Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Smijin K Soman"'
Publikováno v:
Frontiers in Aging, Vol 4 (2023)
Externí odkaz:
https://doaj.org/article/75082708ff414287a5cdeb3a64437ddb
Autor:
Smijin K. Soman, Ruben K. Dagda
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Mitochondrial dysfunction plays a significant role in the pathogenesis of Parkinson’s disease (PD). Consistent with this concept, loss of function mutations in the serine/threonine kinase- PINK1 (PTEN-induced putative kinase-1) causes autosomal rec
Externí odkaz:
https://doaj.org/article/41c79a9ff9c54c86a5845be84656d223
Publikováno v:
Biology Open, Vol 8, Iss 10 (2019)
The loss of dopaminergic neurons (DA) is a pathological hallmark of sporadic and familial forms of Parkinson's disease (PD). We have previously shown that inhibiting mitochondrial calcium uniporter (mcu) using morpholinos can rescue DA neurons in the
Externí odkaz:
https://doaj.org/article/d41f2a9893ab40b1907f2c3cd99909ca
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2497
The measurement of mitochondrial function has become imperative to understand and characterize diseases characterized by bioenergetic alterations. The advancement of automation and application of high-throughput technologies has propelled our underst
Publikováno v:
J Neurosci Res
Mutations in PTEN-induced kinase 1 (PINK1) lead to early onset autosomal recessive Parkinson's disease in humans. In healthy neurons, full-length PINK1 (fPINK1) is post-translationally cleaved into different lower molecular weight forms, and cleaved
Publikováno v:
Methods in Molecular Biology ISBN: 9781071623084
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::699dda94341a6c0d565ee1955d630097
https://doi.org/10.1007/978-1-0716-2309-1_26
https://doi.org/10.1007/978-1-0716-2309-1_26
Autor:
Ruben K. Dagda, Smijin K. Soman
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience
Frontiers in Neuroscience
Mitochondrial dysfunction plays a significant role in the pathogenesis of Parkinson’s disease (PD). Consistent with this concept, loss of function mutations in the serine/threonine kinase- PINK1 (PTEN-induced putative kinase-1) causes autosomal rec