal dr
Externí odkaz:
https://doaj.org/article/b8496f3ea63a4b048b0fc04c037fb9e4
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Trypanosoma cruzi is a digenetic unicellular parasite that alternates between a blood-sucking insect and a mammalian, host causing Chagas disease or American trypanosomiasis. In the insect gut, the parasite differentiates from the non-replicative try
Externí odkaz:
https://doaj.org/article/2fba4634957c4806a24d9737c7a9ded3
Autor:
Martin Rivara-Espasandín, Miranda Clara Palumbo, Ezequiel J. Sosa, Santiago Radío, Adrián G. Turjanski, José Sotelo-Silveira, Dario Fernandez Do Porto, Pablo Smircich
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction:Trypanosoma cruzi, Trypanosoma brucei, and Leishmania spp., commonly referred to as TriTryps, are a group of protozoan parasites that cause important human diseases affecting millions of people belonging to the most vulnerable population
Externí odkaz:
https://doaj.org/article/a72ac4a77d9b41bab1b19086c7739ec5
Autor:
Paula Beati, Milena Massimino Stepñicka, Salomé C Vilchez Larrea, Pablo Smircich, Guillermo D Alonso, Josefina Ocampo
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0293809 (2023)
In Trypanosoma cruzi DNA is packaged into chromatin by octamers of histone proteins that form nucleosomes. Transcription of protein coding genes in trypanosomes is constitutive producing polycistronic units and gene expression is primarily regulated
Externí odkaz:
https://doaj.org/article/1317c725e81d46f497a6e524b3b23e83
Autor:
Natalia Rego, Alicia Costábile, Mercedes Paz, Cecilia Salazar, Paula Perbolianachis, Lucía Spangenberg, Ignacio Ferrés, Rodrigo Arce, Alvaro Fajardo, Mailen Arleo, Tania Possi, Natalia Reyes, Ma Noel Bentancor, Andrés Lizasoain, María José Benítez, Viviana Bortagaray, Ana Moller, Gonzalo Bello, Ighor Arantes, Mariana Brandes, Pablo Smircich, Odhille Chappos, Melissa Duquía, Belén González, Luciana Griffero, Mauricio Méndez, Ma Pía Techera, Juan Zanetti, Bernardina Rivera, Matías Maidana, Martina Alonso, Cecilia Alonso, Julio Medina, Henry Albornoz, Rodney Colina, Veronica Noya, Gregorio Iraola, Tamara Fernández-Calero, Gonzalo Moratorio, Pilar Moreno
Publikováno v:
Emerging Infectious Diseases, Vol 27, Iss 11, Pp 2957-2960 (2021)
We developed a genomic surveillance program for real-time monitoring of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) in Uruguay. We report on a PCR method for SARS-CoV-2 VOCs, the surveillance workflow, and
Externí odkaz:
https://doaj.org/article/2f8c2c697f7c416e89888ac0d7ad55f7