Serum levels of biomarkers related to severity staging of Raynaud's phenomenon, neurosensory manifestations, and vibration exposure in patients with hand-arm vibration injury.

Autor: Tekavec, Eva¹ (AUTHOR) eva.tekavec@med.lu.se, Nilsson, Tohr² (AUTHOR), Dahlin, Lars B.³ (AUTHOR), Huynh, Elizabeth⁴ (AUTHOR), Nordander, Catarina¹ (AUTHOR), Riddar, Jakob¹ (AUTHOR), Kåredal, Monica^1,4 (AUTHOR)

Publikováno v: Scientific Reports. 8/5/2024, Vol. 14 Issue 1, p1-9. 9p.

Observational Retrospective Study in Patients Treated with Galcanezumab as Preventive Treatment for Migraine: The ORYGAM Study.

Autor: Díaz Insa, Samuel¹ (AUTHOR), Guerrero, Ángel² (AUTHOR), Viguera, Javier³ (AUTHOR), Medrano Martínez, Vicente⁴ (AUTHOR), Calle de Miguel, Carlos⁵ (AUTHOR), Porta-Etessam, Jesús⁶ (AUTHOR), Ciudad, Antonio⁷ (AUTHOR), Diaz-Cerezo, Silvia⁷ (AUTHOR), Roncero Martín, Ana⁸ (AUTHOR), Núñez, Mercedes⁷ (AUTHOR) nunez_mercedes@lilly.com

Publikováno v: Pain & Therapy. Jun2024, Vol. 13 Issue 3, p557-576. 20p.

Transferable deep generative modeling of intrinsically disordered protein conformations.

Autor: Janson, Giacomo¹ (AUTHOR), Feig, Michael¹ (AUTHOR) mfeiglab@gmail.com

Publikováno v: PLoS Computational Biology. 5/23/2024, Vol. 20 Issue 5, p1-28. 28p.

A Novel α-Calcitonin Gene-Related Peptide Analogue Protects Against End-Organ Damage in Experimental Hypertension, Cardiac Hypertrophy, and Heart Failure.

Autor: Aubdool AA; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.)., Thakore P; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.)., Argunhan F; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.)., Smillie SJ; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.)., Schnelle M; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.)., Srivastava S; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.)., Alawi KM; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.)., Wilde E; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.)., Mitchell J; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.)., Farrell-Dillon K; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.)., Richards DA; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.)., Maltese G; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.)., Siow RC; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.)., Nandi M; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.)., Clark JE; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.)., Shah AM; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.)., Sams A; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.)., Brain SD; From Cardiovascular Division, BHF Centre of Research Excellence and Centre of Integrative Biomedicine, King's College London, United Kingdom (A.A.A., F.A., S.-J.S., S.S., K.M.A., E.W., J.M., K.F.-D., G.M., R.C.S., S.D.B.); Institute of Pharmaceutical Sciences, King's College London, United Kingdom (P.T., M.N.); Cardiovascular Division, BHF Centre of Research Excellence, James Black Centre, King's College London, United Kingdom (M.S., D.A.R., A.M.S.); Department of Cardiology and Pneumology, Medical Center Goettingen, Germany (M.S.); Cardiovascular Division, BHF Centre of Research Excellence, Rayne Institute, St Thomas' Hospital, King's College London, United Kingdom (J.E.C.); Novo Nordisk A/S, Diabetic Complications Biology, Novo Nordisk Park, Maaloev, Denmark (A.S.); and Department of Clinical Experimental Research, Glostrup Research Institute, Rigshospitalet, Denmark (A.S.). sue.brain@kcl.ac.uk.

Publikováno v: Circulation [Circulation] 2017 Jul 25; Vol. 136 (4), pp. 367-383. Date of Electronic Publication: 2017 Apr 26.

Transcript-dependent effects of the CALCA gene on the progression of post-traumatic osteoarthritis in mice.

Autor: Jiang, Shan¹ (AUTHOR), Xie, Weixin¹ (AUTHOR), Knapstein, Paul Richard¹ (AUTHOR), Donat, Antonia¹ (AUTHOR), Albertsen, Lilly-Charlotte¹ (AUTHOR), Sevecke, Jan¹ (AUTHOR), Erdmann, Cordula¹ (AUTHOR), Appelt, Jessika² (AUTHOR), Fuchs, Melanie² (AUTHOR), Hildebrandt, Alexander^2,3 (AUTHOR), Maleitzke, Tazio^2,3,4,5,6 (AUTHOR), Frosch, Karl-Heinz^1,7 (AUTHOR), Baranowsky, Anke¹ (AUTHOR), Keller, Johannes¹ (AUTHOR) j.keller@uke.de

Publikováno v: Communications Biology. 2/23/2024, Vol. 7 Issue 1, p1-12. 12p.