Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Smidt Pauline S"'
Autor:
Amimeur Tileli, Clark Rutilio H, Josh Smith, Danielle Van Citters, Bruce A. Kerwin, Jeremy M. Shaver, Randal R. Ketchem, Christine C. Siska, Smidt Pauline S, Megan Sprague, Dean Pettit, J. Alex Taylor
We demonstrate the use of a Generative Adversarial Network (GAN), trained from a set of over 400,000 light and heavy chain human antibody sequences, to learn the rules of human antibody formation. The resulting model surpasses common in silico techni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c13fde634263f9f22e3613107036384e
Publikováno v:
Biotechnology progressREFERENCES. 35(5)
In order to avoid the metabolic burden of protein expression during cell growth, and to avoid potential toxicity of recombinant proteins, microbial expression systems typically utilize regulated expression vectors. In contrast, constitutive expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f430a4f1c822d867995ebe44390a6e47
https://pubmed.ncbi.nlm.nih.gov/31090257
https://pubmed.ncbi.nlm.nih.gov/31090257
Autor:
Dean Pettit, Kevin J. Whaley, Jane Ennis, Michael T. Trentalange, Richard S. Rogers, Danielle Pace, Alison J. Gillespie, Brittney Livingston, Edith Nalbandian, Chris Crowell, Kelly K. Arthur, Ron Gillespie, Michael H. Pauly, Yan Brodsky, Ken Timmons, James N Thomas, Larry Zeitlin, Smidt Pauline S, Clark Rutilio H
Publikováno v:
mAbs. 8:347-357
From March 2014 through February 2015, the Ebola virus spread rapidly in West Africa, resulting in almost 30,000 infections and approximately 10,000 deaths. With no approved therapeutic options available, an experimental antibody cocktail known as ZM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a826eabda805f303ddee6591711508
https://doi.org/10.1080/19420862.2015.1127492
https://doi.org/10.1080/19420862.2015.1127492
Publikováno v:
New Developments and New Applications in Animal Cell Technology ISBN: 0792350162
We have tested the effect of a wide variety of lipid supplements and precursors on the growth of a recombinant Chinese Hamster Ovary (CHO) cell line. This cell line is adapted to grow in protein-free media and grows slowly in the absence of any exoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a74b0dcff004922443817d899a99fdd
https://doi.org/10.1007/0-306-46860-3_36
https://doi.org/10.1007/0-306-46860-3_36
Autor:
Smidt Pauline S, Chi-Chang Lee, Carol Krantz, Teri L. Aldrich, Karmen Hodges, James N. Thomas, Arvia E. Morris
Publikováno v:
Animal Cell Technology ISBN: 9789401062732
We have isolated a 5.7kb Chinese hamster ovary (CHO) genomic sequence that can improve expression of reporter proteins in stable cell pools when inserted upstream of the CMV promoter/enhancer. This expression augmenting sequence element (EASE) was id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::861d9ca868b8c55cf4f0a5428271e601
https://doi.org/10.1007/978-94-011-5404-8_84
https://doi.org/10.1007/978-94-011-5404-8_84