Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Smink Luc J"'
Autor:
Burren Oliver S, Healy Barry C, Lam Alex C, Schuilenburg Helen, Dolman Geoffrey E, Everett Vincent H, Laneri Davide, Nutland Sarah, Rance Helen E, Payne Felicity, Smyth Deborah, Lowe Chris, Barratt Bryan J, Twells Rebecca CJ, Rainbow Daniel B, Wicker Linda S, Todd John A, Walker Neil M, Smink Luc J
Publikováno v:
Human Genomics, Vol 1, Iss 2, Pp 98-109 (2004)
Abstract The genetic dissection of complex disease remains a significant challenge. Sample-tracking and the recording, processing and storage of high-throughput laboratory data with public domain data, require integration of databases, genome informa
Externí odkaz:
https://doaj.org/article/823c52cce9af4db5ab229c0b9b6a76d1
Autor:
Todd John A, Smink Luc J, Cheng Tammy, Priego Eva-Maria, Worth Catherine L, Burke David F, Blundell Tom L
Publikováno v:
BMC Bioinformatics, Vol 8, Iss 1, p 301 (2007)
Abstract Background Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the most common of which is the non-synonymous single nucleotide polym
Externí odkaz:
https://doaj.org/article/288ea7b92c554761ba5a92368884da4e
Autor:
Barratt Bryan J, Twells Rebecca, Smith Anne, Walker Neil M, Nutland Sarah, Stevens Helen, Burren Oliver, Lam Alex, Godfrey Lisa, Masters Jennifer, Payne Felicity, Lowe Christopher E, Bailey Rebecca, Smyth Deborah, Smink Luc J, Nejentsev Sergey, Wright Charmain, French Lisa, Chen Yuan, Deloukas Panagiotis, Rogers Jane, Dunham Ian, Todd John A
Publikováno v:
BMC Genetics, Vol 8, Iss 1, p 24 (2007)
Abstract Background In an effort to locate susceptibility genes for type 1 diabetes (T1D) several genome-wide linkage scans have been undertaken. A chromosomal region designated IDDM10 retained genome-wide significance in a combined analysis of the m
Externí odkaz:
https://doaj.org/article/37dd7d5fadb64df7abd0af79d4612388
Autor:
Smink Luc J, Walker Neil M, Burren Oliver, Lam Alex C, Healy Barry C, Nutland Sarah, Bailey Rebecca, Smyth Deborah J, Cooper Jason D, Lowe Christopher E, Taniguchi Hidenori, Wicker Linda S, Todd John A
Publikováno v:
BMC Genetics, Vol 7, Iss 1, p 22 (2006)
Abstract Background Type 1 diabetes (T1D) is a common autoimmune disease resulting from T-cell mediated destruction of pancreatic beta cells. Decay accelerating factor (DAF, CD55), a glycosylphosphatidylinositol-anchored membrane protein, is a candid
Externí odkaz:
https://doaj.org/article/7011c124141642e49bf19ba66e134d25
Autor:
Savage David A, Ionescu-Tîrgovişte Constantin, Guja Cristian, Rønningen Kjersti S, Undlien Dag E, Nutland Sarah, Walker Neil, Chamberlain Giselle, Hunter Kara M, Moule Carolyn, Fraser Heather, Smink Luc J, Hulme John, Lowe Christopher, Pask Rebecca, Cooper Jason D, Payne Felicity, Vella Adrian, Smyth Deborah J, Maier Lisa M, Strachan David P, Peterson Laurence B, Todd John A, Wicker Linda S, Twells Rebecca C
Publikováno v:
BMC Genetics, Vol 6, Iss 1, p 9 (2005)
Abstract Background One strategy to help identify susceptibility genes for complex, multifactorial diseases is to map disease loci in a representative animal model of the disorder. The nonobese diabetic (NOD) mouse is a model for human type 1 diabete
Externí odkaz:
https://doaj.org/article/2b7072e4c270452e9ad91752c0430b47
Autor:
Smink Luc J, Lam Alex C, Smith Anne, Twells Rebecca CJ, Sebastian Meera, Smyth Deborah J, Nutland Sarah, Barratt Bryan J, Rance Helen E, Pask Rebecca, Walker Neil M, Todd John A
Publikováno v:
BMC Biotechnology, Vol 4, Iss 1, p 15 (2004)
Abstract Background Sustainable DNA resources and reliable high-throughput genotyping methods are required for large-scale, long-term genetic association studies. In the genetic dissection of common disease it is now recognised that thousands of samp
Externí odkaz:
https://doaj.org/article/aef12a9d76b845ad98c433c5e1222732
Autor:
Kim, Ung-Jin, Shizuya, Hiroaki, Kang, Hyung-Lyun, Choi, Sun-Shim, Garrett, Charmain L., Smink, Luc J., Birren, Bruce W., Korenberg, Julie R., Dunham, Ian, Simon, Melvin I.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1996 Jun . 93(13), 6297-6301.
Externí odkaz:
https://www.jstor.org/stable/39299
Autor:
Maier, Lisa M, Smyth, Deborah J, Vella, Adrian, Payne, Felicity, Cooper, Jason D, Pask, Rebecca, Lowe, Christopher, Hulme, John, Smink, Luc J, Fraser, Heather, Moule, Carolyn, Hunter, Kara M, Chamberlain, Giselle, Walker, Neil, Nutland, Sarah, Undlien, Dag E, Rønningen, Kjersti S, Guja, Cristian, Ionescu-Tîrgovişte, Constantin, Savage, David A, Strachan, David P, Peterson, Laurence B, Todd, John A, Wicker, Linda S, Twells, Rebecca C
Publikováno v:
BMC Genetics. 2005 Feb 18;6(1):9
Externí odkaz:
http://hdl.handle.net/10852/46773
https://www.duo.uio.no/bitstream/handle/10852/46773/1/12863_2004_Article_215.pdf
https://www.duo.uio.no/bitstream/handle/10852/46773/1/12863_2004_Article_215.pdf
